期刊
CATALYSTS
卷 11, 期 7, 页码 -出版社
MDPI
DOI: 10.3390/catal11070780
关键词
Mentha arvensis; green synthesis; magnesium oxide; antibacterial; bio-compatible; anti-cancer
In this study, Mentha arvensis mediated Magnesium oxide nanoparticles were successfully synthesized and characterized by various techniques. The nanoparticles showed significant antimicrobial, anticancer, antioxidant and anti-inflammatory activities, indicating their potential as a promising biomedical material.
In the present study Mentha arvensis medaited Magnesium oxide nanoparticles were synthesized by novel green route followed by advanced characterization via XRD, FTIR, UV, SEM, TEM, DLS and TGA. The mean grain size of 32.4 nm and crystallite fcc morphology were confirmed by X-ray diffractive analysis. Scanning and Transmission electron microscopy analysis revealed the spherical and elliptical morphologies of the biosynthesized nanoparticles. Particle surface charge of -16.1 mV were determined by zeta potential and zeta size of 30-120 nm via dynamic light scattering method. Fourier transform spectroscopic analysis revealed the possible involvement of functional groups in the plant extract in reduction of Mg2+ ions to Mg-0. Furthermore, the antioxidant, anti-Alzheimer, anti-cancer, and anti-H. pylori activities were performed. The results revealed that MgO-NPs has significant anti-H. pyloric potential by giving ZOI of 17.19 +/- 0.83 mm against Helicobacter felis followed by Helicobacter suis. MgO-NPs inhibited protein kinase enzyme up to 12.44 +/- 0.72% at 5 mg/mL and thus showed eminent anticancer activity. Significant free radicals scavenging and hemocompatability was also shown by MgO-NPs. MgO-NPs also displayed good inhibition potential against Hela cell lines with maximum inhibition of 49.49 +/- 1.18 at 400 mu g/mL. Owing to ecofriendly synthesis, non-toxic and biocompatible nature, Mentha arvensis synthesized MgO-NPs can be used as potent antimicrobial agent in therapeutic applications.
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