Common features of aging fail to occur in Drosophila raised without a bacterial microbiome

Brain aging comprises many modes of structural and functional change with distinct genetic and biophysical associations

(2020) Stephen M Smith et al.   eLife

Circadian regulation of mitochondrial uncoupling and lifespan

(2020) Matt Ulgherait et al.   Nature Communications

DAF-16 and SMK-1 Contribute to Innate Immunity During Adulthood in Caenorhabditis elegans

(2020) Daniel R. McHugh et al.   G3-Genes Genomes Genetics

Meta-analysis of Diets Used in Drosophila Microbiome Research and Introduction of the Drosophila Dietary Composition Calculator (DDCC)

(2020) Danielle N. A. Lesperance et al.   G3-Genes Genomes Genetics

A single-cell transcriptomic atlas characterizes ageing tissues in the mouse

(2020)   NATURE

Hyperactive Innate Immunity Causes Degeneration of Dopamine Neurons upon Altering Activity of Cdk5

(2019) Arvind Kumar Shukla et al.   Cell Reports

The proteostasis network and its decline in ageing

(2019) Mark S. Hipp et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The role of commensal microbes in the lifespan of Drosophila melanogaster

(2019) Hye-Yeon Lee et al.   Aging-US

Publisher Correction: Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly

(2019) Peer Aramillo Irizar et al.   Nature Communications

Cross-species functional modules link proteostasis to human normal aging

(2019) Andrea Komljenovic et al.   PLoS Computational Biology

Host-Microbe-Drug-Nutrient Screen Identifies Bacterial Effectors of Metformin Therapy

(2019) Rosina Pryor et al.   CELL

Altered expression of the Cdk5 activator-like protein, Cdk5α, causes neurodegeneration, in part by accelerating the rate of aging

(2018) Joshua Spurrier et al.   Disease Models & Mechanisms

The generational scalability of single-cell replicative aging

(2018) Ping Liu et al.   Science Advances

Symbiont-Driven Male Mating Success in the Neotropical Drosophila paulistorum Superspecies

(2018) Daniela I. Schneider et al.   BEHAVIOR GENETICS

Brain transcriptome changes in the aging Drosophila melanogaster accompany olfactory memory performance deficits

(2018) Rodrigo Pacifico et al.   PLoS One

Microbiome interactions shape host fitness

(2018) Alison L. Gould et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut microbiomes and reproductive isolation inDrosophila

(2017) Philip T. Leftwich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Commensal bacteria and essential amino acids control food choice behavior and reproduction

(2017) Ricardo Leitão-Gonçalves et al.   PLOS BIOLOGY

Regulation of life span by the gut microbiota in the short-lived African turquoise killifish

(2017) Patrick Smith et al.   eLife

Aging causes decreased resistance to multiple stresses and a failure to activate specific stress response pathways

(2016) Dylan J. Dues et al.   Aging-US

The temporal scaling of Caenorhabditis elegans ageing

(2016) Nicholas Stroustrup et al.   NATURE

Regulation of prefrontal cortex myelination by the microbiota

(2016) A E Hoban et al.   Translational Psychiatry

Glucose modulatesDrosophilalongevity and immunity independent of the microbiota

(2016) Anthony Galenza et al.   Biology Open

Gene expression defines natural changes in mammalian lifespan

(2015) Alexey A. Fushan et al.   AGING CELL

Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality

(2015) Rebecca I. Clark et al.   Cell Reports

Microbes Promote Amino Acid Harvest to Rescue Undernutrition in Drosophila

(2015) Ryuichi Yamada et al.   Cell Reports

Why Is Aging Conserved and What Can We Do about It?

(2015) Jason N. Pitt et al.   PLOS BIOLOGY

Animal Models of Aging Research: Implications for Human Aging and Age-Related Diseases

(2015) Sarah J. Mitchell et al.   Annual Review of Animal Biosciences

PGRP-SC2 Promotes Gut Immune Homeostasis to Limit Commensal Dysbiosis and Extend Lifespan

(2014) Linlin Guo et al.   CELL

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

A Deregulated Intestinal Cell Cycle Program Disrupts Tissue Homeostasis without Affecting Longevity in Drosophila

(2014) Kristina Petkau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Macromolecular Damage in Aging and Age-related Disease

(2014) A. G. Richardson et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Microbiota-Induced Changes in Drosophila melanogaster Host Gene Expression and Gut Morphology

(2014) N. A. Broderick et al.   mBio

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Aging modulates cuticular hydrocarbons and sexual attractiveness in Drosophila melanogaster

(2012) T.-H. Kuo et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Lactobacillus plantarum Promotes Drosophila Systemic Growth by Modulating Hormonal Signals through TOR-Dependent Nutrient Sensing

(2011) Gilles Storelli et al.   Cell Metabolism

On the Programmed/Non-Programmed Nature of Ageing within the Life History

(2011) Thomas B.L. Kirkwood et al.   CURRENT BIOLOGY

Evaluation of potential reference genes for reverse transcription-qPCR studies of physiological responses in Drosophila melanogaster

(2011) Fleur Ponton et al.   JOURNAL OF INSECT PHYSIOLOGY

Meta-analysis of age-related gene expression profiles identifies common signatures of aging

(2009) João Pedro de Magalhães et al.   BIOINFORMATICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Long-Range Activation of Systemic Immunity through Peptidoglycan Diffusion in Drosophila

(2009) Mathilde Gendrin et al.   PLoS Pathogens

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH