The gut microbiome buffers dietary adaptation in Bronze Age domesticated dogs

In an attempt to explore the role of the gut microbiome during recent canine evolutionary history, we sequenced the metagenome of 13 canine coprolites dated ca. 3,600-3,450 years ago from the Bronze Age archaeological site of Solarolo (Italy), which housed a complex farming community. The microbiome structure of Solarolo dogs revealed continuity with that of modern dogs, but it also shared some features with the wild wolf microbiome, as a kind of transitional state between them. The dietary niche, as also inferred from the microbiome composition, was omnivorous, with evidence of consumption of starchy agricultural foods. Of interest, the Solarolo dog microbiome was particularly enriched in sequences encoding alpha-amylases and complemented a low copy number of the host amylase gene. These findings suggest that Neolithic dogs could have responded to the transition to a starch-rich diet by expanding microbial functionalities devoted to starch catabolism, thus compensating for delayed host response.

Automated summary

A study on the gut microbiome of canine coprolites from the Bronze Age site of Solarolo in Italy revealed continuity with modern dogs, as well as some similarities with wild wolves, indicating a transitional state. The dietary niche of the Solarolo dogs was omnivorous, with evidence of starch consumption, and their microbiome showed enrichment in sequences related to starch catabolism, suggesting adaptation to a starch-rich diet.