Article
Nanoscience & Nanotechnology
Yeyang Bu, Ruqi Huang, Zheng Li, Peng Zhang, Lijie Zhang, Yun Yang, Zhao Liu, Kaijin Guo, Fenglei Gao
Summary: The use of anisotropic truncated octahedral Au (TOh Au) coated with noble metal Pt enhances the surface plasmonic resonance and photocatalytic effect, providing strong support for cancer treatment.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Materials Science, Multidisciplinary
Anran Zhang, Yangping Zhang, Zhangmeng Liu, Gangan Huang, Lihua Wu, Yunzhi Fu, Xiaomei Wang, Yukou Du
Summary: This article reviews the development of anisotropic gold nanostructures, the properties of gold, and its potential for solar energy applications. It provides a detailed introduction to the stability, optical properties, and hot carrier states of gold. The characteristics of anisotropic gold nanostructures in different morphologies are summarized, and the maximum efficiency of solar light utilization is analyzed.
APPLIED MATERIALS TODAY
(2022)
Article
Green & Sustainable Science & Technology
W. Yang, B. Xia, L. Wang, S. Ma, H. Liang, D. Wang, J. Huang
Summary: Gold nanoparticles based Plasmonic Photothermal Therapy (PPTT) shows potential in cancer treatment by inducing local hyperthermia in cancer cells or tissues. Among three commonly studied gold nanostructures, gold nanostars (AuNSTs) demonstrate the highest photo-thermal conversion efficiency, making them the most promising agent for PTT therapy.
MATERIALS TODAY SUSTAINABILITY
(2021)
Review
Chemistry, Multidisciplinary
Earl Adrian D. R. Hans, Michelle D. Regulacio
Summary: Coupling Au and Cu2-xS on the nanoscale results in dual plasmonic Au-Cu2-xS nanocomposites with intense photon absorption and superior photothermal transduction efficiency, making them attractive for photothermal-based applications. Potential nanostructure configurations include heterodimer, core-shell, reverse core-shell, and yolk-shell arrangements, with different synthetic approaches presented in this Minireview. The photothermal behavior of these materials hints at their use as photothermally active agents in therapeutic applications.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Physical
Beata Tim, Paulina Blaszkiewicz, Michal Kotkowiak
Summary: This study explains how local excitation of gold nanorods (Au-NRs) causes a temperature increase in their vicinity and affects the properties of a model cell membrane. The results show that illumination of the Au-NRs changes the organization of the model membrane and makes it more stable and elastic. These findings are important for understanding how the photoactivation of nanoparticles influences the transport of medicinal substances.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Review
Chemistry, Analytical
Xiaowen Ou, Yuqi Liu, Mingxing Zhang, Li Hua, Shenshan Zhan
Summary: Plasmonic gold nanostructures, with unique optical properties and good biocompatibility, are ideal for developing methods in biosensing and bioimaging. This review summarizes the applications and techniques of biosensing and bioimaging in vitro and in vivo using plasmonic gold nanostructures.
Review
Biotechnology & Applied Microbiology
Mitchell Lee Taylor, Raymond Edward Wilson, Kristopher Daniel Amrhein, Xiaohua Huang
Summary: Noble metal nanoparticles, especially gold nanorods, have been widely used in cancer photothermal therapy due to their unique optical properties and long blood circulation half-life. This review summarizes the optical properties of gold nanorods and their applications in photothermal therapy, as well as recent strategies to improve the therapy through combination with chemotherapy and photodynamic therapy.
BIOENGINEERING-BASEL
(2022)
Article
Nanoscience & Nanotechnology
Varvara Athanasiou, Dimitra Stavroulaki, Foteini Arfara, Dimitrios Kampras, Ioannis Kleideris, Niki Roumelioti, Panagiota G. Fragouli, Georgios Patias, David Haddleton, Hermis Iatrou
Summary: A facile strategy for synthesizing hybrid nanoparticles with gold nanoshells that absorb NIR light was presented, allowing for fine-tuning of their optical properties. The nanoparticles showed significant temperature increase when irradiated with a low power laser, indicating their potential application in photothermal therapy.
ACS APPLIED NANO MATERIALS
(2021)
Article
Oncology
Asrin Pakravan, Roya Salehi, Mehrdad Mahkam
Summary: By synthesizing seven different shapes of gold nanoparticles, the study investigated the effect of shape on cellular uptake and photothermal therapy efficacy. The results showed that gold nanostars exhibited the lowest cytotoxicity, highest cellular uptake, and highest heat generation, indicating good potential for photothermal therapy.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2021)
Article
Chemistry, Physical
Yun Zhou, Peng Zheng, Fang Wang, Fangna Gu, Wenqing Xu, Qinyang Lu, Tingyu Zhu, Ziyi Zhong, Guangwen Xu, Fabing Su
Summary: This study successfully prepared a three-dimensional honeycomb N-doped carbon nanomaterial with good photothermal catalytic performance, and investigated the synergistic effect of NiO@Ni and NC on the CO2 reduction reaction and water splitting reaction.
