FMR1 and AKT/mTOR Signaling in Human Granulosa Cells: Functional Interaction and Impact on Ovarian Response

FMR1 expression in human granulosa cells and variable ovarian response: control by epigenetic mechanisms

(2021) Julia Rehnitz et al.   MOLECULAR HUMAN REPRODUCTION

The Roles of FoxO Transcription Factors in Regulation of Bone Cells Function

(2020) Ma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

FOXO3 Is Expressed in Ovarian Tissues and Acts as an Apoptosis Initiator in Granulosa Cells of Chickens

(2019) Can Cui et al.   Biomed Research International

Advances in human primordial follicle activation and premature ovarian insufficiency

(2019) Emmalee Ford et al.   REPRODUCTION

The mTOR Pathway in Reproduction: From Gonadal Function to Developmental Coordination

(2019) Bibiana Correia et al.   REPRODUCTION

Role of mTOR Signaling in Female Reproduction

(2019) Zaixin Guo et al.   Frontiers in Endocrinology

FMR1 expression in human granulosa cells increases with exon 1 CGG repeat length depending on ovarian reserve

(2018) Julia Rehnitz et al.   Reproductive Biology and Endocrinology

Premature recruitment of oocyte pool and increased mTOR activity in Fmr1 knockout mice and reversal of phenotype with rapamycin

(2018) E. Mok-Lin et al.   Scientific Reports

Cumulus cells surrounding oocytes with high developmental competence exhibit down-regulation of phosphoinositol 1,3 kinase/protein kinase B (PI3K/AKT) signalling genes involved in proliferation and survival

(2017) P G Artini et al.   HUMAN REPRODUCTION

A putative role for anti-Müllerian hormone (AMH) in optimising ovarian reserve expenditure

(2017) Michael W Pankhurst   JOURNAL OF ENDOCRINOLOGY

Molecular Characterization of FMR1 Gene by TP-PCR in Women of Reproductive Age and Women with Premature Ovarian Insufficiency

(2017) Deepika Delsa Dean et al.   Molecular Diagnosis & Therapy

FMR1 and AKT/mTOR signalling pathways: potential functional interactions controlling folliculogenesis in human granulosa cells

(2017) Julia Rehnitz et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Fragile X-Associated Tremor/Ataxia Syndrome: From Molecular Pathogenesis to Development of Therapeutics

(2017) Ha Eun Kong et al.   Frontiers in Cellular Neuroscience

Fragile X-Associated Diminished Ovarian Reserve and Primary Ovarian Insufficiency from Molecular Mechanisms to Clinical Manifestations

(2017) Limor Man et al.   Frontiers in Molecular Neuroscience

Somatic overgrowth disorders of the PI3K/AKT/mTOR pathway & therapeutic strategies

(2016) Kim M. Keppler-Noreuil et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Activation of dormant follicles

(2016) Kazuhiro Kawamura et al.   CURRENT OPINION IN OBSTETRICS & GYNECOLOGY

ESHRE Guideline: management of women with premature ovarian insufficiency

(2016)   HUMAN REPRODUCTION

Genetics of primary ovarian insufficiency: new developments and opportunities

(2015) Yingying Qin et al.   HUMAN REPRODUCTION UPDATE

Evidence of an age-related correlation of ovarian reserve and FMR1 repeat number among women with “normal” CGG repeat status

(2015) Stephanie L. F. Gustin et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Involvement of FoxO1 in the effects of follicle-stimulating hormone on inhibition of apoptosis in mouse granulosa cells

(2014) M Shen et al.   Cell Death & Disease

Gonadal Expression of Foxo1, but Not Foxo3, Is Conserved in Diverse Mammalian Species1

(2013) Edward D. Tarnawa et al.   BIOLOGY OF REPRODUCTION

The role of Akt signalling in the mammalian ovary

(2013) Sandra Cecconi et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

FOXO1/3 Depletion in Granulosa Cells Alters Follicle Growth, Death and Regulation of Pituitary FSH

(2013) Zhilin Liu et al.   MOLECULAR ENDOCRINOLOGY

Fragile X and X-Linked Intellectual Disability: Four Decades of Discovery

(2012) Herbert A. Lubs et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Molecular control of oogenesis

(2012) Flor Sánchez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Fragile X premutation RNA is sufficient to cause primary ovarian insufficiency in mice

(2012) Cuiling Lu et al.   HUMAN MOLECULAR GENETICS

Follicular Growth and Atresia in Mammalian Ovaries: Regulation by Survival and Death of Granulosa Cells

(2012) Fuko MATSUDA et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Intracellular signalling during female gametogenesis

(2012) A.P. Sobinoff et al.   MOLECULAR HUMAN REPRODUCTION

FMRP targets distinct mRNA sequence elements to regulate protein expression

(2012) Manuel Ascano et al.   NATURE

Elevated Prevalence of 35-44 FMR1 Trinucleotide Repeats in Women With Diminished Ovarian Reserve

(2012) Lisa M. Pastore et al.   Reproductive Sciences

Variable expression of the Fragile X Mental Retardation 1 (FMR1) gene in patients with premature ovarian failure syndrome is not dependent on number of (CGG)n triplets in exon 1

(2011) J. Schuettler et al.   HUMAN REPRODUCTION

ESHRE consensus on the definition of 'poor response' to ovarian stimulation for in vitro fertilization: the Bologna criteria

(2011) A. P. Ferraretti et al.   HUMAN REPRODUCTION

What does it take to make a developmentally competent mammalian egg?

(2011) M. Zuccotti et al.   HUMAN REPRODUCTION UPDATE

Dysregulation of mTOR Signaling in Fragile X Syndrome

(2010) A. Sharma et al.   JOURNAL OF NEUROSCIENCE

Relevance of triple CGG repeats in the FMR1 gene to ovarian reserve

(2010) Norbert Gleicher et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Ovarian reserve determinations suggest new function of FMR1 (fragile X gene) in regulating ovarian ageing

(2010) Norbert Gleicher et al.   REPRODUCTIVE BIOMEDICINE ONLINE

The RNA-induced Silencing Complex: A Versatile Gene-silencing Machine

(2009) Ashley J. Pratt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S6K1 Phosphorylates and Regulates Fragile X Mental Retardation Protein (FMRP) with the Neuronal Protein Synthesis-dependent Mammalian Target of Rapamycin (mTOR) Signaling Cascade

(2008) Usha Narayanan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY