标题
De novo mutational signature discovery in tumor genomes using SparseSignatures
作者
关键词
Point mutation, Cancers and neoplasms, Pancreatic cancer, Simulation and modeling, Cosine similarity, Cancer genomics, Breast cancer, DNA methylation
出版物
PLoS Computational Biology
Volume 17, Issue 6, Pages e1009119
出版商
Public Library of Science (PLoS)
发表日期
2021-06-29
DOI
10.1371/journal.pcbi.1009119
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The repertoire of mutational signatures in human cancer
- (2020) Ludmil B. Alexandrov et al. NATURE
- The mutational signature profile of known and suspected human carcinogens in mice
- (2020) Laura Riva et al. NATURE GENETICS
- Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis
- (2019) Mia Petljak et al. CELL
- APOBEC3B and APOBEC mutational signature as potential predictive markers for immunotherapy response in non-small cell lung cancer
- (2018) Shixiang Wang et al. ONCOGENE
- SIMLR: A Tool for Large-Scale Genomic Analyses by Multi-Kernel Learning
- (2018) Bo Wang et al. PROTEOMICS
- Somatic mutant clones colonize the human esophagus with age
- (2018) Iñigo Martincorena et al. SCIENCE
- Multi-omic tumor data reveal diversity of molecular mechanisms that correlate with survival
- (2018) Daniele Ramazzotti et al. Nature Communications
- Visualization and analysis of single-cell RNA-seq data by kernel-based similarity learning
- (2017) Bo Wang et al. NATURE METHODS
- Exploring background mutational processes to decipher cancer genetic heterogeneity
- (2017) Alexander Goncearenco et al. NUCLEIC ACIDS RESEARCH
- signeR: an empirical Bayesian approach to mutational signature discovery
- (2016) Rafael A. Rosales et al. BIOINFORMATICS
- Landscape of somatic mutations in 560 breast cancer whole-genome sequences
- (2016) Serena Nik-Zainal et al. NATURE
- Tissue-specific mutation accumulation in human adult stem cells during life
- (2016) Francis Blokzijl et al. NATURE
- Mutational signatures associated with tobacco smoking in human cancer
- (2016) L. B. Alexandrov et al. SCIENCE
- Clock-like mutational processes in human somatic cells
- (2015) Ludmil B Alexandrov et al. NATURE GENETICS
- Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets
- (2015) Kornelius Schulze et al. NATURE GENETICS
- A Simple Model-Based Approach to Inferring and Visualizing Cancer Mutation Signatures
- (2015) Yuichi Shiraishi et al. PLoS Genetics
- Regularization Paths for Generalized Linear Models via Coordinate Descent
- (2015) Jerome Friedman et al. Journal of Statistical Software
- Non-negative Matrix Factorization under equality constraints—a study of industrial source identification
- (2014) A. Limem et al. APPLIED NUMERICAL MATHEMATICS
- Mechanisms underlying mutational signatures in human cancers
- (2014) Thomas Helleday et al. NATURE REVIEWS GENETICS
- Heterogeneity of genomic evolution and mutational profiles in multiple myeloma
- (2014) Niccolo Bolli et al. Nature Communications
- Signatures of mutational processes in human cancer
- (2013) Ludmil B. Alexandrov et al. NATURE
- Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity
- (2013) Austin M Dulak et al. NATURE GENETICS
- Cancer Genome Landscapes
- (2013) B. Vogelstein et al. SCIENCE
- Deciphering Signatures of Mutational Processes Operative in Human Cancer
- (2013) Ludmil B. Alexandrov et al. Cell Reports
- A flexible R package for nonnegative matrix factorization
- (2010) Renaud Gaujoux et al. BMC BIOINFORMATICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now