Polygenic Risk Score–Enhanced Risk Stratification of Coronary Artery Disease in Patients With Stable Chest Pain

Predictive Accuracy of a Polygenic Risk Score–Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease

(2020) Joshua Elliott et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Predictive Accuracy of a Polygenic Risk Score Compared With a Clinical Risk Score for Incident Coronary Heart Disease

(2020) Jonathan D. Mosley et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Genetic Risk of Coronary Artery Disease, Features of Atherosclerosis, and Coronary Plaque Burden

(2020) Morten Krogh Christiansen et al.   Journal of the American Heart Association

Non-parametric Polygenic Risk Prediction via Partitioned GWAS Summary Statistics

(2020) Sung Chun et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Limitations of Contemporary Guidelines for Managing Patients at High Genetic Risk of Coronary Artery Disease

(2020) Krishna G. Aragam et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Sexual Differences in Genetic Predisposition of Coronary Artery Disease

(2020) Yunfeng Huang et al.   Circulation-Genomic and Precision Medicine

Clinical use of current polygenic risk scores may exacerbate health disparities

(2019) Alicia R. Martin et al.   NATURE GENETICS

Polygenic prediction via Bayesian regression and continuous shrinkage priors

(2019) Tian Ge et al.   Nature Communications

Pre-test probability prediction in patients with a low to intermediate probability of coronary artery disease: a prospective study with a fractional flow reserve endpoint

(2019) Simon Winther et al.   European Heart Journal-Cardiovascular Imaging

Predicting Benefit From Evolocumab Therapy in Patients With Atherosclerotic Disease Using a Genetic Risk Score: Results From the FOURIER Trial

(2019) Nicholas A. Marston et al.   CIRCULATION

Patients with High Genome-Wide Polygenic Risk Scores for Coronary Artery Disease May Receive Greater Clinical Benefit from Alirocumab Treatment in the Odyssey Outcomes Trial

(2019) Amy Damask et al.   CIRCULATION

Making the Most of Clumping and Thresholding for Polygenic Scores

(2019) Florian Privé et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The personal and clinical utility of polygenic risk scores

(2018) Ali Torkamani et al.   NATURE REVIEWS GENETICS

Diagnosing coronary artery disease after a positive coronary computed tomography angiography: the Dan-NICAD open label, parallel, head to head, randomized controlled diagnostic accuracy trial of cardiovascular magnetic resonance and myocardial perfusion scintigraphy

(2018) L Nissen et al.   European Heart Journal-Cardiovascular Imaging

2018 ESC/EACTS Guidelines on myocardial revascularization

(2018) Franz-Josef Neumann et al.   EUROPEAN HEART JOURNAL

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

(2018) Amit V. Khera et al.   NATURE GENETICS

Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults

(2018) Michael Inouye et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA

(2018) Julius Gudmundsson et al.   Nature Communications

Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease

(2016) Amit V. Khera et al.   NEW ENGLAND JOURNAL OF MEDICINE

Danish study of Non-Invasive testing in Coronary Artery Disease (Dan-NICAD): study protocol for a randomised controlled trial

(2016) Louise Nissen et al.   Trials

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

(2015) Bjarni J. Vilhjálmsson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials

(2015) Jessica L Mega et al.   LANCET

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Prediction model to estimate presence of coronary artery disease: retrospective pooled analysis of existing cohorts

(2012) T. S. S. Genders et al.   BMJ-British Medical Journal

A clinical prediction rule for the diagnosis of coronary artery disease: validation, updating, and extension

(2011) T. S. S. Genders et al.   EUROPEAN HEART JOURNAL

SCCT guidelines for the interpretation and reporting of coronary computed tomographic angiography

(2009) Gilbert L. Raff et al.   Journal of Cardiovascular Computed Tomography