PINK1 and parkin shape the organism-wide distribution of a deleterious mitochondrial genome

Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington disease

(2020) Sandra Franco-Iborra et al.   Autophagy

A Population Phylogenetic View of Mitochondrial Heteroplasmy

(2018) Peter R. Wilton et al.   GENETICS

The multifaceted contributions of mitochondria to cellular metabolism

(2018) Jessica B. Spinelli et al.   NATURE CELL BIOLOGY

Affinity purification of cell-specific mitochondria from whole animals resolves patterns of genetic mosaicism

(2018) Arnaud Ahier et al.   NATURE CELL BIOLOGY

Building and decoding ubiquitin chains for mitophagy

(2018) J. Wade Harper et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Population Phylogenetic View of Mitochondrial Heteroplasmy

(2018) Peter R. Wilton et al.   GENETICS

Mechanisms of mitophagy in cellular homeostasis, physiology and pathology

(2018) Konstantinos Palikaras et al.   NATURE CELL BIOLOGY

Disease‐associated tau impairs mitophagy by inhibiting Parkin translocation to mitochondria

(2018) Nadia Cummins et al.   EMBO JOURNAL

The Cellular Mitochondrial Genome Landscape in Disease

(2018) Anne Hahn et al.   TRENDS IN CELL BIOLOGY

Amyloid-β and tau complexity — towards improved biomarkers and targeted therapies

(2017) Juan Carlos Polanco et al.   Nature Reviews Neurology

Homeostatic Responses Regulate Selfish Mitochondrial Genome Dynamics in C. elegans

(2016) Bryan L. Gitschlag et al.   Cell Metabolism

Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response

(2016) Yi-Fan Lin et al.   NATURE

Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents

(2016) Dongryeol Ryu et al.   NATURE MEDICINE

Mitochondrial diseases

(2016) Gráinne S. Gorman et al.   Nature Reviews Disease Primers

Mitochondria: Biogenesis and mitophagy balance in segregation and clonal expansion of mitochondrial DNA mutations

(2015) Valerio Carelli et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

EFF-1-mediated regenerative axonal fusion requires components of the apoptotic pathway

(2015) Brent Neumann et al.   NATURE

Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans

(2015) Konstantinos Palikaras et al.   NATURE

Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress

(2015) Alicia M. Pickrell et al.   NEURON

Mitophagy confers resistance to siderophore-mediated killing byPseudomonas aeruginosa

(2015) Natalia V. Kirienko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness

(2015) P. Katajisto et al.   SCIENCE

Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin

(2014) Ghazaleh Ashrafi et al.   JOURNAL OF CELL BIOLOGY

The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy

(2014) Baris Bingol et al.   NATURE

Random and targeted transgene insertion in Caenorhabditis elegans using a modified Mos1 transposon

(2014) Christian Frøkjær-Jensen et al.   NATURE METHODS

Simultaneous Expression of Multiple Proteins Under a Single Promoter in Caenorhabditis elegans via a Versatile 2A-Based Toolkit

(2013) A. Ahier et al.   GENETICS

The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans

(2013) Louis R. Lapierre et al.   Nature Communications

Caenorhabditits elegansLRK-1 and PINK-1 Act Antagonistically in Stress Response and Neurite Outgrowth

(2009) Julia Sämann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial uncouplers act synergistically with the fumigant phosphine to disrupt mitochondrial membrane potential and cause cell death

(2008) Nicholas Valmas et al.   TOXICOLOGY