Article
Biochemistry & Molecular Biology
Xiaodi Niu, Li Lin, Lu Liu, Hongsu Wang
Summary: A new glucose oxidase-N-succinyl chitosan (GOD-NSCS) nanospheres was developed for suppressing anthracnose in postharvest mangoes. The GOD-NSCS nanospheres showed excellent anti-Colletotrichum gloeosporioides activity and prolonged the preservation period of mangoes. Computational biology analysis revealed that GOD-NSCS nanospheres had similar oxidation efficiency with more H2O2 production compared to free GOD.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Xiaozhen Yang, Aoya Shi, Yameng Song, Chao Niu, Xiaowen Yu, Xingliang Shi, Yangyang Pang, Xueli Ma, Yongxu Cheng
Summary: The study found that melatonin has a protective effect on Chinese mitten crab under ammonia nitrogen stress, improving antibacterial and antioxidant capacity, and alleviating the damage to digestive and immune functions caused by ammonia nitrogen.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Avimanu Sharma, Sanjeev Kumar, Ritu Singh
Summary: The study proposed a new formulation of coated nanourea for slow and sustainable nitrogen release. The synthesized nanourea showed reduced nitrate leaching and improved plant growth compared to commercial urea. The nanourea/chitosan nanocomposite exhibited potential as an alternative to commercial urea for sustainable agriculture.
ENVIRONMENTAL SCIENCE-NANO
(2022)
Article
Biochemistry & Molecular Biology
Wenbo Li, Yujia Zhao, Wuliang Sun, Tungalag Dong, Marleny D. A. Saldana, Wenxiu Sun
Summary: In this study, a nanocomposite hydrogel with pH, temperature, and salt ion responsiveness was successfully synthesized using free radical polymerization. Thymol was embedded in the hydrogel and the nanoparticles could be adsorbed on a chitosan film. The loaded thymol nanoparticles exhibited longer release time and stronger antibacterial activity, indicating their potential applications in food packaging.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Polymer Science
Weijie Yuan, Sihan Li, Haohui Guan, Shuai Zhang, Yaoxiang Zhang, Min Zhang, Yi Yu, Xiangyi Chen
Summary: A novel and biodegradable composite hydrogel was prepared using gelatin, chitosan, and polylactic acid as raw materials to improve nitrogen utilization efficiency and reduce environmental pollution from nitrogen losses. Urea loading and swelling behavior of the hydrogel were investigated, along with release behavior in aqueous phase. Results showed controllable urea loading in different concentrations and a three-stage sustained release behavior in water, fitting the Ritger-Peppas model. The hydrogel exhibited good water absorption and retention properties, with high potential for use in sustainable agriculture and forestry, particularly in arid and degraded land.
Article
Energy & Fuels
Shaon Kumar Das, Goutam Kumar Ghosh
Summary: The study demonstrated the significance of biochar in slow-release fertilizers, showing its ability to increase crop yield, improve soil quality, and reduce nutrient leaching. Different types of biochar exhibited varying levels of nutrient retention and release efficiency, with pine needle biochar being the most effective.
BIOMASS CONVERSION AND BIOREFINERY
(2021)
Article
Agriculture, Dairy & Animal Science
Stuart F. Kirwan, Karina M. Pierce, Eleonora Serra, Michael McDonald, Gaurav Rajauria, Tommy M. Boland
Summary: The study found that adding chitosan and different levels of crude protein to beef cattle feed can affect nutrient intake, digestion, and nitrogen excretion. Chitosan can reduce nutrient digestibility, while high crude protein diets increase nitrogen excretion. High crude protein diets lead to increased nitrogen excretion in urine, while chitosan inclusion increases nitrogen excretion in feces.
Article
Biochemical Research Methods
Hamed Sahebi, Hamed Zandavar, Seied Mahdi Pourmortazavi, Somayeh Mirsadeghi
Summary: A novel magnetic nanocomposite of chitosan-grafted-poly(N-vinylcaprolactam) (Fe3O4/SiO2/CHT-g-PNVCL MNC) was synthesized and applied for the simultaneous extraction of trans-resveratrol and its major phase II metabolites from rat plasma. Various techniques were used to characterize the physicochemical properties of the synthesized nanomaterials, meeting FDA requirements for biological analysis methods.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2021)
Article
Electrochemistry
Chao Liu, Zekun Wang, Guangyu Xu
Summary: The modified electrode (ss g-GOx/MnO2 NPs/MB-CS/GCE) was successfully developed for electrochemical detection of ss-glucan in morel samples. The combination of MB-CS and MnO2 NPs enhanced the sensitivity and selectivity of the biosensor. The linear range, sensitivity, and detection limit were determined to be 0-10,400 ng/mL, 0.00441 mu A/ng.mL(-1), and 0.34 ng/mL, respectively. The applicability of the biosensor in morel samples was confirmed through significant conformity between the amperometric and ss-Glucan Assay Kit assays.
