Exocrine pancreas proteases regulate β-cell proliferation in zebrafish ciliopathy models and in murine systems

Genomic knockout of alms1 in zebrafish recapitulates Alström syndrome and provides insight into metabolic phenotypes

(2019) Jessica E Nesmith et al.   HUMAN MOLECULAR GENETICS

Pancreatic β Cell Regeneration as a Possible Therapy for Diabetes

(2018) Cristina Aguayo-Mazzucato et al.   Cell Metabolism

Silk fibroin preserves beta cell function under inflammatory stress while stimulating islet cell surface GLUT2 expression

(2018) N. Ashari et al.   CELLULAR IMMUNOLOGY

Glucose homeostasis dependency on acini–islet–acinar (AIA) axis communication: a new possible pathophysiological hypothesis regarding diabetes mellitus

(2018) Stefan G. Pierzynowski et al.   Nutrition & Diabetes

Relationship between circulating levels of pancreatic proteolytic enzymes and pancreatic hormones

(2017) Sakina H. Bharmal et al.   PANCREATOLOGY

Whole organism transcriptome analysis of zebrafish models of Bardet-Biedl Syndrome and Alström Syndrome provides mechanistic insight into shared and divergent phenotypes

(2016) Timothy L. Hostelley et al.   BMC GENOMICS

SerpinB1 Promotes Pancreatic β Cell Proliferation

(2016) Abdelfattah El Ouaamari et al.   Cell Metabolism

Isolation and Characterization of Single Cells from Zebrafish Embryos

(2016) Leigh Ann Samsa et al.   Jove-Journal of Visualized Experiments

Fate mapping ofptf1a-expressing cells during pancreatic organogenesis and regeneration in zebrafish

(2015) Yue J. Wang et al.   DEVELOPMENTAL DYNAMICS

Decreased insulin secretion and glucose clearance in exocrine pancreas-insufficient pigs

(2015) Liudmyla Lozinska et al.   EXPERIMENTAL PHYSIOLOGY

High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9

(2015) Gaurav K. Varshney et al.   GENOME RESEARCH

Differential effects on β-cell mass by disruption of Bardet–Biedl syndrome or Alstrom syndrome genes

(2015) Sukanya Lodh et al.   HUMAN MOLECULAR GENETICS

Antibody Response to Serpin B13 Induces Adaptive Changes in Mouse Pancreatic Islets and Slows Down the Decline in the Residual Beta Cell Function in Children with Recent Onset of Type 1 Diabetes Mellitus

(2015) Yury Kryvalap et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exocrine Pancreatic Insufficiency in Diabetic Patients: Prevalence, Mechanisms, and Treatment

(2015) Matteo Piciucchi et al.   International Journal of Endocrinology

Primary cilia in pancreatic development and disease

(2014) Sukanya Lodh et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

IFT27, encoding a small GTPase component of IFT particles, is mutated in a consanguineous family with Bardet-Biedl syndrome

(2014) M. A. Aldahmesh et al.   HUMAN MOLECULAR GENETICS

Basal body proteins regulate Notch signaling through endosomal trafficking

(2014) C. C. Leitch et al.   JOURNAL OF CELL SCIENCE

The CTRB1/2 Locus Affects Diabetes Susceptibility and Treatment via the Incretin Pathway

(2013) Leen M. ‘t Hart et al.   DIABETES

Nutrient Excess Stimulates  -Cell Neogenesis in Zebrafish

(2012) L. A. Maddison et al.   DIABETES

Bardet–Biedl syndrome

(2012) Elizabeth Forsythe et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

Endothelial Nrf2 activation: a new target for resveratrol?

(2010) György Haskó et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Alström syndrome: insights into the pathogenesis of metabolic disorders

(2010) Dorothée Girard et al.   Nature Reviews Endocrinology

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

(2009) Jeffrey C Barrett et al.   NATURE GENETICS