Pembrolizumab for patients with leptomeningeal metastasis from solid tumors: efficacy, safety, and cerebrospinal fluid biomarkers

Inflammatory leptomeningeal cytokines mediate COVID-19 neurologic symptoms in cancer patients

(2021) Jan Remsik et al.   CANCER CELL

The Network of Cytokines in Brain Metastases

(2021) Jawad Fares et al.   Cancers

Assessing aneuploidy with repetitive element sequencing

(2020) Christopher Douville et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pembrolizumab for management of patients with NSCLC and brain metastases: long-term results and biomarker analysis from a non-randomised, open-label, phase 2 trial

(2020) Sarah B Goldberg et al.   LANCET ONCOLOGY

Single-arm, open-label phase 2 trial of pembrolizumab in patients with leptomeningeal carcinomatosis

(2020) Priscilla K. Brastianos et al.   NATURE MEDICINE

The RANO Leptomeningeal Metastasis Group proposal to assess response to treatment: lack of feasibility and clinical utility and a revised proposal

(2019) Emilie Le Rhun et al.   NEURO-ONCOLOGY

Pembrolizumab plus trastuzumab in trastuzumab-resistant, advanced, HER2-positive breast cancer (PANACEA): a single-arm, multicentre, phase 1b–2 trial

(2019) Sherene Loi et al.   LANCET ONCOLOGY

1311OLong-term outcomes from the randomized phase II study of nivolumab (nivo) or nivo+ipilimumab (ipi) in patients (pts) with melanoma brain metastases (mets): Anti-PD1 brain collaboration (ABC)

(2019) G V Long et al.   ANNALS OF ONCOLOGY

Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis

(2019) Gonçalo Rodrigues et al.   NATURE CELL BIOLOGY

Osimertinib for Patients With Leptomeningeal Metastases Associated With EGFR T790M-Positive Advanced NSCLC: The AURA Leptomeningeal Metastases Analysis

(2019) Myung-Ju Ahn et al.   Journal of Thoracic Oncology

Combination nivolumab and ipilimumab or nivolumab alone in melanoma brain metastases: a multicentre randomised phase 2 study

(2018) Georgina V Long et al.   LANCET ONCOLOGY

Detection of aneuploidy in patients with cancer through amplification of long interspersed nucleotide elements (LINEs)

(2018) Christopher Douville et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of Baseline Steroids on Efficacy of Programmed Cell Death-1 and Programmed Death-Ligand 1 Blockade in Patients With Non–Small-Cell Lung Cancer

(2018) Kathryn C. Arbour et al.   JOURNAL OF CLINICAL ONCOLOGY

Therapy of leptomeningeal metastasis in solid tumors

(2016) F. Mack et al.   CANCER TREATMENT REVIEWS

Leptomeningeal metastases: a RANO proposal for response criteria

(2016) Marc Chamberlain et al.   NEURO-ONCOLOGY

Pharmacokinetics and efficacy of pemetrexed in patients with brain or leptomeningeal metastases

(2013) Priya Kumthekar et al.   JOURNAL OF NEURO-ONCOLOGY

Phase II trial of temozolomide for leptomeningeal metastases in patients with solid tumors

(2012) Pedro Pérez Segura et al.   JOURNAL OF NEURO-ONCOLOGY

Ipilimumab in patients with melanoma and brain metastases: an open-label, phase 2 trial

(2012) Kim Margolin et al.   LANCET ONCOLOGY

Trafficking of immune cells in the central nervous system

(2010) Emma H. Wilson et al.   JOURNAL OF CLINICAL INVESTIGATION