Activation of Nrf2/HO-1 signaling: An important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular endothelial cells from oxidative stress
出版年份 2021 全文链接
标题
Activation of Nrf2/HO-1 signaling: An important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular endothelial cells from oxidative stress
作者
关键词
Atherosclerosis, Nrf2/HO-1 signaling, Vascular endothelial cells, Oxidative stress, Herbal medicine, Molecular mechanism
出版物
Journal of Advanced Research
Volume -, Issue -, Pages -
出版商
Elsevier BV
发表日期
2021-07-06
DOI
10.1016/j.jare.2021.06.023
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Early events in endothelial flow sensing
- (2021) Keiichiro Tanaka et al. Cytoskeleton
- Allicin alleviates inflammation of diabetic macroangiopathy via the Nrf2 and NF-kB pathway
- (2020) Chang-ling Li et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Sulforaphane attenuates angiotensin II-induced human umbilical vein endothelial cell injury by modulating ROS-mediated mitochondrial signaling
- (2020) M Zhang et al. HUMAN & EXPERIMENTAL TOXICOLOGY
- The potential effect of imatinib against hypercholesterolemia induced atherosclerosis, endothelial dysfunction and hepatic injury in rabbits
- (2020) Nora A. Ashry et al. LIFE SCIENCES
- Maslinic Acid Ameliorates Inflammation via the Downregulation of NF-κB and STAT-1
- (2020) Wonhwa Lee et al. Antioxidants
- Thrombospondin‐5 and fluvastatin promote angiogenesis and are protective against endothelial cell apoptosis
- (2020) Furqan Muqri et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Ubiquinol Ameliorates Endothelial Dysfunction in Subjects with Mild-to-Moderate Dyslipidemia: A Randomized Clinical Trial
- (2020) Jacopo Sabbatinelli et al. Nutrients
- The Role of Estrogen Receptors in Cardiovascular Disease
- (2020) Laila Aryan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The role of endothelial shear stress on haemodynamics, inflammation, coagulation and glycocalyx during sepsis
- (2020) Florea Lupu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Astragaloside IV Protects Against Oxidized Low-Density Lipoprotein (ox-LDL)-Induced Endothelial Cell Injury by Reducing Oxidative Stress and Inflammation
- (2019) Zhongsheng Zhu et al. MEDICAL SCIENCE MONITOR
- Beneficial Effects of Citrus Flavonoids on Cardiovascular and Metabolic Health
- (2019) Ayman M. Mahmoud et al. Oxidative Medicine and Cellular Longevity
- Endothelial SIRT6 Is Vital to Prevent Hypertension and Associated Cardiorenal Injury Through Targeting Nkx3.2-GATA5 Signaling
- (2019) Jian Guo et al. CIRCULATION RESEARCH
- Z-Ligustilide protects vascular endothelial cells from oxidative stress and rescues high fat diet-induced atherosclerosis by activating multiple NRF2 downstream genes
- (2019) Yao Zhu et al. ATHEROSCLEROSIS
- Vanillic acid alleviates palmitic acid‐induced oxidative stress in human umbilical vein endothelial cells via Adenosine Monophosphate‐Activated Protein Kinase signaling pathway
- (2019) Wen‐Fang Ma et al. JOURNAL OF FOOD BIOCHEMISTRY
- Cytoprotective effects of euxanthone against ox-LDL-induced endothelial cell injury is mediated via Nrf2
- (2019) Shengnan Li et al. LIFE SCIENCES
- Activation of Nrf2/HO-1 Pathway and Human Atherosclerotic Plaque Vulnerability:an In Vitro and In Vivo Study
- (2019) Fiorelli et al. Cells
- The Protective Role of Heme Oxygenase-1 in Atherosclerotic Diseases
- (2019) Yoshimi Kishimoto et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Xanthoangelol prevents ox-LDL-induced endothelial cell injury by activating Nrf2/ARE signaling
- (2019) Rui Yan et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Protective effects of phenylpropanoids and phenylpropanoid-rich essential oils on the cardiovascular system
- (2019) Jorge Alves Silva et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Astragalus polysaccharide alleviates H2O2-triggered oxidative injury in human umbilical vein endothelial cells via promoting KLF2
- (2019) Dongtao Li et al. Artificial Cells Nanomedicine and Biotechnology
- Salicin prevents TNF-α-induced cellular senescence in human umbilical vein endothelial cells (HUVECs)
