Article
Obstetrics & Gynecology
Amanda Koire, Leena Mittal, Carmina Erdei, Cindy H. Liu
Summary: This study found that depressive symptoms in pregnant women were negatively associated with quality of maternal-fetal bonding, while higher levels of anxiety were positively associated with bonding. Past history of depression or generalized anxiety did not seem to be as relevant as current symptomatology. Maternal resilience, rather than distress tolerance, appeared to be a protective factor for bonding. Higher levels of worry regarding the impact of COVID-19 on health were significantly associated with improved bonding, while worries about the impact on pregnancy or resources were not significantly associated with bonding.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Psychology, Multidisciplinary
Celia Campos-Garzon, Blanca Riquelme-Gallego, Alejandro de la Torre-luque, Rafael A. Caparros-Gonzalez
Summary: During the COVID-19 pandemic, pregnant women have shown increased levels of anxiety and depression symptoms, primarily attributed to fear of contagion and concerns regarding the health of the fetus.
BEHAVIORAL SCIENCES
(2021)
Article
Medicine, General & Internal
Roseli Nomura, Isabela Tavares, Ana Carla Ubinha, Maria Laura Costa, Maria Lucia Opperman, Marianna Brock, Alberto Trapani, Lia Damasio, Nadia Reis, Vera Borges, Alberto Zaconeta, Ana Cristina Araujo, Rodrigo Ruano
Summary: The COVID-19 pandemic has significantly impacted maternal anxiety, particularly in relation to maternal knowledge and concerns about the pandemic.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Clinical Neurology
Ilana Haliwa, Jenna Wilson, Jerin Lee, Natalie J. Shook
Summary: The study found significant increases in anxiety and stress among U.S. adults from before to during the COVID-19 pandemic. Financial concerns and the impact of the pandemic on daily life emerged as the most consistent predictors of psychological distress across the samples.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Psychiatry
Jasmine Turna, Jasmine Zhang, Nina Lamberti, Beth Patterson, William Simpson, Ana Paula Francisco, Carolina Goldman Bergmann, Michael Van Ameringen
Summary: This study investigated the impact of COVID-19 on mental health and related risk factors. The findings show that in the sample surveyed, 88% of individuals felt anxious about their loved ones getting infected with the virus, with 31% meeting criteria for generalized anxiety disorder and 29% for major depressive disorder. Factors such as gender, age, and past mental health treatment were identified as significant predictors of these mental health issues.
JOURNAL OF PSYCHIATRIC RESEARCH
(2021)
Review
Orthopedics
Lori Jia, Michael V. Carter, Antonio Cusano, Xinning Li, John D. Kelly, Jessica D. Bartley, Robert L. Parisien
Summary: The COVID-19 pandemic has negatively affected the mental and emotional health of athletes globally, with an increased risk of poor mental health outcomes for female athletes and those in higher levels of play. Providing psychological support, access to training facilities, and utilizing healthy coping mechanisms can improve mental health outcomes for athletes.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2023)
Article
Multidisciplinary Sciences
Haleema Saeed, Yuan-Chiao Lu, Nickie Andescavage, Kushal Kapse, Nicole R. Andersen, Catherine Lopez, Jessica Quistorff, Scott Barnett, Diedtra Henderson, Dorothy Bulas, Catherine Limperopoulos
Summary: The COVID-19 pandemic has led to increased prenatal maternal distress, which can adversely affect pregnancy outcomes through placental mediation. This study used advanced MRI to examine the impact of the pandemic and maternal distress on in vivo placental development. Results showed that the pandemic cohort had higher maternal stress and depression scores, as well as altered placental morphometry and texture compared to the pre-pandemic controls. Maternal distress was found to mediate the relationship between pandemic status and placental features. This suggests an underappreciated link between disturbances in the maternal environment and perturbed placental development, with long-term effects on offspring currently being investigated.
