Article
Multidisciplinary Sciences
Mariana Gomez-Schlavon, Hana El-Samad
Summary: Feedback control is a crucial element in life, regulating biological processes from cells to ecosystems. Understanding and designing feedback control systems with biological molecules requires evaluating the contribution and limitations of feedback control mechanisms in cells. A general framework called CoRa (Control Ratio) is introduced here, which quantifies the contribution of biological feedback control mechanisms to adaptation by comparing them to systems without feedback. CoRa provides a simple and intuitive metric applicable to various biological feedback systems.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Neurosciences
David McAlpine, Livia de Hoz
Summary: Analyzing complex auditory scenes relies on learning the statistical structure of sounds in those scenes. The listening brain achieves this by analyzing the statistical structure of acoustic environments and distinguishing between background and foreground sounds. The interplay between feedforward and feedback pathways, known as listening loops, plays a critical role in the auditory brain's ability to adapt to different time scales and tailor neural responses to sound environments. Understanding the role of listening loops at different scales of investigation and their impact on background detection can reveal the fundamental processes that transform hearing into the essential task of listening.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Multidisciplinary Sciences
Jan Rombouts, Sarah Verplaetse, Lendert Gelens
Summary: This study compares the effects of feedback on the periodic rise and fall of protein concentrations or activities through mathematical models. It finds that different mechanisms impose different constraints on the production and degradation rates of proteins, leading to biochemical oscillations.
JOURNAL OF THE ROYAL SOCIETY INTERFACE
(2023)
Article
Mathematics, Applied
Jone Apraiz, Jon Asier Barcena-Petisco
Summary: Network theory is applied to study complex systems in various fields, including physical sciences, engineering, economics, and sociology. This paper focuses on the observability of parabolic equations on networks with loops and presents a novel approach using Carleman inequality. The authors overcome the challenge of circular fallacy caused by the presence of loops through the careful treatment of boundary terms on the junctions. Furthermore, the observability is utilized to prove the null controllability of the network and establish Lipschitz stability for an inverse problem in the parabolic equation.
JOURNAL OF EVOLUTION EQUATIONS
(2023)
Article
Mathematics, Interdisciplinary Applications
Pankaj Gulati, Sudipa Chauhan, Anuj Mubayi, Teekam Singh, Payal Rana
Summary: The study focuses on the prevention of crops from pests, particularly Eggplant fruit and shoot borer, through mathematical modeling and biological control strategies. It discusses dynamic analysis, stability analysis, global stability analysis, and optimization strategies. By exploring a Spatio-temporal model, the study investigates the diffusive pattern in controlling pest populations, and validates theoretical results through numerical simulations.
CHAOS SOLITONS & FRACTALS
(2021)
Article
Biology
Olivier Codol, Mehrdad Kashefi, Christopher J. Forgaard, Joseph M. Galea, J. Andrew Pruszynski, Paul L. Gribble
Summary: Although it is known that motivation can improve motor performance, the mechanisms behind this improvement are unclear. This study systematically tested the effects of reward on different feedback loops in humans and found that only the fastest loops were insensitive to reward. The earliest reward-driven changes were an increase in feedback gains rather than a reduction in response latency. These findings have potential implications for athletic coaching, suggesting that reward-sensitive feedback responses should be specifically targeted for improvement.
Article
Environmental Sciences
Matthew Hamilton, Jonathan Salerno, Alexandra Paige Fischer
Summary: The study evaluates the significance and function of feedback loops embedded within cognitive maps among stakeholders in a fire-prone region in the U.S. West. The findings indicate that cognition of feedback loops is limited among individuals but becomes prominent within groups, highlighting the importance of collaborative decision-making and identifying areas of cognitive biases.
GLOBAL ENVIRONMENTAL CHANGE-HUMAN AND POLICY DIMENSIONS
(2022)
Article
Education & Educational Research
Jiming Zhou, Phillip Dawson, Joanna Hong-Meng Tai, Margaret Bearman
Summary: Respect plays a crucial role in maintaining feedback interactions and sustaining student engagement with feedback, being a key aspect of student feedback literacy. Evaluative, directive and care respect are three essential kinds of respect in the feedback process.
ASSESSMENT & EVALUATION IN HIGHER EDUCATION
(2021)
Article
Biology
Sergio Oscar Verduzco-Flores, Erik De Schutter
Summary: In this paper, the importance of feedback control in understanding neural dynamics of sensorimotor control is demonstrated using a minimal model. The model shows the ability to learn and perform reaching movements, and exhibits emergent properties such as directional tuning and oscillatory dynamics.
Article
Psychology, Social
Steven L. Grover
Summary: This paper explores the impact of respect on performance and work effort based on individual differences in self-esteem. It finds that implicit self-esteem moderates recognition respect, whereas explicit self-esteem moderates appraisal respect. The integration of self-esteem and respect theory helps explain how respectful treatment affects performance.
PERSONALITY AND INDIVIDUAL DIFFERENCES
(2021)
Review
Environmental Sciences
Yi Li, Jiahui Shang, Chi Zhang, Wenlong Zhang, Lihua Niu, Longfei Wang, Huanjun Zhang
Summary: Greenhouse gases (GHGs) from freshwater bodies are influenced by the eutrophic status, with both direct and indirect factors playing a role. The review emphasizes the existence of feedback loops between freshwater eutrophication and GHG emissions. Future research directions and mitigation measures are also discussed to provide insights into controlling GHG emissions.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Genetics & Heredity
Pia Mach, Pavel I. I. Kos, Yinxiu Zhan, Julie Cramard, Simon Gaudin, Jana Tunnermann, Edoardo Marchi, Jan Eglinger, Jessica Zuin, Mariya Kryzhanovska, Sebastien Smallwood, Laurent Gelman, Gregory Roth, Elphege P. Nora, Guido Tiana, Luca Giorgetti
Summary: In mammals, interactions between sequences within topologically associating domains occur frequently and transiently, and become more frequent and longer in the presence of convergent CTCF sites. These interactions stabilize highly dynamic chromosome structures and suppress variability in chromosome folding, suggesting that long-range transcriptional regulation relies on transient physical proximity.
Article
Mathematical & Computational Biology
Lingli Zhou, Fengqing Fu, Yao Wang, Ling Yang
Summary: This paper utilizes a qualitative mathematical model to study the dynamics of immune responses. The simulation results demonstrate the processes of pathological immune responses and explain how the interaction of feedback loops leads to different types of immune responses. The stability analyses reveal the mechanism of rapid immune system activation and the importance of a balance between positive and negative regulation loops in preventing pathological responses. The study also explores how treatment can restore the immune system from a pathological state to a healthy state. Ultimately, this paper provides a better understanding of the dynamics of different immune response processes.
MATHEMATICAL BIOSCIENCES AND ENGINEERING
(2022)
Review
Oncology
Weigang Gu, HongZhang Shen, Lu Xie, Xiaofeng Zhang, Jianfeng Yang
Summary: Pancreatic cancer is a leading cause of global cancer-related deaths, with limited treatment options and low long-term survival rates. Research shows that feedback loops play an important role in the development and treatment of pancreatic cancer, helping to develop targeted treatment strategies.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
David Sanchez-Marin, Samuel Trujano-Camacho, Carlos Perez-Plasencia, David Cantu De Leon, Alma D. Campos-Parra
Summary: This review summarizes the feedback loops regulated by lncRNAs to promote drug resistance and proposes strategies to identify and understand these feedback loops. This knowledge is crucial for optimizing the therapeutic use of oncological drugs.
