Predictive and Prognostic Biomarker Identification in a Large Cohort of Androgen Receptor-Positive Salivary Duct Carcinoma Patients Scheduled for Combined Androgen Blockade

RNA Based Approaches to Profile Oncogenic Pathways From Low Quantity Samples to Drive Precision Oncology Strategies

(2021) Anja van de Stolpe et al.   Frontiers in Genetics

Salivary duct carcinoma: Updates in histology, cytology, molecular biology, and treatment

(2020) Masato Nakaguro et al.   CANCER CYTOPATHOLOGY

ER and PI3K Pathway Activity in Primary ER Positive Breast Cancer Is Associated with Progression-Free Survival of Metastatic Patients under First-Line Tamoxifen

(2020) Anieta M. Sieuwerts et al.   Cancers

Oestrogen receptor pathway activity is associated with outcome in endometrial cancer

(2020) Willem Jan van Weelden et al.   BRITISH JOURNAL OF CANCER

Systemic therapy in the management of recurrent or metastatic salivary duct carcinoma: A systematic review

(2020) M.J.M. Uijen et al.   CANCER TREATMENT REVIEWS

EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer. Part II—2020 Update: Treatment of Relapsing and Metastatic Prostate Cancer

(2020) Philip Cornford et al.   EUROPEAN UROLOGY

Signal Transduction Pathway Activity in High-Grade, Serous Ovarian Carcinoma Reveals a More Favorable Prognosis in Tumors with Low PI3K and High NF-κB Pathway Activity: A Novel Approach to a Long-Standing Enigma

(2020) Laura van Lieshout et al.   Cancers

Dutasteride combined with androgen receptor antagonists inhibit glioblastoma U87 cell metabolism, proliferation, and invasion capacity: Androgen regulation

(2020) M. Orozco et al.   STEROIDS

Quantitative Measurement of Functional Activity of the PI3K Signaling Pathway in Cancer

(2019) Anja van de Stolpe   Cancers

Enabling precision medicine by unravelling disease pathophysiology: quantifying signal transduction pathway activity across cell and tissue types

(2019) Anja van de Stolpe et al.   Scientific Reports

A positive role of c-Myc in regulating androgen receptor and its splice variants in prostate cancer

(2019) Shanshan Bai et al.   ONCOGENE

A pivotal role of androgen signaling in Notch-responsive cells in prostate development, maturation, and regeneration

(2019) Joseph Aldahl et al.   DIFFERENTIATION

NOTCH signaling is activated in and contributes to resistance in enzalutamide-resistant prostate cancer cells

(2019) Elia Farah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic hallmarks of recurrent/metastatic adenoid cystic carcinoma

(2019) Allen S. Ho et al.   JOURNAL OF CLINICAL INVESTIGATION

First Line Androgen Deprivation Therapy vs. Chemotherapy for Patients With Androgen Receptor Positive Recurrent or Metastatic Salivary Gland Carcinoma—A Retrospective Study

(2019) Paul V. Viscuse et al.   Frontiers in Oncology

Advances and challenges in precision medicine in salivary gland cancer

(2019) Gerben Lassche et al.   CANCER TREATMENT REVIEWS

Estrogen Receptor pathway activity score to predict clinical response or resistance to neo-adjuvant endocrine therapy in primary breast cancer

(2019) Marcia A. Inda et al.   MOLECULAR CANCER THERAPEUTICS

Novel therapeutic targets in salivary duct carcinoma uncovered by comprehensive molecular profiling

(2019) Stacey M. Gargano et al.   Cancer Medicine

Prediction of clinical benefit from androgen deprivation therapy in salivary duct carcinoma patients

(2019) Wim Boxtel et al.   INTERNATIONAL JOURNAL OF CANCER

Assessment of Functional Phosphatidylinositol 3-Kinase Pathway Activity in Cancer Tissue Using Forkhead Box O Target Gene Expression in a Knowledge-Based Computational Model

(2018) Henk van Ooijen et al.   AMERICAN JOURNAL OF PATHOLOGY

A clinicopathological study and prognostic factor analysis of 177 salivary duct carcinoma patients from The Netherlands

(2018) Eline Boon et al.   INTERNATIONAL JOURNAL OF CANCER

Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Focused Update

(2018) Antonio C. Wolff et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase II Trial of Trastuzumab and Docetaxel in Patients With Human Epidermal Growth Factor Receptor 2–Positive Salivary Duct Carcinoma

(2018) Hideaki Takahashi et al.   JOURNAL OF CLINICAL ONCOLOGY

Androgen deprivation therapy for androgen receptor-positive advanced salivary duct carcinoma: A nationwide case series of 35 patients in The Netherlands

(2017) Eline Boon et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Activating NOTCH1 Mutations Define a Distinct Subgroup of Patients With Adenoid Cystic Carcinoma Who Have Poor Prognosis, Propensity to Bone and Liver Metastasis, and Potential Responsiveness to Notch1 Inhibitors

(2017) Renata Ferrarotto et al.   JOURNAL OF CLINICAL ONCOLOGY

Salivary duct carcinoma: An aggressive salivary gland malignancy with opportunities for targeted therapy

(2017) Nicole C. Schmitt et al.   ORAL ONCOLOGY

Clinical Outcomes and Prognostic Factors for Salivary Duct Carcinoma: A Multi-Institutional Analysis of 141 Patients

(2016) Kuninori Otsuka et al.   ANNALS OF SURGICAL ONCOLOGY

Notch signalling in context

(2016) Sarah J. Bray   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Clinical activity of androgen deprivation therapy in patients with metastatic/relapsed androgen receptor-positive salivary gland cancers

(2015) Laura D. Locati et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Biomarker: Predictive or Prognostic?

(2015) Karla V. Ballman   JOURNAL OF CLINICAL ONCOLOGY

Dutasteride and Enzalutamide Synergistically Suppress Prostate Tumor Cell Proliferation

(2015) Agus Rizal A.H. Hamid et al.   JOURNAL OF UROLOGY

Selection of Personalized Patient Therapy through the Use of Knowledge-Based Computational Models That Identify Tumor-Driving Signal Transduction Pathways

(2014) W. Verhaegh et al.   CANCER RESEARCH