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
(2023)
Article
Materials Science, Biomaterials
Faten Ismail Abou El Fadl, Yasser H. Gad
Summary: This study aimed to manufacture a new pH-responsive hydrogel based on DMAEMA and CS by the impact of gamma radiation, which can be used as a controlled drug delivery system and smart drug carrier for stomach treatment. The hydrogels show high sensitivity and magnetic properties, with increased surface area and reactivity, making them valuable for drug delivery applications.
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
(2022)
Article
Agriculture, Multidisciplinary
M. Latha, K. S. Subramanian, D. Jeya Sundara Sharmila, K. Raja, S. K. Rajkishore, T. Chitdeshwari
Summary: Urea is a widely used fertilizer, but its usage efficiency is low and causes environmental pollution. This research focuses on encapsulating urea molecules using a lignin-chitosan composite, which can effectively trap nitrogenous fertilizer. Nanocomposites were developed using lignin nanoparticles obtained from coconut coir and chitosan. The nanocomposites were characterized using various techniques. The developed nanofertilizer has a slow release of total nitrogen for up to 15 days in the soil, contributing to improved nitrogen use efficiency.
ACS AGRICULTURAL SCIENCE & TECHNOLOGY
(2023)
Article
Materials Science, Characterization & Testing
Faten I. Abou El Fadl, Ashraf M. Abdel Ghaffar, Naeem M. El-Sawy
Summary: A highly swellable and biocompatible hydrogel, prepared by gamma radiation, was used as a precursor for the synthesis of ZnO nanocomposite. Detailed characterization of the hydrogel using various techniques confirmed its physical and chemical properties. The resulting nanocomposite hydrogel showed great potential for biomedical applications.
POLYMERS & POLYMER COMPOSITES
(2022)
Article
Agronomy
Oscar Ivan Guillen-Castillo, Angel Natanael Rojas-Velazquez, Jorge Alonso Alcala-Jauregui, Catarina Loredo-Osti, Hugo Magdaleno Ramirez-Tobias, Vincenzo Bertolini, Juan Carlos Rodriguez Ortiz
Summary: This study evaluated the application of nitrogenous nanocomposites (NCN) as a slow-release fertilizer (SRF) in soil and its impact on the growth of lettuce crops. The results showed that most NCN treatments were comparable to the control group after 40 days, although the 25/0 treatment resulted in a 20% decrease in fresh weight and an 18% decrease in leaf area. The NCN/FC 0/100, 50/50, and 75/25 ratios increased nitrate concentration in leaves by 19%. NCN gradually released nitrates at higher amounts than calculated.
TERRA LATINOAMERICANA
(2023)
Article
Materials Science, Multidisciplinary
R. B. Salikhov, R. A. Zilberg, E. O. Bulysheva, A. D. Ostaltsova, T. R. Salikhov, Yu. B. Teres
Summary: The article discusses the study of nanocomposite thin films based on a polyelectrolyte complex of chitosan and chitosan succinamide. Single-walled carbon nanotubes are used as fillers. It was found that the nanocomposite films have a larger effective surface area and electron transfer rate compared to the polyelectrolyte complex films, making them suitable for electroanalysis. Scanning electron microscopy revealed the presence of carbon nanotube filaments in the nanocomposite structure. Sensory sensitivity to air humidity and ammonia vapors was observed in the resistive thin-film nanocomposite structures. Dependencies of flowing current on relative humidity and ammonia vapor concentration were measured using these nanocomposite materials.
LETTERS ON MATERIALS
(2023)
Article
Agronomy
Dechen Angmo, Sat Pal Sharma, Anu Kalia, Navjot Singh Brar, Vinay Bhardwaj
Summary: This study aimed to investigate the morpho-physiological responses of different potato genotypes to cold stress. The results showed that frost-tolerant genotypes experienced less damage and recovered faster after freezing treatment compared to susceptible genotypes. However, cold acclimation did not enhance freezing tolerance in potatoes.