SCIENTIFIC REPORTS
(2023)
Article
Obstetrics & Gynecology
Virginia Medina-Jimenez, Maria de la Luz Bermudez-Rojas, Hector Murillo-Bargas, Ana Claudia Rivera-Camarillo, Jairo Munoz-Acosta, Tania Gabriela Ramirez-Abarca, Diana Magdalena Esparza-Valencia, Alejandra Cristina Angeles-Torres, Leticia Lara-Avila, Veronica Aide Hernandez-Munoz, Fernando Javier Madrigal-Tejeda, Gaston Eduardo Estudillo-Jimenez, Luis Mauricio Jacobo-Enciso, Johnatan Torres-Torres, Salvador Espino-y-Sosa, Mariana Baltazar-Martinez, Job Villanueva-Calleja, Aaron Ezequiel Nava-Sanchez, Claudia Elvira Mendoza-Carrera, Cesar Aguilar-Torres, Cuauhtemoc Celis-Gonzalez, Raigam Jafet Martinez-Portilla
Summary: The COVID-19 pandemic has had an impact on the stress and depression levels of pregnant women in Mexico, resulting in high levels of perceived stress and depression.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Kobi V. Ajayi, Elizabeth Wachira, Obasanjo Afolabi Bolarinwa, Beulah D. Suleman
Summary: The COVID-19 pandemic has had a profound impact on global mental health, particularly putting pregnant and postpartum mothers at increased risk of poor psychological well-being. In Africa, with weak health systems, inadequate mental health policies and infrastructure, high poverty rates and unreliable maternal care, the pandemic is expected to have dire consequences on maternal mental health. Multipronged mental health interventions and strategies that consider the heterogeneity within and between African regions are needed to close existing and widening global health disparities and achieve the United Nations Sustainable Development Goals by 2030.
EPIDEMIOLOGY AND HEALTH
(2021)
Article
Nursing
Refika Genc Koyucu, Pelin Palas Karaca
Summary: The study found that pregnant women experienced higher levels of anxiety, depression, and stress during the Covid-19 pandemic. Factors such as unemployment, inadequate social support, obstetric risks, and financial strain were all found to impact the mental health of pregnant women.
Article
Psychology, Multidisciplinary
Cillian P. McDowell, Matthew P. Herring, Jeni Lansing, Cassandra S. Brower, Jacob D. Meyer
Summary: During the COVID-19 pandemic, switching to working from home showed no significant impact on mental health, while job loss was associated with higher levels of depression, anxiety, and stress, and lower positive mental health. Tailored interventions may be needed to mitigate the negative effects of job loss on mental health during times of societal stress.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Neurosciences
Kathryn Y. Manning, Xiangyu Long, Dana Watts, Lianne Tomfohr-Madsen, Gerald F. Giesbrecht, Catherine Lebel
Summary: The study found that the COVID-19 pandemic may have long-term impacts on children and highlighted the important role of social support for pregnant individuals and developing infants. These findings provide timely evidence for informing clinical practice and policy, underscoring the importance of social support.
BIOLOGICAL PSYCHIATRY
(2022)
Article
Psychology, Clinical
Ljiljana Jelicic, Svetlana Jankovic, Mirjana Sovilj, Ivana Bogavac, Andela Drobnjak, Aleksandra Dimitrijevic, Misko Subotic
Summary: This study aims to explore the impact of the COVID-19 pandemic on pregnant women's anxiety and identify its associated factors. The findings reveal that the COVID-19 pandemic affects the mental health of pregnant women, with a nonlinear dependence of state anxiety on observed associated factors and their complex interactions.
PSYCHOLOGY RESEARCH AND BEHAVIOR MANAGEMENT
(2022)
Article
Psychology, Multidisciplinary
Juliana Alvares Duarte Bonini Campos, Lucas Arrais Campos, Bianca Gonzalez Martins, Adriano Palomino de Oliveira, Fabiana Maria Navarro, Simone Cristina dos Santos, Josilene da Costa, Oliver Zancul Prado, Joao Maroco
Summary: This study surveyed Brazilian psychologists in different phases of the COVID-19 pandemic to identify their characteristics, care practices, concerns, and symptoms. The results showed that psychologists experienced high prevalence of mental health symptoms and a lack of self-care during the pandemic.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Obstetrics & Gynecology
Cindy H. Liu, Sunah Hyun, Carmina Erdei, Leena Mittal
Summary: The study aimed to identify risk and protective factors related to general prenatal distress and COVID-19-specific prenatal distress among U.S. pregnant women during the COVID-19 pandemic. Findings highlighted the need for interventions such as mindfulness-based therapy and the importance of financial assistance and support for pregnant women during this period.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2022)
Article
Genetics & Heredity
