4.3 Article

COVID-19 Pandemic-Related Anxiety in Pregnant Women

出版社

MDPI
DOI: 10.3390/ijerph18147221

关键词

pregnancy; COVID-19; pandemic; coronavirus; anxiety; mental health; stress; maternal medicine

向作者/读者索取更多资源

The study aimed to assess anxiety levels in pregnant women during the COVID-19 pandemic, finding that pregnant women with COVID-19 infection had higher levels of anxiety. Risk factors for anxiety included pre-pregnancy anxiety or depression history and intentional social contact avoidance. The main concern for pregnant women was the wellbeing of their fetus.
The COVID-19 pandemic outbreak influenced general and mental health worldwide. The objective of this study was to assess the anxiety level during the COVID-19 pandemic among pregnant women and compare it between COVID-infected and non-infected groups. We prospectively assessed the daily routine and anxiety level using a bespoke questionnaire and GAD-7 scale validated for pregnant women. With logistic regression, we established possible risk factors of generalized anxiety disorder spectrum and main causes of concern. The dataset included 439 responders of our survey. Of which, 21% had COVID-19 infection during pregnancy; 38% were screened for possible generalized anxiety disorder and the proportion was higher in women who suffered from COVID-19 (48% vs. 35%, p = 0.03). Pre-pregnancy anxiety or depression diagnosis and intentional social contact avoidance increased the risk of anxiety (aOR 3.4 and 3.2). Fetal wellbeing was the main concern for 66% of the responders. The COVID-19 pandemic and related restrictions substantially altered daily lives of pregnant women, exaggerating the prevalence of anxiety compared with the pre-COVID-19 studies (38% vs. 15%). COVID-19 infection during pregnancy was associated with increased levels of generalized anxiety scores. Patient-tailored psychological support should be a mainstay of comprehensive antenatal medical care in order to avoid anxiety- and stress-related complications.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.3
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

Article Genetics & Heredity

Comparative Genomic Hybridization to Microarrays in Fetuses with High-Risk Prenatal Indications: Polish Experience with 7400 Pregnancies

Katarzyna Kowalczyk, Magdalena Bartnik-Glaska, Marta Smyk, Izabela Plaskota, Joanna Bernaciak, Marta Kedzior, Barbara Wisniowiecka-Kowalnik, Marta Deperas, Justyna Domaradzka, Alicja Luszczek, Daria Dutkiewicz, Agata Kozar, Dominika Grad, Magdalena Niemiec, Kamila Ziemkiewicz, Roza Magdziak, Natalia Braun-Walicka, Artur Barczyk, Maciej Geremek, Jennifer Castaneda, Anna Kutkowska-Kazmierczak, Pawel Wlasienko, Krystyna Jakubow-Durska, Marzena Debska, Anna Kucinska-Chahwan, Szymon Kozlowski, Boyana Mikulska, Tadeusz Issat, Tomasz Roszkowski, Agnieszka Nawara-Baran, Agata Runge, Anna Jakubiuk-Tomaszuk, Anna Kruczek, Ewa Kostyk, Grzegorz Pietras, Janusz Limon, Jerzy Zwolinski, Karolina Ochman, Tomasz Szajner, Piotr Wegrzyn, Miroslaw Wielgos, Maria Sasiadek, Ewa Obersztyn, Beata Anna Nowakowska

Summary: The aim of this study was to determine the suitability of the aCGH technique for prenatal diagnosis and assess the frequency of chromosomal aberrations not included in the diagnostic report. The study included 7400 prenatal cases and found a 27.2% chromosomal aberration detection rate, with 71.2% being numerical aberrations and 28.8% being structural aberrations. Clinically significant CNVs were detected in 6.8% of cases, and variants of unknown clinical significance were found in 0.7% of cases. The detection rate of clinically significant submicroscopic CNVs varied among different indications for invasive testing.
Review Neurosciences

Pathogenesis of Olfactory Disorders in COVID-19

Laura Ziuzia-Januszewska, Marcin Januszewski

Summary: This review summarizes the current understanding of the pathogenesis of smell impairment in COVID-19 and suggests potential avenues for future research. Multiple theories have been proposed, including sensorineural damage, infection of olfactory epithelium support cells, and disruption of olfactory pathways. However, the exact mechanisms are still not fully elucidated and require further investigation.

