Modeling a cataract disorder in mice with prime editing

DNA Prime Editing: A New CRISPR-Based Method to Correct Most Disease-Causing Mutations

(2020) Tracy Hampton   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Base editing-mediated splicing correction therapy for spinal muscular atrophy

(2020) Xiang Lin et al.   CELL RESEARCH

Plant Prime Editors Enable Precise Gene Editing in Rice Cells

(2020) Xu Tang et al.   Molecular Plant

Efficient generation of mouse models with the prime editing system

(2020) Yao Liu et al.   Cell Discovery

Prime Editing: Genome Editing for Rare Genetic Diseases Without Double-Strand Breaks or Donor DNA

(2020) Ianis G. Matsoukas   Frontiers in Genetics

Prime editing for functional repair in patient-derived disease models

(2020) Imre F. Schene et al.   Nature Communications

Efficient base editing in G/C-rich regions to model androgen insensitivity syndrome

(2019) Jianan Li et al.   CELL RESEARCH

Base-Editing-Mediated R17H Substitution in Histone H3 Reveals Methylation-Dependent Regulation of Yap Signaling and Early Mouse Embryo Development

(2019) Guang Yang et al.   Cell Reports

CRISPR/Cas9 technology as a potent molecular tool for gene therapy

(2019) Ansar Karimian et al.   JOURNAL OF CELLULAR PHYSIOLOGY

CRISPR/Cas-Mediated Base Editing: Technical Considerations and Practical Applications

(2019) Kutubuddin A. Molla et al.   TRENDS IN BIOTECHNOLOGY

Allele-specific genome editing of imprinting genes by preferentially targeting non-methylated loci using Staphylococcus aureus Cas9 (SaCas9)

(2019) Yajing Liu et al.   Science Bulletin

Search-and-replace genome editing without double-strand breaks or donor DNA

(2019) Andrew V. Anzalone et al.   NATURE

Treatment of a metabolic liver disease by in vivo genome base editing in adult mice

(2018) Lukas Villiger et al.   NATURE MEDICINE

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

(2017) Nicole M. Gaudelli et al.   NATURE

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

(2016) Alexis C. Komor et al.   NATURE

Correction of a Genetic Disease in Mouse via Use of CRISPR-Cas9

(2013) Yuxuan Wu et al.   Cell Stem Cell

From the periphery to centre stage: de novo single nucleotide variants play a key role in human genetic disease

(2013) Chee-Seng Ku et al.   JOURNAL OF MEDICAL GENETICS

A 1-bp deletion in the γC-crystallin leads to dominant cataracts in mice

(2010) Liya Zhao et al.   MAMMALIAN GENOME

Single-nucleotide evolutionary constraint scores highlight disease-causing mutations

(2010) Gregory M Cooper et al.   NATURE METHODS

Single-nucleotide mutation rate increases close to insertions/deletions in eukaryotes

(2008) Dacheng Tian et al.   NATURE