Intramolecular quality control: HIV-1 envelope gp160 signal-peptide cleavage as a functional folding checkpoint

A slowly cleaved viral signal peptide acts as a protein-integral immune evasion domain

(2021) Einat Seidel et al.   Nature Communications

Characterization of CNPY5 and its family members

(2019) Danny Schildknegt et al.   PROTEIN SCIENCE

The Mechanical Power of Titin Folding

(2019) Edward C. Eckels et al.   Cell Reports

Ribosome Profiling: Global Views of Translation

(2018) Nicholas T. Ingolia et al.   Cold Spring Harbor Perspectives in Biology

Structure and topology around the cleavage site regulate post-translational cleavage of the HIV-1 gp160 signal peptide

(2017) Erik Lee Snapp et al.   eLife

Co- and Post-Translational Protein Folding in the ER

(2016) Lars Ellgaard et al.   TRAFFIC

An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability

(2016) Marit J. van Gils et al.   Nature Microbiology

Force-induced remodelling of proteins and their complexes

(2015) Yun Chen et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch

(2015) Wendy R. Gordon et al.   DEVELOPMENTAL CELL

Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans

(2015) Fernando Garces et al.   IMMUNITY

Structure of Influenza Virus N7: the Last Piece of the Neuraminidase "Jigsaw" Puzzle

(2014) X. Sun et al.   JOURNAL OF VIROLOGY

Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion

(2014) Marko Gogala et al.   NATURE

Structures of an intramembrane vitamin K epoxide reductase homolog reveal control mechanisms for electron transfer

(2014) Shixuan Liu et al.   Nature Communications

Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation

(2014) Mingxi Yao et al.   Scientific Reports

Co-translational Processing of Glycoprotein 3 from Equine Arteritis Virus

(2013) Anna Karolina Matczuk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

(2013) J.-P. Julien et al.   SCIENCE

Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

(2013) D. Lyumkis et al.   SCIENCE

An Interaction Map of Endoplasmic Reticulum Chaperones and Foldases

(2012) Gregor Jansen et al.   MOLECULAR & CELLULAR PROTEOMICS

How Difficult Is It to Fold a Knotted Protein? In Silico Insights from Surface-Tethered Folding Experiments

(2012) Miguel A. Soler et al.   PLoS One

Dynamic force sensing of filamin revealed in single-molecule experiments

(2012) L. Rognoni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes

(2011) Nicholas T. Ingolia et al.   CELL

Characterization of Early EDEM1 Protein Maturation Events and Their Functional Implications

(2011) Taku Tamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enzyme Digests Eliminate Nonfunctional Env from HIV-1 Particle Surfaces, Leaving Native Env Trimers Intact and Viral Infectivity Unaffected

(2011) E. T. Crooks et al.   JOURNAL OF VIROLOGY

Stabilized HIV-1 Envelope Glycoprotein Trimers Lacking the V1V2 Domain, Obtained by Virus Evolution

(2010) Ilja Bontjer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Primary Folding Defect and Rescue of ΔF508 CFTR Emerge during Translation of the Mutant Domain

(2010) Hanneke Hoelen et al.   PLoS One

Vitamin K epoxide reductase prefers ER membrane-anchored thioredoxin-like redox partners

(2010) S. Schulman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extensive sequence turnover of the signal peptides of members of the GDF/BMP family: exploring their evolutionary landscape

(2009) Reiner A Veitia et al.   Biology Direct

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility

(2009) M. Pancera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stretching Single Talin Rod Molecules Activates Vinculin Binding

(2009) A. del Rio et al.   SCIENCE

Mechanoenzymatic Cleavage of the Ultralarge Vascular Protein von Willebrand Factor

(2009) X. Zhang et al.   SCIENCE

The Interferon-Induced Protein BST-2 Restricts HIV-1 Release and Is Downregulated from the Cell Surface by the Viral Vpu Protein

(2008) Nanette Van Damme et al.   Cell Host & Microbe

Insulin Gene Mutations as Cause of Diabetes in Children Negative for Five Type 1 Diabetes Autoantibodies

(2008) R. Bonfanti et al.   DIABETES CARE

Optimization of Human Immunodeficiency Virus Type 1 Envelope Glycoproteins with V1/V2 Deleted, Using Virus Evolution

(2008) I. Bontjer et al.   JOURNAL OF VIROLOGY

Evolution Rescues Folding of Human Immunodeficiency Virus-1 Envelope Glycoprotein GP120 Lacking a Conserved Disulfide Bond

(2008) Rogier W. Sanders et al.   MOLECULAR BIOLOGY OF THE CELL

Only Five of 10 Strictly Conserved Disulfide Bonds Are Essential for Folding and Eight for Function of the HIV-1 Envelope Glycoprotein

(2008) Eelco van Anken et al.   MOLECULAR BIOLOGY OF THE CELL

In Vivo Reduction-Oxidation State of Protein Disulfide Isomerase: The Two Active Sites Independently Occur in the Reduced and Oxidized Forms

(2007) Christian Appenzeller-Herzog et al.   ANTIOXIDANTS & REDOX SIGNALING

Protein folding in confined and crowded environments

(2007) Huan-Xiang Zhou   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS