Immunologic mechanisms of seasonal influenza vaccination administered by microneedle patch from a randomized phase I trial

The potential role of using vaccine patches to induce immunity: platform and pathways to innovation and commercialization

(2020) Kamran Badizadegan et al.   Expert Review of Vaccines

Safety, tolerability, and immunogenicity of influenza vaccination with a high-density microarray patch: Results from a randomized, controlled phase I clinical trial

(2020) Angus H. Forster et al.   PLOS MEDICINE

HAI and NAI titer correlates of inactivated and live attenuated influenza vaccine efficacy

(2019) Peter B Gilbert et al.   BMC INFECTIOUS DISEASES

Pre-existing anti-neuraminidase antibodies are associated with shortened duration of influenza A (H1N1)pdm virus shedding and illness in naturally infected adults

(2019) Hannah E Maier et al.   CLINICAL INFECTIOUS DISEASES

A Universal Influenza Vaccine: The Strategic Plan for the National Institute of Allergy and Infectious Diseases

(2018) Emily J Erbelding et al.   JOURNAL OF INFECTIOUS DISEASES

Circulating T FH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity

(2018) Marios Koutsakos et al.   Science Translational Medicine

Human studies with microneedles for evaluation of their efficacy and safety

(2017) Thuy Trang Nguyen et al.   Expert Opinion on Drug Delivery

The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trial

(2017) Nadine G Rouphael et al.   LANCET

Influenza vaccines differentially regulate the interferon response in human dendritic cell subsets

(2017) Shruti Athale et al.   Science Translational Medicine

Potency of whole virus particle and split virion vaccines using dissolving microneedle against challenges of H1N1 and H5N1 influenza viruses in mice

(2017) Akihiro Nakatsukasa et al.   VACCINE

Engineering Microneedle Patches for Vaccination and Drug Delivery to Skin

(2017) Mark R. Prausnitz   Annual Review of Chemical and Biomolecular Engineering

Analysis of Anti-Influenza Virus Neuraminidase Antibodies in Children, Adults, and the Elderly by ELISA and Enzyme Inhibition: Evidence for Original Antigenic Sin

(2017) Madhusudan Rajendran et al.   mBio

Microneedle patch for immunization of immunocompromised hosts

(2017) Nadine G. Rouphael et al.   Oncotarget

Fluzone® Intradermal Quadrivalent Influenza Vaccine

(2016) Corwin A. Robertson et al.   Expert Review of Vaccines

Fluzone® High-Dose Influenza Vaccine

(2016) Corwin A. Robertson et al.   Expert Review of Vaccines

Evaluation of Antihemagglutinin and Antineuraminidase Antibodies as Correlates of Protection in an Influenza A/H1N1 Virus Healthy Human Challenge Model

(2016) Matthew J. Memoli et al.   mBio

The success of microneedle-mediated vaccine delivery into skin

(2016) Sarah Marshall et al.   Human Vaccines & Immunotherapeutics

ICOS+PD-1+CXCR3+ T follicular helper cells contribute to the generation of high-avidity antibodies following influenza vaccination

(2016) Salah-Eddine Bentebibel et al.   Scientific Reports

Clinical study and stability assessment of a novel transcutaneous influenza vaccination using a dissolving microneedle patch

(2015) Sachiko Hirobe et al.   BIOMATERIALS

Antibody to Influenza Virus Neuraminidase: An Independent Correlate of Protection

(2015) Arnold S. Monto et al.   JOURNAL OF INFECTIOUS DISEASES

An economic model assessing the value of microneedle patch delivery of the seasonal influenza vaccine

(2015) Bruce Y. Lee et al.   VACCINE

Enhanced immune responses by skin vaccination with influenza subunit vaccine in young hosts

(2015) Dimitrios G. Koutsonanos et al.   VACCINE

Improved immunogenicity of individual influenza vaccine components delivered with a novel dissolving microneedle patch stable at room temperature