BRAIN SCIENCES (2022)

Article Medicine, Research & Experimental

Predictors of COVID-19 severity among pregnant patients

Marcin Januszewski, Laura Ziuzia-Januszewska, Alicja A. Jakimiuk, Tomasz Oleksik, Marek Pokulniewicz, Waldemar Wierzba, Krzysztof Kozlowski, Artur J. Jakimiuk

Summary: The objective of this retrospective study was to determine the correlation between patient biomarkers on hospital admission and disease severity in pregnant women with COVID-19. The analysis revealed that lung involvement on CT scans and laboratory indicators such as lymphocytopenia and elevated inflammatory markers were associated with greater disease severity. Further research with a larger cohort is needed to determine the practical application of these findings.

BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES (2022)

Article Immunology

COVID-19 Vaccination Status among Pregnant and Postpartum Women-A Cross-Sectional Study on More Than 1000 Individuals

Urszula Nowacka, Paulina Malarkiewicz, Janusz Sierdzinski, Aleksandra Januszaniec, Szymon Kozlowski, Tadeusz Issat

Summary: Pregnancy is a known factor for vaccine hesitancy, and this study investigated the vaccine uptake and hesitancy rate among pregnant and postpartum individuals. The results showed that only 59.8% of the participants were offered a vaccine by healthcare professionals. Women with higher levels of education, positive feedback about vaccination, or knowledge about COVID-19 complications in pregnancy were more likely to accept the vaccination. Hesitancy was associated with multiparity, worse educational status, and lack of previous COVID-19 infection.

VACCINES (2022)

Article Biochemistry & Molecular Biology

The Influence of Lactoferrin in Plasma and Peritoneal Fluid on Iron Metabolism in Women with Endometriosis

Ewa Skarzynska, Monika Wrobel, Hanna Zborowska, Mateusz Franciszek Kolek, Grzegorz Manka, Mariusz Kiecka, Michal Lipa, Damian Warzecha, Robert Spaczynski, Piotr Piekarski, Beata Banaszewska, Artur Jakimiuk, Tadeusz Issat, Wojciech Rokita, Jakub Mlodawski, Maria Szubert, Piotr Sieroszewski, Grzegorz Raba, Kamil Szczupak, Tomasz Kluz, Marek Kluza, Miroslaw Wielgos, Barbara Lisowska-Myjak, Piotr Laudanski

Summary: The aim of this study was to investigate the relationship between lactoferrin and iron and its binding proteins in women with endometriosis. The results showed differences in lactoferrin, transferrin, ferritin, and iron levels between plasma and peritoneal fluid. Lactoferrin levels in plasma were associated with iron and transferrin in endometriosis, while lactoferrin in peritoneal fluid correlated with lactoferrin, iron, and transferrin in patients without endometriosis. The study suggests that assessing iron metabolism may be useful in diagnosing and monitoring endometriosis.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Article Obstetrics & Gynecology

Autoantibody screening of plasma and peritoneal fluid of patients with endometriosis

Piotr Laudanski, Gabriela Rogalska, Damian Warzecha, Michal Lipa, Grzegorz Manka, Mariusz Kiecka, Robert Spaczynski, Piotr Piekarski, Beata Banaszewska, Artur Jakimiuk, Tadeusz Issat, Wojciech Rokita, Jakub Mlodawski, Maria Szubert, Piotr Sieroszewski, Grzegorz Raba, Kamil Szczupak, Tomasz Kluz, Marek Kluza, Toomas Neuman, Priit Adler, Hedi Peterson, Andres Salumets, Miroslaw Wielgos

Summary: This study found no significant differences in autoantibody expression between patients with endometriosis and the control group, suggesting that specific autoantibodies may not play a pivotal role in the pathogenesis of this disease.