Article
Toxicology
Meng Liu, Ling Zhao, Jin-Tao Wei, Yu-Xuan Huang, Mahmoud Mohamed Khalil, Wen-Da Wu, Kamil Kuca, Lv-Hui Sun
Summary: This study explored the mechanism of T-2 toxin-induced small intestine injury in broilers by integrating advanced microbiomic, metabolomic, and transcriptomic technologies. The results showed that T-2 toxin exposure at different doses reduced feed intake, body weight gain, and induced histopathological lesions in the small intestine. T-2 toxin also affected antioxidant enzyme activities, oxidative stress markers, and was associated with nucleotide and glycerophospholipid metabolism, inflammation, and apoptosis. In conclusion, this study provides novel insights into the toxic mechanisms of T-2 toxin in the small intestine of broilers and suggests potential detoxification strategies.
ARCHIVES OF TOXICOLOGY
(2023)
Review
Toxicology
Li You, Eugenie Nepovimova, Marian Valko, Qinghua Wu, Kamil Kuca
Summary: Mycotoxins induce oxidative stress, hypoxia, and cellular senescence, which are involved in immunosuppressive effects. Activation of senescence markers and cell cycle arrest pathways by mycotoxins further contribute to immunomodulatory effects.
ARCHIVES OF TOXICOLOGY
(2023)
Review
Computer Science, Information Systems
Siti Dianah Abdul Bujang, Ali Selamat, Ondrej Krejcar, Farhan Mohamed, Lim Kok Cheng, Po Chan Chiu, Hamido Fujita
Summary: This study aims to review existing research and provide a state-of-the-art approach for handling imbalanced classification in higher education, focusing on student grade prediction. The survey results reveal that the widely applied method for addressing imbalanced problems in student grade prediction is the data-level approach using SMOTE oversampling. However, there is a lack of application of hybrid and feature selection methods to improve the generalization of predictive models. The outcomes of this review will guide professionals and academic researchers in dealing with imbalanced classification, especially in higher education.
Article
Plant Sciences
Ying-Ning Zou, Qiu-Yun Qin, Wen-Ya Ma, Li-Jun Zhou, Qiang-Sheng Wu, Yong-Jie Xu, Kamil Kuca, Abeer Hashem, Al-Bandari Fahad Al-Arjani, Khalid F. Almutairi, Elsayed Fathi Abd-Allah
Summary: Metabolomic analysis revealed the metabolic mechanisms of mycorrhiza-enhanced drought tolerance in walnuts. The results showed that AMF inoculation increased biomass production and leaf water potential in walnut under drought stress, accompanied by regulation of numerous metabolic pathways. Furthermore, the regulation of walnut metabolites by AMF exhibited differences under different stress conditions.
Article
Biochemistry & Molecular Biology
Tushuai Li, Yue Gu, Baocai Xu, Kamil Kuca, Jie Zhang, Wenda Wu
Summary: CircZBTB44 is upregulated in renal cell carcinoma tissues and its knockdown inhibits RCC cell viability, proliferation, migration, and tumorigenesis. HNRNPC mediates circZBTB44 interaction with IGF2BP3, resulting in upregulation of HK3 and promotion of RCC cell malignant behaviors. This study provides new insights into targeted therapy for RCC.
Article
Environmental Sciences
Jiefeng Li, Ying Deng, Yating Wang, Eugenie Nepovimova, Qinghua Wu, Kamil Kuca
Summary: Mycotoxins can cause immune dysfunction and diseases in animals and humans. The mechanisms by which mycotoxins induce immunotoxicity involve cellular senescence, activation of signaling pathways, and secretion of senescence-associated secretory phenotype (SASP) cytokines. Cellular senescence is triggered by DNA damage, which also leads to cell cycle arrest and chronic inflammation, eventually leading to immune exhaustion.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2023)
Article
Computer Science, Artificial Intelligence
Xiang Li, Zeshui Xu, Hai Wang, Ondrej Krejcar, Kamil Kuca, Enrique Herrera-Viedma
Summary: In this paper, a novel multi-criteria three-way decision (TWD) method is proposed to solve classification and sorting problems by incorporating both qualitative and quantitative information. Traditional TWD theories often neglect the requirements and targets of decision-makers, thus a parameter is designed to reflect the preference degree of the decision-maker's requirements. Using a combination of real numbers and interval numbers for quantitative information and interval-valued double hierarchy linguistic term sets for qualitative information, the proposed method demonstrates its effectiveness in a case study on the selection of algorithm engineers in recruitment process, outperforming other methods.