(2015) Elena V. Vassilieva et al.   Drug Delivery and Translational Research

In the Shadow of Hemagglutinin: A Growing Interest in Influenza Viral Neuraminidase and Its Role as a Vaccine Antigen

(2014) Teddy Wohlbold et al.   Viruses-Basel

Nine μg intradermal influenza vaccine and 15 μg intramuscular influenza vaccine induce similar cellular and humoral immune responses in adults

(2014) Nolwenn Nougarede et al.   Human Vaccines & Immunotherapeutics

Long-Term Protective Immunity from an Influenza Virus-Like Particle Vaccine Administered with a Microneedle Patch

(2013) Fu-Shi Quan et al.   Clinical and Vaccine Immunology

Antibody Correlates and Predictors of Immunity to Naturally Occurring Influenza in Humans and the Importance of Antibody to the Neuraminidase

(2013) Robert B. Couch et al.   JOURNAL OF INFECTIOUS DISEASES

Cellular immune correlates of protection against symptomatic pandemic influenza

(2013) Saranya Sridhar et al.   NATURE MEDICINE

Induction of ICOS+CXCR3+CXCR5+ TH Cells Correlates with Antibody Responses to Influenza Vaccination

(2013) S.-E. Bentebibel et al.   Science Translational Medicine

A Meta-analysis of intradermal versus intramuscular influenza vaccines: Immunogenicity and Adverse Events

(2012) Fawziah Marra et al.   Influenza and Other Respiratory Viruses

Label-free mass spectrometry-based quantification of hemagglutinin and neuraminidase in influenza virus preparations and vaccines

(2012) Melkamu Getie-Kebtie et al.   Influenza and Other Respiratory Viruses

Oligomeric Recombinant H5 HA1 Vaccine Produced in Bacteria Protects Ferrets from Homologous and Heterologous Wild-Type H5N1 Influenza Challenge and Controls Viral Loads Better than Subunit H5N1 Vaccine by Eliciting High-Affinity Antibodies

(2012) S. Verma et al.   JOURNAL OF VIROLOGY

Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans

(2012) Tom M Wilkinson et al.   NATURE MEDICINE

Survey of the prevalence of immunization non-compliance due to needle fears in children and adults

(2012) Anna Taddio et al.   VACCINE

Recombinant HA1 produced in E. coli forms functional oligomers and generates strain-specific SRID potency antibodies for pandemic influenza vaccines

(2011) Surender Khurana et al.   VACCINE

Dose sparing enabled by skin immunization with influenza virus-like particle vaccine using microneedles

(2010) Fu-Shi Quan et al.   JOURNAL OF CONTROLLED RELEASE

Bacterial HA1 Vaccine against Pandemic H5N1 Influenza Virus: Evidence of Oligomerization, Hemagglutination, and Cross-Protective Immunity in Ferrets

(2010) S. Khurana et al.   JOURNAL OF VIROLOGY

Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes

(2010) Ana Clara Monsalvo et al.   NATURE MEDICINE

Properly Folded Bacterially Expressed H1N1 Hemagglutinin Globular Head and Ectodomain Vaccines Protect Ferrets against H1N1 Pandemic Influenza Virus

(2010) Surender Khurana et al.   PLoS One

Hemagglutinin-Pseudotyped Green Fluorescent Protein-Expressing Influenza Viruses for the Detection of Influenza Virus Neutralizing Antibodies

(2009) L. Martinez-Sobrido et al.   JOURNAL OF VIROLOGY

Intradermal, epidermal and transcutaneous vaccination: from immunology to clinical practice

(2008) Jean-François Nicolas et al.   Expert Review of Vaccines

Influence of Prior Influenza Vaccination on Antibody and B-Cell Responses

(2008) Sanae Sasaki et al.   PLoS One

Baseline Levels of Influenza-Specific CD4 Memory T-Cells Affect T-Cell Responses to Influenza Vaccines

(2008) Xiao-Song He et al.   PLoS One