Whole-Mount Kidney Clearing and Visualization Reveal Renal Sympathetic Hyperinnervation in Heart Failure Mice

Function of Renal Nerves in Kidney Physiology and Pathophysiology

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Renal Sympathetic Nerve-Derived Signaling in Acute and Chronic Kidney Diseases

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Tissue clearing and its applications in neuroscience

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Afferent innervation of the ischemic kidney contributes to renal dysfunction in renovascular hypertensive rats

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Cardiorenal syndrome: Multi‐organ dysfunction involving the heart, kidney and vasculature

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Device-based therapies for arterial hypertension

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Versatile whole-organ/body staining and imaging based on electrolyte-gel properties of biological tissues

(2020) Etsuo A. Susaki et al.   Nature Communications

Sympathetic nerve traffic overactivity in chronic kidney disease

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Cardiorenal Syndrome: Classification, Pathophysiology, Diagnosis, and Treatment Strategies: A Scientific Statement From the American Heart Association

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Comprehensive three-dimensional analysis (CUBIC-kidney) visualizes abnormal renal sympathetic nerves after ischemia/reperfusion injury

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Selective afferent renal denervation mitigates renal and splanchnic sympathetic nerve overactivity and renal function in chronic kidney disease-induced hypertension

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Advanced CUBIC tissue clearing for whole-organ cell profiling

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Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals

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Quantification of sympathetic hyperinnervation and denervation after myocardial infarction by three-dimensional assessment of the cardiac sympathetic network in cleared transparent murine hearts

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Minimally Invasive Transverse Aortic Constriction in Mice

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Chemical Principles in Tissue Clearing and Staining Protocols for Whole-Body Cell Profiling

(2016) Kazuki Tainaka et al.   Annual Review of Cell and Developmental Biology

Shrinkage-mediated imaging of entire organs and organisms using uDISCO

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Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging

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Fast immuno-labeling by electrophoretically driven infiltration for intact tissue imaging

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The renal nerves in chronic heart failure: efferent and afferent mechanisms

(2015) Alicia M. Schiller et al.   Frontiers in Physiology

Whole-Brain Imaging with Single-Cell Resolution Using Chemical Cocktails and Computational Analysis

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Whole-Body Imaging with Single-Cell Resolution by Tissue Decolorization

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Structural and molecular interrogation of intact biological systems

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Three-dimensional imaging of solvent-cleared organs using 3DISCO

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Cardiorenal syndrome: pathophysiology and potential targets for clinical management

(2012) Parta Hatamizadeh et al.   Nature Reviews Nephrology

Effects of Beta-Adrenergic Antagonists in Patients With Chronic Kidney Disease

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Three-dimensional imaging of the unsectioned adult spinal cord to assess axon regeneration and glial responses after injury

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Improved survival with bisoprolol in patients with heart failure and renal impairment: an analysis of the cardiac insufficiency bisoprolol study II (CIBIS-II) trial

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The Influence of Renal Function on Clinical Outcome and Response to β-Blockade in Systolic Heart Failure: Insights From Metoprolol CR/XL Randomized Intervention Trial in Chronic HF (MERIT-HF)

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