- (2019) Fei Guo et al. Artificial Cells Nanomedicine and Biotechnology
- Reduced NRF2 expression suppresses endothelial progenitor cell function and induces senescence during aging
- (2019) Ruiyun Wang et al. Aging-US
- Apigenin and its methylglyoxal-adduct inhibit advanced glycation end products-induced oxidative stress and inflammation in endothelial cells
- (2019) Qian Zhou et al. BIOCHEMICAL PHARMACOLOGY
- Phthalides, senkyunolide A and ligustilide, show immunomodulatory effect in improving atherosclerosis, through inhibiting AP-1 and NF-κB expression
- (2019) Wei Lei et al. BIOMEDICINE & PHARMACOTHERAPY
- Rice Bran Phenolic Compounds Regulate Genes Associated with Antioxidant and Anti-Inflammatory Activity in Human Umbilical Vein Endothelial Cells with Induced Oxidative Stress
- (2019) Nancy Saji et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- MicroRNA-24 inhibits the oxidative stress induced by vascular injury by activating the Nrf2/Ho-1 signaling pathway
- (2019) Jing Zhang et al. ATHEROSCLEROSIS
- Naringenin-induced HO-1 ameliorates high glucose or free fatty acids-associated apoptosis via PI3K and JNK/Nrf2 pathways in human umbilical vein endothelial cells
- (2019) Jian Feng et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- The traditional uses, phytochemistry, pharmacology and toxicology of Cinnamomi ramulus : a review
- (2019) Jia Liu et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Medically Useful Plant Terpenoids: Biosynthesis, Occurrence, and Mechanism of Action
- (2019) Matthew E. Bergman et al. MOLECULES
- Protective effects of oxymatrine on homocysteine-induced endothelial injury: Involvement of mitochondria-dependent apoptosis and Akt-eNOS-NO signaling pathways
- (2019) Bo Wu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Nitric Oxide Signaling and Atherothrombosis Redux
- (2018) Joseph Loscalzo CIRCULATION
- Epigallocatechin-3-gallate attenuates microcystin-LR-induced apoptosis in human umbilical vein endothelial cells through activation of the NRF2/HO-1 pathway
- (2018) Jun Shi et al. ENVIRONMENTAL POLLUTION
- Corynoline Exhibits Anti-inflammatory Effects in Lipopolysaccharide (LPS)-Stimulated Human Umbilical Vein Endothelial Cells through Activating Nrf2
- (2018) Bin Liu et al. INFLAMMATION
- Biological Activities of Stilbenoids
- (2018) Bolanle Akinwumi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The feedback loop of “EMMPRIN/NF-κB” worsens atherosclerotic plaque via suppressing autophagy in macrophage
- (2018) Xing Liang et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Trigonelline inhibits intestinal microbial metabolism of choline and its associated cardiovascular risk
- (2018) Siraj Anwar et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Oxidative stress and cardiovascular disease: new insights
- (2018) Pasquale Pignatelli et al. Kardiologia Polska
- ROS signaling and ER stress in cardiovascular disease
- (2018) Cristhiaan D. Ochoa et al. MOLECULAR ASPECTS OF MEDICINE
- Ligustilide attenuates vascular inflammation and activates Nrf2/HO-1 induction and, NO synthesis in HUVECs
- (2018) Eun Sik Choi et al. PHYTOMEDICINE
- Endothelial nitric oxide synthase overexpressing human early outgrowth cells inhibit coronary artery smooth muscle cell migration through paracrine functions
- (2018) Sergio Guber et al. Scientific Reports
- Salidroside Protects Against Advanced Glycation End Products-Induced Vascular Endothelial Dysfunction
- (2018) Peng Zhang et al. MEDICAL SCIENCE MONITOR
- Zedoarondiol Attenuates Endothelial Cells Injury Induced by Oxidized Low-Density Lipoprotein via Nrf2 Activation
- (2018) Huimin Mao et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Protocatechuic Acid Ameliorated Palmitic-Acid-Induced Oxidative Damage in Endothelial Cells through Activating Endogenous Antioxidant Enzymes via an Adenosine-Monophosphate-Activated-Protein-Kinase-Dependent Pathway
- (2018) Lin Han et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Klotho protein inhibits H2O2-induced oxidative injury in endothelial Cells via regulation of PI3K/Akt/Nrf2/HO-1 Pathways.
