Coordination among multiple receptor tyrosine kinase signals controls Drosophila developmental timing and body size

The Upd3 cytokine couples inflammation to maturation defects in Drosophila

(2021) Daniela Romão et al.   CURRENT BIOLOGY

Snail synchronizes endocycling in a TOR-dependent manner to coordinate entry and escape from endoreplication pausing during the Drosophila critical weight checkpoint

(2020) Jie Zeng et al.   PLOS BIOLOGY

The Corazonin-PTTH Neuronal Axis Controls Systemic Body Growth by Regulating Basal Ecdysteroid Biosynthesis in Drosophila melanogaster

(2020) Eisuke Imura et al.   CURRENT BIOLOGY

Egfr Signaling Is a Major Regulator of Ecdysone Biosynthesis in the Drosophila Prothoracic Gland

(2020) Josefa Cruz et al.   CURRENT BIOLOGY

Autophagy-Mediated Cholesterol Trafficking Controls Steroid Production

(2019) Michael J. Texada et al.   DEVELOPMENTAL CELL

AstA Signaling Functions as an Evolutionary Conserved Mechanism Timing Juvenile to Adult Transition

(2019) Derya Deveci et al.   CURRENT BIOLOGY

A Tissue- and Temporal-Specific Autophagic Switch Controls Drosophila Pre-metamorphic Nutritional Checkpoints

(2019) Xueyang Pan et al.   CURRENT BIOLOGY

Receptor Tyrosine Kinases in Development: Insights from Drosophila

(2019) Sarah Mele et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Prothoracicotropic hormone modulates environmental adaptive plasticity through the control of developmental timing

(2018) MaryJane Shimell et al.   DEVELOPMENT

An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila

(2018) David Li-Kroeger et al.   eLife

A Membrane Transporter Is Required for Steroid Hormone Uptake in Drosophila

(2018) Naoki Okamoto et al.   DEVELOPMENTAL CELL

Drosophila Jak/STAT Signaling: Regulation and Relevance in Human Cancer and Metastasis

(2018) Sunny Trivedi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Severe developmental timing defects in the prothoracicotropic hormone (PTTH)-deficient silkworm, Bombyx mori

(2017) Miwa Uchibori-Asano et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

A Drosophila Genome-Wide Screen Identifies Regulators of Steroid Hormone Production and Developmental Timing

(2016) E. Thomas Danielsen et al.   DEVELOPMENTAL CELL

Vesicle-Mediated Steroid Hormone Secretion in Drosophila melanogaster

(2015) Naoki Yamanaka et al.   CELL

Microbiota-Dependent Priming of Antiviral Intestinal Immunity in Drosophila

(2015) Christine L. Sansone et al.   Cell Host & Microbe

Drosophila Lgr3 Couples Organ Growth with Maturation and Ensures Developmental Stability

(2015) Julien Colombani et al.   CURRENT BIOLOGY

Drosophila melanogaster larvae make nutritional choices that minimize developmental time

(2015) Marisa A. Rodrigues et al.   JOURNAL OF INSECT PHYSIOLOGY

Autocrine regulation of ecdysone synthesis by β3-octopamine receptor in the prothoracic gland is essential forDrosophilametamorphosis

(2015) Yuya Ohhara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A brain circuit that synchronizes growth and maturation revealed through Dilp8 binding to Lgr3

(2015) Diana M. Vallejo et al.   SCIENCE

Dilp8 requires the neuronal relaxin receptor Lgr3 to couple growth to developmental timing

(2015) Andres Garelli et al.   Nature Communications

Plug-and-Play Genetic Access to Drosophila Cell Types using Exchangeable Exon Cassettes

(2015) Fengqiu Diao et al.   Cell Reports

A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila

(2015) Sonal Nagarkar-Jaiswal et al.   eLife

Enzymes for ecdysteroid biosynthesis: their biological functions in insects and beyond

(2014) Ryusuke Niwa et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Production of systemically circulating Hedgehog by the intestine couples nutrition to growth and development

(2014) Jonathan Rodenfels et al.   GENES & DEVELOPMENT

Serotonergic neurons respond to nutrients and regulate the timing of steroid hormone biosynthesis in Drosophila

(2014) Yuko Shimada-Niwa et al.   Nature Communications

Body size determination in insects: a review and synthesis of size- and brain-dependent and independent mechanisms

(2013) Viviane Callier et al.   BIOLOGICAL REVIEWS

Dynamic feedback circuits function as a switch for shaping a maturation-inducing steroid pulse in Drosophila

(2013) M. E. Moeller et al.   DEVELOPMENT

TheDrosophilaPlatelet-derived Growth Factor and Vascular Endothelial Growth Factor-Receptor Related (Pvr) Protein Ligands Pvf2 and Pvf3 Control Hemocyte Viability and Invasive Migration

(2013) Brendon Parsons et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroendocrine Control of Drosophila Larval Light Preference

(2013) N. Yamanaka et al.   SCIENCE

Secretion and Signaling Activities of Lipoprotein-Associated Hedgehog and Non-Sterol-Modified Hedgehog in Flies and Mammals

(2013) Wilhelm Palm et al.   PLOS BIOLOGY

Ecdysone Control of Developmental Transitions: Lessons from Drosophila Research

(2012) Naoki Yamanaka et al.   Annual Review of Entomology

Ecdysone Receptors: From the Ashburner Model to Structural Biology

(2012) Ronald J. Hill et al.   Annual Review of Entomology

Drosophila Cytokine Unpaired 2 Regulates Physiological Homeostasis by Remotely Controlling Insulin Secretion

(2012) Akhila Rajan et al.   CELL

Imaginal Discs Secrete Insulin-Like Peptide 8 to Mediate Plasticity of Growth and Maturation

(2012) A. Garelli et al.   SCIENCE

Secreted Peptide Dilp8 Coordinates Drosophila Tissue Growth with Developmental Timing

(2012) J. Colombani et al.   SCIENCE

Interaction between Differentiating Cell- and Niche-Derived Signals in Hematopoietic Progenitor Maintenance

(2011) Bama Charan Mondal et al.   CELL

Anaplastic Lymphoma Kinase Spares Organ Growth during Nutrient Restriction in Drosophila

(2011) Louise Y. Cheng et al.   CELL

Neuroendocrine regulation of Drosophila metamorphosis requires TGF /Activin signaling

(2011) Y. Y. Gibbens et al.   DEVELOPMENT

A genome-scale shRNA resource for transgenic RNAi in Drosophila

(2011) Jian-Quan Ni et al.   NATURE METHODS

The Receptor Tyrosine Kinase Alk Controls Neurofibromin Functions in Drosophila Growth and Learning

(2011) Jean Y. Gouzi et al.   PLoS Genetics

The Drosophila gap gene giant regulates ecdysone production through specification of the PTTH-producing neurons

(2010) Arpan Ghosh et al.   DEVELOPMENTAL BIOLOGY

Bombyx orcokinins are brain-gut peptides involved in the neuronal regulation of ecdysteroidogenesis

(2010) Naoki Yamanaka et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Interaction between Ras V12 and scribbled clones induces tumour growth and invasion

(2010) Ming Wu et al.   NATURE

The Insect Neuropeptide PTTH Activates Receptor Tyrosine Kinase Torso to Initiate Metamorphosis

(2009) K. F. Rewitz et al.   SCIENCE