EXPERT SYSTEMS WITH APPLICATIONS
(2023)
Article
Food Science & Technology
Luying Zhang, Xu Wang, Eugenie Nepovimova, Qinghua Wu, Wenda Wu, Kamil Kuca
Summary: Trichothecene mycotoxin deoxynivalenol (DON) negatively regulates immune response by damaging host immune system and harming the organism's health. We hypothesized that DON can initiate an active immunosuppressive mechanism similar to immune evasion to alter the cellular microenvironment and evade immune surveillance.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Article
Food Science & Technology
Yi-Xin Mo, Meng-Ling Ruan, Jie Wang, Ying Liu, Yuan-Yuan Wu, Guan-Lin Wang, Yan-Ming Han, Hai-Feng Wan, Dessalegn Lamesgen, Kamil Kuca, Jiang Deng, Lv-Hui Sun
Summary: This study evaluated the efficacy of TOXO-XL, an integrated mycotoxin-mitigating agent, in mitigating aflatoxin B1 (AFB1)-induced damage in three cell lines: Leghorn male hepatoma (LMH), porcine jejunum epithelial cell line (IPEC-J2), and porcine alveolar macrophages (3D4/21). The results showed that XL supplementation could ameliorate the cytotoxic effects of AFB1, including cell viability, ROS, apoptosis, DNA damage, migration, and phagocytosis abilities. XL also attenuated AFB1-induced inflammatory response and reversed the alterations in apoptotic signaling. Additionally, XL may have a protective effect on the intestinal barrier by restoring occludin protein.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Article
Pharmacology & Pharmacy
Haoyu Gao, Eugenie Nepovimova, Zbynek Heger, Marian Valko, Qinghua Wu, Kamil Kuca, Vojtech Adam
Summary: Senescent cells secrete harmful molecules that damage surrounding cells, leading to age-related diseases. Hypoxia has been found to play a critical role in cellular senescence by regulating the levels of senescence markers. In addition, gut microbiota and exosomal RNAs are involved in cellular senescence. This review provides new insights into hypoxia-mediated cellular senescence and potential strategies for anti-aging and disease treatment.
PHARMACOLOGICAL RESEARCH
(2023)
Article
Engineering, Electrical & Electronic
Mohan Karnati, Ayan Seal, Debotosh Bhattacharjee, Anis Yazidi, Ondrej Krejcar
Summary: Emotion recognition is important in cognitive psychology research, but measuring emotions is challenging. Facial expression recognition (FER) approaches have been designed, but challenges increase when data transitions to real-world circumstances. Deep learning (DL) techniques have greatly improved FER systems, but problems such as overfitting and complications unrelated to expressions still exist. This study provides a comprehensive survey of DL-based FER methods, discussing different components and analyzing their performance, advantages, and limitations. It also explores relevant databases and discusses the current status and future directions of facial emotion recognition.
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
(2023)
Article
Mathematical & Computational Biology
Sridevi Sriram, Hayder Natiq, Karthikeyan Rajagopal, Ondrej Krejcar, Hamidreza Namazi
Summary: Investigating the effect of changes in neuronal connectivity on the brain's behavior is a crucial topic in neuroscience. Complex network theory provides a powerful tool to study these changes. This paper focuses on the effect of asymmetry coupling changes on the behaviors of a multi-layer neuronal network.
MATHEMATICAL BIOSCIENCES AND ENGINEERING
(2023)
Article
Computer Science, Artificial Intelligence
Ayca Kirimtat, M. Fatih Tasgetiren, Ondrej Krejcar, Ozge Buyukdagli, Petra Maresova
Summary: This article introduces the concepts of smart cities and floating cities, as well as the use of evolutionary algorithms to solve the complex design challenges. The study proposes two multi-objective algorithms and compares them with a traditional algorithm, demonstrating the advantages of the proposed algorithms in generating Pareto ranking results.
EXPERT SYSTEMS WITH APPLICATIONS
(2024)
Article
Biology
Chahak Jain, Shilpa Gupta, Sat Pal Sharma, Manjeet Kaur Sangha, Anu Kalia, Navraj Kaur Sarao
Summary: This study investigated the proteinaceous alterations in five different genotypes of Cucumis melo in response to Fusarium oxysporum f. sp. melonis (FOM) infestation. The results showed significant differences in protein content and pathogenesis related (PR) protein activities among resistant, moderate, and susceptible genotypes, with the highest levels observed at 14 days after inoculation in the resistant genotypes. Gene expression analysis also supported these findings. Additionally, the absence of a specific protein band in the resistant genotype suggests a potential resistance pathway. Further exploration of this PR protein could aid in the development of FOM-resistant C. melo varieties.