- (2018) wei cui et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- Activation of Nrf2 by Phloretin Attenuates Palmitic Acid-Induced Endothelial Cell Oxidative Stress via AMPK-Dependent Signaling
- (2018) Qing Yang et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Platelet Microparticles Mediate Glomerular Endothelial Injury in Early Diabetic Nephropathy
- (2018) Yang Zhang et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Nepeta angustifolia attenuates responses to vascular inflammation in high glucose-induced human umbilical vein endothelial cells through heme oxygenase-1 induction
- (2018) Shan Huang et al. JOURNAL OF ETHNOPHARMACOLOGY
- Bioactivity: phenylpropanoids’ best kept secret
- (2018) Bartel Vanholme et al. CURRENT OPINION IN BIOTECHNOLOGY
- Celastrol attenuates angiotensin II mediated human umbilical vein endothelial cells damage through activation of Nrf2/ERK1/2/Nox2 signal pathway
- (2017) Miao Li et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Schisandrin B inhibits LPS-induced inflammatory response in human umbilical vein endothelial cells by activating Nrf2
- (2017) Qiuning Lin et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Pterostilbene protects against uraemia serum-induced endothelial cell damage via activation of Keap1/Nrf2/HO-1 signaling
- (2017) Zhi-Wei Chen et al. INTERNATIONAL UROLOGY AND NEPHROLOGY
- GW28-e0646 Echinacoside protects against high glucose-induced oxidative stress in vascular endothelial cells through Nrf2/HO-1 dependent pathway
- (2017) Jiahong Xue et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Epigallocatechin-3-Gallate Ameliorates Angiotensin II-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells through the Activation of Nrf2/Caspase-3 Signaling
- (2017) Xiuli Zhou et al. JOURNAL OF VASCULAR RESEARCH
- (-)-7(S)-hydroxymatairesinol protects against tumor necrosis factor-α-mediated inflammation response in endothelial cells by blocking the MAPK/NF-κB and activating Nrf2/HO-1
- (2017) Di Yang et al. PHYTOMEDICINE
- Molecular Sensors of Blood Flow in Endothelial Cells
- (2017) Sara Baratchi et al. TRENDS IN MOLECULAR MEDICINE
- PotentIn VitroProtection Against PM2.5-Caused ROS Generation and Vascular Permeability by Long-Term Pretreatment withGanoderma tsugae
- (2016) Chia-Yi Tseng et al. AMERICAN JOURNAL OF CHINESE MEDICINE
- Withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway
- (2016) Karen Heyninck et al. BIOCHEMICAL PHARMACOLOGY
- Low nanomolar caffeic acid attenuates high glucose-induced endothelial dysfunction in primary human umbilical-vein endothelial cells by affecting NF-κB and Nrf2 pathways
- (2016) Deborah Fratantonio et al. BIOFACTORS
- Nanoformulation of curcumin protects HUVEC endothelial cells against ionizing radiation and suppresses their adhesion to monocytes: potential in prevention of radiation-induced atherosclerosis
- (2016) Behrooz Soltani et al. BIOTECHNOLOGY LETTERS
- Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism
- (2016) Agnieszka Loboda et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis
- (2016) Michael A. Gimbrone et al. CIRCULATION RESEARCH
- Andrographolide inhibits hypoxia-induced HIF-1α-driven endothelin 1 secretion by activating Nrf2/HO-1 and promoting the expression of prolyl hydroxylases 2/3 in human endothelial cells
- (2016) Hung-Chih Lin et al. ENVIRONMENTAL TOXICOLOGY
- Cardiovascular disease in Europe: epidemiological update 2016
- (2016) Nick Townsend et al. EUROPEAN HEART JOURNAL
- 2-Methoxycinnamaldehyde inhibits the TNF-α-induced proliferation and migration of human aortic smooth muscle cells
- (2016) Young-Hee Jin et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Garlic and Heart Disease
- (2016) Ravi Varshney et al. JOURNAL OF NUTRITION
- Salidroside Suppresses HUVECs Cell Injury Induced by Oxidative Stress through Activating the Nrf2 Signaling Pathway
- (2016) Yao Zhu et al. MOLECULES
- ROS and ROS-Mediated Cellular Signaling
- (2016) Jixiang Zhang et al. Oxidative Medicine and Cellular Longevity
- Miltirone protects human EA.hy926 endothelial cells from oxidized low-density lipoprotein-derived oxidative stress via a heme oxygenase-1 and MAPK/Nrf2 dependent pathway
- (2016) Liu Zhang et al. PHYTOMEDICINE
- Equol Attenuates Atherosclerosis in Apolipoprotein E-Deficient Mice by Inhibiting Endoplasmic Reticulum Stress via Activation of Nrf2 in Endothelial Cells
- (2016) Ting Zhang et al. PLoS One
- Celery Seed Extract Blocks Peroxide Injury in Macrophages via Notch1/NF-κB Pathway
- (2015) Yanhong Si et al. AMERICAN JOURNAL OF CHINESE MEDICINE
- Cinnamaldehyde Prevents Endothelial Dysfunction Induced by High Glucose by Activating Nrf2
- (2015) Fang Wang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Endothelial Cell Metabolism in Normal and Diseased Vasculature
- (2015) Guy Eelen et al. CIRCULATION RESEARCH
- Lycopene inhibits cyclic strain-induced endothelin-1 expression through the suppression of reactive oxygen species generation and induction of heme oxygenase-1 in human umbilical vein endothelial cells
- (2015) Li-Chin Sung et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Statin-associated muscle symptoms: impact on statin therapy—European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management
- (2015) Erik S. Stroes et al. EUROPEAN HEART JOURNAL
- The Activation of Nrf2 and Its Downstream Regulated Genes Mediates the Antioxidative Activities of Xueshuan Xinmaining Tablet in Human Umbilical Vein Endothelial Cells
- (2015) Lingxin Xiong et al. Evidence-based Complementary and Alternative Medicine
- Modulation of oxidized-LDL receptor-1 (LOX1) contributes to the antiatherosclerosis effect of oleanolic acid
- (2015) Qixiao Jiang et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Eriodictyol Protects Endothelial Cells against Oxidative Stress-Induced Cell Death through Modulating ERK/Nrf2/ARE-Dependent Heme Oxygenase-1 Expression
- (2015) Seung Lee et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Epigallocatechin-3-Gallate Protects HUVECs from PM2.5-Induced Oxidative Stress Injury by Activating Critical Antioxidant Pathways
- (2015) Guang-Zhao Yang et al. MOLECULES
- Role of homocysteine in the development of cardiovascular disease
- (2015) Paul Ganguly et al. Nutrition Journal
- Antiinflammatory and antioxidant effects of H2O2 generated by natural sources in Il1β-treated human endothelial cells
- (2015) Alice Toniolo et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Palmitate-induced endothelial dysfunction is attenuated by cyanidin-3-O-glucoside through modulation of Nrf2/Bach1 and NF-κB pathways
- (2015) D. Fratantonio et al. TOXICOLOGY LETTERS
- Association Between Heme Oxygenase 1 Gene Promoter Polymorphisms and Susceptibility to Coronary Artery Disease: A HuGE Review and Meta-Analysis
- (2014) Huaiyu Qiao et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Andrographolide inhibits TNFα-induced ICAM-1 expression via suppression of NADPH oxidase activation and induction of HO-1 and GCLM expression through the PI3K/Akt/Nrf2 and PI3K/Akt/AP-1 pathways in human endothelial cells
- (2014) Chia-Yang Lu et al. BIOCHEMICAL PHARMACOLOGY
- Bioavailability of anthocyanins
- (2014) Jim Fang DRUG METABOLISM REVIEWS
- Insulin resistance and hyperglycaemia in cardiovascular disease development
- (2014) Markku Laakso et al. Nature Reviews Endocrinology
- Genistein Inhibits ox-LDL-induced VCAM-1, ICAM-1 and MCP-1 Expression of HUVECs Through Heme Oxygenase-1
- (2013) Hua-ping Zhang et al. ARCHIVES OF MEDICAL RESEARCH
- Ionizing radiation and atherosclerosis: Current knowledge and future challenges