Editorial Material
Biotechnology & Applied Microbiology
Ruixue Xiao, Jian Zeng, Fangyuan Li, Daishun Ling
Summary: Phototherapeutics is an increasingly popular cancer treatment, and gold-semiconductor nanocomposites have emerged as promising agents due to their tunability, biocompatibility, and diversity. This perspective explores the latest research on these nanohybrids for photodynamic, photothermal, and photocatalytic therapies, providing insights for the design and fabrication of novel composite nanoplatforms to enhance phototherapeutic efficiency and advance nanotechnology-based biomedical applications.
Review
Engineering, Biomedical
Zhuoqian Lv, Sijia He, Youfu Wang, Xinyuan Zhu
Summary: Developing anticancer therapeutic agents or technologies with high specificity, patient compliance, and low toxicity is important. Noble metal nanomaterials present strong potential for cancer treatment through photothermal therapy, with the ability to achieve multifunctional cancer therapy when combined with various functional reagents.
ADVANCED HEALTHCARE MATERIALS
(2021)
Article
Chemistry, Medicinal
Mansi Damani, Neha Desai, Bheeshma Pratap Singh, Raghumani Singh Ningthoujam, Munira Momin, Tabassum Khan
Summary: Hollow gold nanoparticles (HAuNPs) have attracted significant interest due to their excellent physicochemical and optical properties, with potential applications in diagnostics, sensing, imaging, and cancer treatment. This study successfully synthesized HAuNPs with surface plasmon resonance in the near infrared region through slight modifications to the synthesis method. Functionalization of these particles with suitable ligands further enhances their permeability and retention in cancer cells, making them potential candidates for cancer therapy.
JOURNAL OF PHARMACEUTICAL SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Xiao-Dan Liu, Bei Chen, Gang-Gang Wang, Song Ma, Li Cheng, Wei Liu, Li Zhou, Qu-Quan Wang
Summary: This study reports a method to synthesize asymmetric Bi2Se3/CdSe-Au hierarchical nanorods with excellent photothermal conversion efficiency, overcoming interfacial lattice mismatch and forming a Bi2Se3/CdSe heterojunction located at plasmonic hotspots of Au nanorods, demonstrating enhanced light absorption and charge separation.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Nanoscience & Nanotechnology
Oleksii O. Peltek, Timofey E. Karpov, Anna Rogova, Alisa Postovalova, Eduard Ageev, Andrey Petrov, Dmitri Antuganov, Andrei A. Stanzhevsky, Dmitri N. Maistrenko, Dmitry Zuev, Albert R. Muslimov, Alexander S. Timin, Mikhail Zyuzin
Summary: Conventional cancer therapy has limitations due to nonspecific action of anticancer drugs, but combining radio and photothermal therapy with nanocarriers can achieve complete tumor inhibition. The nanocarriers can be effectively labeled with 188Re therapeutic radionuclide and converted into heat with laser irradiation. Combined with paclitaxel, the treatment efficiency is significantly improved compared to monotherapy, showing potential for clinical translation.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Nanoscience & Nanotechnology
Reza Agabeigi, Seyed Hossein Rasta, Mohammad Rahmati-Yamchi, Roya Salehi, Effat Alizadeh
NANOSCALE RESEARCH LETTERS
(2020)
Article
Biophysics
Amin Sabzi, Akram Rahmani, Mahdi Edalati, Houman Kahroba, Mohammad Reza Dadpour, Roya Salehi, Amir Zarebkohan
COLLOIDS AND SURFACES B-BIOINTERFACES
(2020)
Article
Chemistry, Multidisciplinary
Mehdi Azizi, Hadi Valizadeh, Mehdi Shahgolzari, Mehdi Talebi, Elahe Baybordi, Mohammad Reza Dadpour, Roya Salehi, Mohammad Mehrmohammadi
Article
Biochemistry & Molecular Biology
Mahdieh Alipour, Sadaf Fadakar, Marziyeh Aghazadeh, Roya Salehi, Hossein Samadi Kafil, Leila Roshangar, Ensieh Mousavi, Zahra Aghazadeh
Summary: The study aimed to synthesize and evaluate a curcumin-based reparative endodontic material with antimicrobial and anti-inflammatory properties, as well as the ability to induce mineralization in human dental pulp stem cells. The CUR-based scaffolds showed antibacterial effects, inhibited inflammatory markers, and promoted mineralization in hDPSCs, suggesting their potential for healing and repairing the injured dentin-pulp complex.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
(2021)
Article
Oncology
Saeed Jafarirad, Sepide Mirzayinahr, Malihe Pooresmaeil, Roya Salehi
Summary: Photothermal therapy (PTT) is considered a promising new cancer treatment technique. In this study, a drug-free approach using a novel biocompatible nanocomposite as a PTT transducer was developed to kill MCF7 breast cancer cells. Characterization techniques confirmed the synthesis of the nanocomposite, and in vitro experiments showed significant cell death and apoptosis in breast cancer cells treated with the nanocomposite and subjected to laser irradiation.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2021)
Article
Cell Biology
Leila Mohammadzadeh, Mehrdad Mahkam, Abolfazl Barzegari, Abbas Karimi, Hossein Samadi Kafil, Roya Salehi, Reza Rahbarghazi
Summary: Polymeric nanofibrous scaffolds were fabricated and evaluated for their potential in cutaneous regeneration, with chitosan-containing scaffolds showing inhibition against Staphylococcus aureus. The presence of silver nanoparticles in the nanofibers was confirmed, and the prepared mats were deemed suitable for in vivo applications. Antifungal activity was not observed against Candida albicans.
