标题
PFKFB3 Inhibition Impairs Erlotinib-Induced Autophagy in NSCLCs
作者
关键词
-
出版物
Cells
Volume 10, Issue 7, Pages 1679
出版商
MDPI AG
发表日期
2021-07-05
DOI
10.3390/cells10071679
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Inhibition of PFKFB3 induces cell death and synergistically enhances chemosensitivity in endometrial cancer
- (2021) Yinan Xiao et al. ONCOGENE
- Oxidative stress-mediated AMPK inactivation determines the high susceptibility of LKB1-mutant NSCLC cells to glucose starvation
- (2021) Yi Ren et al. FREE RADICAL BIOLOGY AND MEDICINE
- Cancer statistics, 2020
- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System
- (2020) Jingyue Jia et al. MOLECULAR CELL
- Acquired resistance to osimertinib in patients with non-small-cell lung cancer: mechanisms and clinical outcomes
- (2020) Yuxin Mu et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Role of PARP1-mediated autophagy in EGFR-TKI resistance in non-small cell lung cancer
- (2020) Zhimin Zhang et al. Scientific Reports
- Protective autophagy decreases osimertinib cytotoxicity through regulation of stem cell-like properties in lung cancer
- (2019) Li Li et al. CANCER LETTERS
- Mitochondrial respiratory chain deficiency inhibits lysosomal hydrolysis
- (2019) Lorena Fernandez-Mosquera et al. Autophagy
- Increased 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 activity in response to EGFR signaling contributes to non-small cell lung cancer cell survival
- (2019) Nadiia Lypova et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Role of tumor and host autophagy in cancer metabolism
- (2019) Laura Poillet-Perez et al. GENES & DEVELOPMENT
- Intrinsic resistance to EGFR-Tyrosine Kinase Inhibitors in EGFR-Mutant Non-Small Cell Lung Cancer: Differences and Similarities with Acquired Resistance
- (2019) Santoni-Rugiu et al. Cancers
- The Lysosome Signaling Platform: Adapting With the Times
- (2019) Subothan Inpanathan et al. Frontiers in Cell and Developmental Biology
- PAQR3 suppresses the growth of non-small cell lung cancer cells via modulation of EGFR-mediated autophagy
- (2019) Qianqian Cao et al. Autophagy
- PFKFB3 inhibition reprograms malignant pleural mesothelioma to nutrient stress-induced macropinocytosis and ER stress as independent binary adaptive responses
- (2019) Sayantani Sarkar Bhattacharya et al. Cell Death & Disease
- Targeting Autophagy in Cancer: Recent Advances and Future Directions
- (2019) Ravi K. Amaravadi et al. Cancer Discovery
- Targeting Autophagy for Overcoming Resistance to Anti-EGFR Treatments
- (2019) Yoojung Kwon et al. Cancers
- PFKFB3 Inhibition Attenuates Oxaliplatin-Induced Autophagy and Enhances Its Cytotoxicity in Colon Cancer Cells
- (2019) Siyuan Yan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 expression
- (2019) Alyssa La Belle Flynn et al. Nature Communications
- Measuring autophagosome flux
- (2018) Andre du Toit et al. Autophagy
- Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion
- (2018) Mario Mauthe et al. Autophagy
- Enhanced glycolysis supports cell survival in EGFR-mutant lung adenocarcinoma by inhibiting autophagy-mediated EGFR degradation
- (2018) Ji Hye Kim et al. CANCER RESEARCH
- Autophagy Modulation in Cancer: Current Knowledge on Action and Therapy
- (2018) Mija Marinković et al. Oxidative Medicine and Cellular Longevity
- Therapeutic targeting of PFKFB3 with a novel glycolytic inhibitor PFK158 promotes lipophagy and chemosensitivity in gynecologic cancers
- (2018) Susmita Mondal et al. INTERNATIONAL JOURNAL OF CANCER
- AZD9291 promotes autophagy and inhibits PI3K/Akt pathway in NSCLC cancer cells
- (2018) Zhirui Zhang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The clinical significance of autophagy in patients with non small cell lung cancer.
- (2018) Nariyasu Nakashima et al. JOURNAL OF CLINICAL ONCOLOGY
- AMPK contributes to autophagosome maturation and lysosomal fusion
- (2018) Minsu Jang et al. Scientific Reports
- Alternative drug sensitivity metrics improve preclinical cancer pharmacogenomics
- (2017) Marc Hafner et al. NATURE BIOTECHNOLOGY
- Influence of autophagy on the efficacy of radiotherapy
- (2017) Shing Yau Tam et al. Radiation Oncology
- Oncogenic driver mutations, treatment, and EGFR-TKI resistance in a Caucasian population with non-small cell lung cancer: survival in clinical practice
- (2017) Martin Faehling et al. Oncotarget
- 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase isoform 3 spatially mediates autophagy through the AMPK signaling pathway
- (2017) Siyuan Yan et al. Oncotarget
- EGFR Family Members’ Regulation of Autophagy Is at a Crossroads of Cell Survival and Death in Cancer
- (2017) Elizabeth Henson et al. Cancers
- Inhibition of 6-phosphofructo-2-kinase (PFKFB3) suppresses glucose metabolism and the growth of HER2+ breast cancer
- (2016) Julie O’Neal et al. BREAST CANCER RESEARCH AND TREATMENT
- A Kinase-Independent Role for EGF Receptor in Autophagy Initiation
- (2015) Xiaojun Tan et al. CELL
- Dysregulated metabolism contributes to oncogenesis
- (2015) Matthew D. Hirschey et al. SEMINARS IN CANCER BIOLOGY
- Targeting molecular addictions in cancer
- (2014) I Vivanco BRITISH JOURNAL OF CANCER
- Evaluation of acridine orange, LysoTracker Red, and quinacrine as fluorescent probes for long-term tracking of acidic vesicles
- (2014) Agnieszka Pierzyńska-Mach et al. CYTOMETRY PART A
- Activation of AMP-activated protein kinase sensitizes lung cancer cells and H1299 xenografts to erlotinib
- (2014) Helen J. Hülsmann et al. LUNG CANCER
- Control of Glycolytic Flux by AMP-Activated Protein Kinase in Tumor Cells Adapted to Low pH
- (2014) Erin E. Mendoza et al. Translational Oncology
- EGFR inhibitors and autophagy in cancer treatment
- (2014) Jie Cui et al. TUMOR BIOLOGY
- Glucose-starved Cells Do Not Engage in Prosurvival Autophagy
- (2013) Silvia Ramírez-Peinado et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Increased Concentrations of Fructose 2,6-Bisphosphate Contribute to the Warburg Effect in Phosphatase and Tensin Homolog (PTEN)-deficient Cells
- (2013) Lucía Cordero-Espinoza et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Autophagy Inhibitor Chloroquine Overcomes the Innate Resistance of Wild-Type EGFR Non-Small-Cell Lung Cancer Cells to Erlotinib
- (2013) Yiyu Zou et al. Journal of Thoracic Oncology
- Enhanced autophagy is required for survival in EGFR-independent EGFR-mutant lung adenocarcinoma cells
- (2013) Yuji Sakuma et al. LABORATORY INVESTIGATION
- Erlotinib-induced autophagy in epidermal growth factor receptor mutated non-small cell lung cancer
- (2013) Yuan-yuan Li et al. LUNG CANCER
- Glycolysis Inhibition Sensitizes Non-Small Cell Lung Cancer with T790M Mutation to Irreversible EGFR Inhibitors via Translational Suppression of Mcl-1 by AMPK Activation
- (2013) S. M. Kim et al. MOLECULAR CANCER THERAPEUTICS
- Suppression of basal autophagy reduces lung cancer cell proliferation and enhances caspase-dependent and -independent apoptosis by stimulating ROS formation
- (2012) Vitaliy O. Kaminskyy et al. Autophagy
- Guidelines for the use and interpretation of assays for monitoring autophagy
- (2012) Daniel J. Klionsky et al. Autophagy
- EGFR tyrosine kinase inhibition induces autophagy in cancer cells
- (2012) Christopher Fung et al. CANCER BIOLOGY & THERAPY
- Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
- (2012) Patrick S. Ward et al. CANCER CELL
- Roles of autophagy in cetuximab-mediated cancer therapy against EGFR
- (2010) Xinqun Li et al. Autophagy
- Survival of Cancer Cells Is Maintained by EGFR Independent of Its Kinase Activity
- (2008) Zhang Weihua et al. CANCER CELL
- Autophagy and multivesicular bodies: two closely related partners
- (2008) C M Fader et al. CELL DEATH AND DIFFERENTIATION
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