Katarzyna Kowalczyk, Magdalena Bartnik-Glaska, Marta Smyk, Izabela Plaskota, Joanna Bernaciak, Marta Kedzior, Barbara Wisniowiecka-Kowalnik, Marta Deperas, Justyna Domaradzka, Alicja Luszczek, Daria Dutkiewicz, Agata Kozar, Dominika Grad, Magdalena Niemiec, Kamila Ziemkiewicz, Roza Magdziak, Natalia Braun-Walicka, Artur Barczyk, Maciej Geremek, Jennifer Castaneda, Anna Kutkowska-Kazmierczak, Pawel Wlasienko, Krystyna Jakubow-Durska, Marzena Debska, Anna Kucinska-Chahwan, Szymon Kozlowski, Boyana Mikulska, Tadeusz Issat, Tomasz Roszkowski, Agnieszka Nawara-Baran, Agata Runge, Anna Jakubiuk-Tomaszuk, Anna Kruczek, Ewa Kostyk, Grzegorz Pietras, Janusz Limon, Jerzy Zwolinski, Karolina Ochman, Tomasz Szajner, Piotr Wegrzyn, Miroslaw Wielgos, Maria Sasiadek, Ewa Obersztyn, Beata Anna Nowakowska
Summary: The aim of this study was to determine the suitability of the aCGH technique for prenatal diagnosis and assess the frequency of chromosomal aberrations not included in the diagnostic report. The study included 7400 prenatal cases and found a 27.2% chromosomal aberration detection rate, with 71.2% being numerical aberrations and 28.8% being structural aberrations. Clinically significant CNVs were detected in 6.8% of cases, and variants of unknown clinical significance were found in 0.7% of cases. The detection rate of clinically significant submicroscopic CNVs varied among different indications for invasive testing.
Review
Neurosciences
Laura Ziuzia-Januszewska, Marcin Januszewski
Summary: This review summarizes the current understanding of the pathogenesis of smell impairment in COVID-19 and suggests potential avenues for future research. Multiple theories have been proposed, including sensorineural damage, infection of olfactory epithelium support cells, and disruption of olfactory pathways. However, the exact mechanisms are still not fully elucidated and require further investigation.
Article
Medicine, Research & Experimental
Marcin Januszewski, Laura Ziuzia-Januszewska, Alicja A. Jakimiuk, Tomasz Oleksik, Marek Pokulniewicz, Waldemar Wierzba, Krzysztof Kozlowski, Artur J. Jakimiuk
Summary: The objective of this retrospective study was to determine the correlation between patient biomarkers on hospital admission and disease severity in pregnant women with COVID-19. The analysis revealed that lung involvement on CT scans and laboratory indicators such as lymphocytopenia and elevated inflammatory markers were associated with greater disease severity. Further research with a larger cohort is needed to determine the practical application of these findings.
BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES
(2022)
Article
Immunology
Urszula Nowacka, Paulina Malarkiewicz, Janusz Sierdzinski, Aleksandra Januszaniec, Szymon Kozlowski, Tadeusz Issat
Summary: Pregnancy is a known factor for vaccine hesitancy, and this study investigated the vaccine uptake and hesitancy rate among pregnant and postpartum individuals. The results showed that only 59.8% of the participants were offered a vaccine by healthcare professionals. Women with higher levels of education, positive feedback about vaccination, or knowledge about COVID-19 complications in pregnancy were more likely to accept the vaccination. Hesitancy was associated with multiparity, worse educational status, and lack of previous COVID-19 infection.
Article
Biochemistry & Molecular Biology
Ewa Skarzynska, Monika Wrobel, Hanna Zborowska, Mateusz Franciszek Kolek, Grzegorz Manka, Mariusz Kiecka, Michal Lipa, Damian Warzecha, Robert Spaczynski, Piotr Piekarski, Beata Banaszewska, Artur Jakimiuk, Tadeusz Issat, Wojciech Rokita, Jakub Mlodawski, Maria Szubert, Piotr Sieroszewski, Grzegorz Raba, Kamil Szczupak, Tomasz Kluz, Marek Kluza, Miroslaw Wielgos, Barbara Lisowska-Myjak, Piotr Laudanski
Summary: The aim of this study was to investigate the relationship between lactoferrin and iron and its binding proteins in women with endometriosis. The results showed differences in lactoferrin, transferrin, ferritin, and iron levels between plasma and peritoneal fluid. Lactoferrin levels in plasma were associated with iron and transferrin in endometriosis, while lactoferrin in peritoneal fluid correlated with lactoferrin, iron, and transferrin in patients without endometriosis. The study suggests that assessing iron metabolism may be useful in diagnosing and monitoring endometriosis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Obstetrics & Gynecology
Piotr Laudanski, Gabriela Rogalska, Damian Warzecha, Michal Lipa, Grzegorz Manka, Mariusz Kiecka, Robert Spaczynski, Piotr Piekarski, Beata Banaszewska, Artur Jakimiuk, Tadeusz Issat, Wojciech Rokita, Jakub Mlodawski, Maria Szubert, Piotr Sieroszewski, Grzegorz Raba, Kamil Szczupak, Tomasz Kluz, Marek Kluza, Toomas Neuman, Priit Adler, Hedi Peterson, Andres Salumets, Miroslaw Wielgos
Summary: This study found no significant differences in autoantibody expression between patients with endometriosis and the control group, suggesting that specific autoantibodies may not play a pivotal role in the pathogenesis of this disease.