HUMAN REPRODUCTION (2023)

Article Biochemistry & Molecular Biology

Investigation of the Changes in Concentrations of Vitamin D-Binding Protein and Lactoferin in Plasma and Peritoneal Fluid of Patients with Endometriosis

Barbara Lisowska-Myjak, Ewa Skarzynska, Monika Wrobel, Grzegorz Manka, Mariusz Kiecka, Michal Lipa, Damian Warzecha, Robert Spaczynski, Piotr Piekarski, Beata Banaszewska, Artur Jakimiuk, Tadeusz Issat, Wojciech Rokita, Jakub Mlodawski, Maria Szubert, Piotr Sieroszewski, Grzegorz Raba, Kamil Szczupak, Tomasz Kluz, Marek Kluza, Miroslaw Wielgos, Piotr Laudanski

Summary: An evaluation of the concentrations of vitamin D-binding protein and lactoferrin in the plasma and peritoneal fluid of women with suspected endometriosis revealed a correlation, suggesting their potential role in the molecular mechanisms of the disease.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Review Biochemistry & Molecular Biology

Understanding the Role of Chemerin in the Pathophysiology of Pre-Eclampsia

Katarzyna Pankiewicz, Tadeusz Issat

Summary: Chemerin is a versatile adipokine involved in various biological processes, including inflammation, angiogenesis, adipogenesis, energy metabolism, and oxidative stress. It plays a crucial role in the development of cardiovascular diseases, particularly in pre-eclampsia (PE). Elevated levels of blood chemerin and its placental expression are positively correlated with the severity of PE. This review provides an overview of the potential role of chemerin in PE development, focusing on its involvement in oxidative stress and endothelial dysfunction.

ANTIOXIDANTS (2023)

Article Biochemistry & Molecular Biology

The Assessment of the Efficacy of Imperatorin in Reducing Overactive Bladder Symptoms

Paulina Iwaniak, Piotr Dobrowolski, Jan Wrobel, Tomasz Kluz, Artur Wdowiak, Iwona Bojar, Klaudia Stangel-Wojcikiewicz, Ewa Poleszak, Artur Jakimiuk, Marcin Misiek, Lukasz Zapala, Andrzej Wrobel

Summary: The study suggests that imperatorin has the potential to alleviate the symptoms of overactive bladder syndrome and improve bladder function and biochemical changes. Its mechanisms of action are diverse and complex, making it a promising candidate for the treatment of OAB.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Article Biochemistry & Molecular Biology

Evaluation of Proteasome and Immunoproteasome Levels in Plasma and Peritoneal Fluid in Patients with Endometriosis

Monika Wrobel, Zielinska Zuzanna, Lukasz Oldak, Aleksandra Kalicka, Grzegorz Manka, Mariusz Kiecka, Robert Z. Spaczynski, Piotr Piekarski, Beata Banaszewska, Artur Jakimiuk, Tadeusz Issat, Wojciech Rokita, Jakub Mlodawski, Maria Szubert, Piotr Sieroszewski, Grzegorz Raba, Kamil Szczupak, Tomasz Kluz, Marek Kluza, Piotr Pierzynski, Cezary Wojtyla, Michal Lipa, Damian Warzecha, Miroslaw Wielgos, Wlodzimierz Sawicki, Ewa Gorodkiewicz, Piotr Laudanski

Summary: This study evaluated the levels of circulating 20S proteasome and 20S immunoproteasome in plasma and peritoneal fluid of women with and without endometriosis. The results indicate that these markers are not useful in diagnosing the disease but suggest a potential role in its pathogenesis.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Article Biochemistry & Molecular Biology

Meconium Transferrin and Ferritin as Markers of Homeostasis in the Developing Fetus

Ewa Skarzynska, Klaudia Mularczyk, Tadeusz Issat, Artur Jakimiuk, Barbara Lisowska-Myjak

Summary: This study investigated the concentrations of transferrin and ferritin in meconium and found a negative correlation between birth weight and ferritin concentration, as well as a positive correlation between transferrin and ferritin concentrations in neonates with higher birth weight. Moreover, the study discovered correlations between transferrin and ferritin based on different transferrin concentration levels, as well as correlations between birth weight and transferrin-ferritin concentrations.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

暂无数据