- (2013) Andrea Borghini et al. ATHEROSCLEROSIS
- The absence of macrophage Nrf2 promotes early atherogenesis
- (2013) Anna-Kaisa Ruotsalainen et al. CARDIOVASCULAR RESEARCH
- The flavanol (-)-epicatechin and its metabolites protect against oxidative stress in primary endothelial cells via a direct antioxidant effect
- (2013) Erik J.B. Ruijters et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Botany, phytochemistry, pharmacology, and potential application of Polygonum cuspidatum Sieb.et Zucc.: A review
- (2013) Wei Peng et al. JOURNAL OF ETHNOPHARMACOLOGY
- Rapid health transition in China, 1990–2010: findings from the Global Burden of Disease Study 2010
- (2013) Gonghuan Yang et al. LANCET
- Isothiocyanates protect against oxidized LDL-induced endothelial dysfunction by upregulating Nrf2-dependent antioxidation and suppressing NFκB activation
- (2013) Chin-Shiu Huang et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Cyanidin-3-O-glucoside counters the response to TNF-alpha of endothelial cells by activating Nrf2 pathway
- (2013) Antonio Speciale et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Sauchinone from Saururus chinensis protects vascular inflammation by heme oxygenase-1 induction in human umbilical vein endothelial cells
- (2013) Bin Li et al. PHYTOMEDICINE
- Ginsenoside Rg1 reduces toxicity of PM2.5 on human umbilical vein endothelial cells by upregulating intracellular antioxidative state
- (2012) Cai-ping Li et al. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
- Anthocyanins protect human endothelial cells from mild hyperoxia damage through modulation of Nrf2 pathway
- (2012) Francesco Cimino et al. Genes and Nutrition
- Prunella vulgaris Suppresses HG-Induced Vascular Inflammation via Nrf2/HO-1/eNOS Activation
- (2012) Sun Mi Hwang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Up-regulation of Heme Oxygenase-1 by Korean Red Ginseng Water Extract as a Cytoprotective Effect in Human Endothelial Cells
- (2012) Ha-Na Yang et al. Journal of Ginseng Research
- The Role of Nitric Oxide on Endothelial Function
- (2011) Dimitris Tousoulis et al. Current Vascular Pharmacology
- Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis
- (2011) Stefan Freigang et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Fisetin induces Nrf2-mediated HO-1 expression through PKC-δ and p38 in human umbilical vein endothelial cells
- (2011) Seung Eun Lee et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Epigallocatechin-gallate stimulates NF-E2-related factor and heme oxygenase-1 via caveolin-1 displacement
- (2011) Yuanyuan Zheng et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- NF-E2–Related Factor 2 Promotes Atherosclerosis by Effects on Plasma Lipoproteins and Cholesterol Transport That Overshadow Antioxidant Protection
- (2010) Berenice Barajas et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Ferulic Acid Protects Human Umbilical Vein Endothelial Cells from Radiation Induced Oxidative Stress by Phosphatidylinositol 3-Kinase and Extracellular Signal-Regulated Kinase Pathways
- (2010) Zeng-Chun Ma et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Artemisinin inhibits extracellular matrix metalloproteinase inducer (EMMPRIN) and matrix metalloproteinase-9 expression via a protein kinase Cδ/p38/extracellular signal-regulated kinase pathway in phorbol myristate acetate-induced THP-1 macrophages
- (2010) Yue Wang et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Isolating a Cytoprotective Compound fromGanoderma tsugae: Effects on Induction of Nrf-2-Related Genes in Endothelial Cells
- (2009) Yu-Shan WEI et al. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- New Antithrombotic Drugs
- (2009) P L Gross et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
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