HUMAN REPRODUCTION
(2023)
Article
Biochemistry & Molecular Biology
Barbara Lisowska-Myjak, Ewa Skarzynska, Monika Wrobel, Grzegorz Manka, Mariusz Kiecka, Michal Lipa, Damian Warzecha, Robert Spaczynski, Piotr Piekarski, Beata Banaszewska, Artur Jakimiuk, Tadeusz Issat, Wojciech Rokita, Jakub Mlodawski, Maria Szubert, Piotr Sieroszewski, Grzegorz Raba, Kamil Szczupak, Tomasz Kluz, Marek Kluza, Miroslaw Wielgos, Piotr Laudanski
Summary: An evaluation of the concentrations of vitamin D-binding protein and lactoferrin in the plasma and peritoneal fluid of women with suspected endometriosis revealed a correlation, suggesting their potential role in the molecular mechanisms of the disease.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Katarzyna Pankiewicz, Tadeusz Issat
Summary: Chemerin is a versatile adipokine involved in various biological processes, including inflammation, angiogenesis, adipogenesis, energy metabolism, and oxidative stress. It plays a crucial role in the development of cardiovascular diseases, particularly in pre-eclampsia (PE). Elevated levels of blood chemerin and its placental expression are positively correlated with the severity of PE. This review provides an overview of the potential role of chemerin in PE development, focusing on its involvement in oxidative stress and endothelial dysfunction.
Article
Biochemistry & Molecular Biology
Paulina Iwaniak, Piotr Dobrowolski, Jan Wrobel, Tomasz Kluz, Artur Wdowiak, Iwona Bojar, Klaudia Stangel-Wojcikiewicz, Ewa Poleszak, Artur Jakimiuk, Marcin Misiek, Lukasz Zapala, Andrzej Wrobel
Summary: The study suggests that imperatorin has the potential to alleviate the symptoms of overactive bladder syndrome and improve bladder function and biochemical changes. Its mechanisms of action are diverse and complex, making it a promising candidate for the treatment of OAB.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Monika Wrobel, Zielinska Zuzanna, Lukasz Oldak, Aleksandra Kalicka, Grzegorz Manka, Mariusz Kiecka, Robert Z. Spaczynski, Piotr Piekarski, Beata Banaszewska, Artur Jakimiuk, Tadeusz Issat, Wojciech Rokita, Jakub Mlodawski, Maria Szubert, Piotr Sieroszewski, Grzegorz Raba, Kamil Szczupak, Tomasz Kluz, Marek Kluza, Piotr Pierzynski, Cezary Wojtyla, Michal Lipa, Damian Warzecha, Miroslaw Wielgos, Wlodzimierz Sawicki, Ewa Gorodkiewicz, Piotr Laudanski
Summary: This study evaluated the levels of circulating 20S proteasome and 20S immunoproteasome in plasma and peritoneal fluid of women with and without endometriosis. The results indicate that these markers are not useful in diagnosing the disease but suggest a potential role in its pathogenesis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Ewa Skarzynska, Klaudia Mularczyk, Tadeusz Issat, Artur Jakimiuk, Barbara Lisowska-Myjak
Summary: This study investigated the concentrations of transferrin and ferritin in meconium and found a negative correlation between birth weight and ferritin concentration, as well as a positive correlation between transferrin and ferritin concentrations in neonates with higher birth weight. Moreover, the study discovered correlations between transferrin and ferritin based on different transferrin concentration levels, as well as correlations between birth weight and transferrin-ferritin concentrations.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)