Article
Biotechnology & Applied Microbiology
Baharak Divband, Bahareh Pouya, Mehdi Hassanpour, Mahdieh Alipour, Roya Salehi, Reza Rahbarghazi, Sahriar Shahi, Zahra Aghazadeh, Marziyeh Aghazadeh
Summary: This study developed bFGF-loaded PCL/CS scaffolds and investigated their effects on angiogenesis in hDPSCs. The results showed that the PCL/CS/bFGF group significantly increased cell adhesion and survival rate, as well as the expression levels of VEGFR-2, Tie2, and Angiopoietin-1 genes.
BIOMED RESEARCH INTERNATIONAL
(2022)
Article
Polymer Science
Nasrin Valizadeh, Roya Salehi, Leila Roshangar, Samira Agbolaghi, Mehrdad Mahkam
Summary: The study found that loading SA extract into PCL/GEL nanofibrous scaffolds can improve mechanical properties and physical qualities, promote cell attachment and mineralization, and enhance the expression of osteogenic genes. The results indicate that PCL/GEL/SA nanofibers have great potential for bone tissue engineering.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Engineering, Biomedical
Nasrin Valizadeh, Roya Salehi, Marziyeh Aghazadeh, Mahdieh Alipour, Hadi Sadeghzadeh, Mehrdad Mahkam
Summary: This study investigated the effects of bitter almond extract on the osteoblast differentiation of human dental pulp stem cells. The results showed that the addition of bitter almond extract improved the mechanical properties of the scaffolds and promoted cell attachment, proliferation, and osteogenic differentiation. Therefore, bitter almond extract has great potential for bone tissue engineering applications.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Article
Pharmacology & Pharmacy
Yasamin Davatgaran Taghipour, Roya Salehi, Amir Zarebkohan, Ziba Zakeri, Monireh Khordadmehr, Yousef Saeedi Honar, Vladimir P. Torchilin
Summary: The study developed dual targeted nanoparticles modified with CSRLSLPGSSSKpalmSSS peptide and TA1 aptamer, which showed reduced protein corona formation and enhanced accumulation in the tumor microenvironment. In vitro and in vivo experiments demonstrated their superior therapeutic effect on breast cancer models, with a lower therapeutic dosage of SAL.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Chemistry, Multidisciplinary
Ziba Zakeri, Roya Salehi, Mehrdad Mahkam, Vahid Siahpoush, Reza Rahbarghazi, Emel Sokullu, Farhang Abbasi
Summary: It is acknowledged that interfacial reactions between biomaterial surfaces and host tissues play a significant role in engineered tissues. The lack of functional groups limits long-term biocompatibility and successful biological response of biomaterials. This study successfully modified the surface of POSS-PCUU nanofibers by grafting PAAc using two-step argon-air DBD plasma, enhancing cell-biomaterial affinity and providing desired tissue properties.
JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS
(2023)
Article
Medicine, Research & Experimental
Fahima Danesh Pouya, Roya Salehi, Yousef Rasmi, Fatemeh Kheradmand, Anahita Fathi-Azarbayjani
Summary: In this study, CAP and PGZ were co-encapsulated in TB nanoparticles and evaluated for their cytotoxic and apoptotic effects on colorectal cancer cells and human umbilical vein endothelial cells (HUVECs). The nanoparticles showed synergistic effects in inducing apoptosis in all tested cells, suggesting their potential as a targeted combinational therapy for colorectal cancer.
Article
Pharmacology & Pharmacy
Mehrdad Mahkam, Fatemeh Bazmi Zeynabad, Effat Alizadeh, Mahdi Rahimi, Fariborz Rahimi, Roya Salehi
Summary: The newly developed smart nanocomposites are potentially effective pH-sustainable delivery systems for enhanced tumor therapy.
ADVANCED PHARMACEUTICAL BULLETIN
(2021)
Article
Chemistry, Multidisciplinary
Akram Rahmani, Hassan Zavvar Mousavi, Roya Salehi, Ahmad Bagheri
