Article
Multidisciplinary Sciences
Hannah Piekarz, Catherine Langran, Parastou Donyai
Summary: The study explored factors influencing medication adherence in patients with acute myocardial infarction, revealing that patients often need to compare themselves to others, value knowledge of their medicines, have uncertain feelings towards the future, incorporate medicines into their lives, and experience reduced ability to take medication when their routine is disrupted.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, Research & Experimental
Michelle Guignet, Amanda Campbell, Jonathan Vuong, Dale Whittington, H. Steve White
Summary: This study investigated the relationship between medication nonadherence and seizure incidence using perampanel in rats. The results showed that fully adherent rats had a 50% reduction in seizure frequency, while nonadherent rats had a 54% increase. Missing a dose within a 24-hour window did not correlate with breakthrough seizures, but consistently taking the medication for every meal within 24 hours reduced the likelihood of seizure incidence.
JOURNAL OF TRANSLATIONAL MEDICINE
(2023)
Review
Health Care Sciences & Services
Peter R. Chai, Clint Vaz, Georgia R. Goodman, Hannah Albrechta, Henwei Huang, Rochelle K. Rosen, Edward W. Boyer, Kenneth H. Mayer, Conall O'Cleirigh
Summary: Digital pill systems are a novel and direct method of measuring adherence, providing instantaneous adherence support. Research based on clinical trials and qualitative investigations has shown the potential of digital pill systems in measuring medication adherence and improving adherence.
Article
Cardiac & Cardiovascular Systems
Mi-Hyang Jung, So-Young Lee, Jong-Chan Youn, Woo-Baek Chung, Sang-Hyun Ihm, Dongwoo Kang, Dae-Sung Kyoung, Hae Ok Jung, Kiyuk Chang, Ho-Joong Youn, Hokyou Lee, Danbee Kang, Juhee Cho, Hidehiro Kaneko, Hyeon Chang Kim
Summary: This study aimed to explore the association between adherence to antihypertensive medication and clinical outcomes in adult patients with cancer. Nonadherence to antihypertensive medication was found to be common in cancer patients and was associated with higher overall mortality and cardiovascular mortality, as well as an increased risk of cardiovascular events. Thus, improving adherence to antihypertensive medication is crucial in cancer patients.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Pharmacology & Pharmacy
Sara Daliri, Marcel J. Kooij, Wilma J. M. Scholte Op Reimer, Gerben Riet, Patricia Jepma, Lotte Verweij, Ron J. G. Peters, Bianca M. Buurman, Fatma Karapinar-Carkit
Summary: The multi-component intervention targeting medication adherence in older cardiac patients discharged from hospital did not significantly improve their medication adherence levels, with a potential modest positive effect only seen in those not using an MDD system. This finding requires further replication.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
Article
Peripheral Vascular Disease
Hokyou Lee, Yuichiro Yano, So Mi Jemma Cho, Ji Eun Heo, Dong-Wook Kim, Sungha Park, Donald M. Lloyd-Jones, Hyeon Chang Kim
Summary: Treatment and control rates for high blood pressure are unsatisfactory among young adults, with poor adherence to pharmacological treatment associated with higher risk for future cardiovascular events.
Article
Nursing
Reza Hajialibeigloo, Seyed Reza Mazlum, Samira Mohajer, Donald E. Morisky
Summary: The study findings indicate that the self-administration of medication programme can significantly improve medication adherence levels in cardiovascular patients and increase nurse satisfaction.
Review
Obstetrics & Gynecology
Anna Davies, Sadie Mullin, Sarah Chapman, Katie Barnard, Danya Bakhbakhi, Rachel Ion, Francesca Neuberger, Judith Standing, Abi Merriel, Abigail Fraser, Christy Burden
Summary: Sub-optimal medication adherence in pregnant women with chronic disease and pregnancy-related indications can have negative effects on maternal and perinatal outcomes. This study aimed to identify effective interventions to promote medication adherence in pregnant and planning pregnancy women and assess their impact on perinatal, maternal disease-related, and adherence outcomes.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Review
Geriatrics & Gerontology
Zachary A. Marcum, Shangqing Jiang, Jennifer L. Bacci, Todd M. Ruppar
Summary: This meta-analysis found a significant improvement in medication adherence among older adults receiving pharmacist-led interventions. Implementation of pharmacist-led interventions supported by Medicare reimbursement could ensure older adults' access to effective medication adherence support.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2021)
Review
Cardiac & Cardiovascular Systems
Martin Schulz, Ulrich Laufs
Summary: Primary medication non-adherence refers to the failure to fill a first prescription for a new medication. This aspect of reduced effectiveness of pharmacotherapy is often overlooked but significant. This review investigates the prevalence, impact, reasons, predictors, and interventions related to primary non-adherence to cardiovascular/cardiometabolic drugs. Current literature shows a high prevalence of primary non-adherence, with the overall rate exceeding 10%. Understanding the reasons behind patients' reluctance to follow evidence-based pharmacotherapy and implementing targeted interventions could lead to a reduction in cardiovascular diseases.
CLINICAL RESEARCH IN CARDIOLOGY
(2023)
Article
Medicine, General & Internal
M. N. Gynnild, R. Aakery, O. Spigset, T. Askim, M. K. Beyer, H. Ihle-Hansen, R. Munthe-Kaas, A. B. Knapskog, S. Lydersen, H. Nss, T. G. Rsstad, Y. M. Seljeseth, P. Thingstad, I Saltvedt, H. Ellekjaer
Summary: The study reported medication adherence and risk factor control following ischemic stroke. While medication persistence and adherence were high, risk factor control was suboptimal, indicating the need for a better understanding of the complex clinical setting to optimize secondary prevention strategies.
JOURNAL OF INTERNAL MEDICINE
(2021)
Article
Health Care Sciences & Services
Hung Huynh Vinh Ly, Ngoc Nguyen Minh Le, Mai Thi Thao Ha, Han Gia Diep, Anh Nhut Lam, Thao Thi Thanh Nguyen, Duyen Thi Nhan Le, Trang Thi Nhu Nguyen, Tu Thi Cam Le, Katja Taxis, Suol Thanh Pham, Khanh Duy Dang, Thang Nguyen
Summary: This study aims to evaluate medication adherence in Vietnamese patients with cardiovascular and endocrine-metabolic diseases, and finds that adherence rates are similar between the two disease groups, with financial constraint being the main reason for non-adherence.
Review
Health Care Sciences & Services
Shahd Al-Arkee, Julie Mason, Deirdre A. Lane, Larissa Fabritz, Winnie Chua, M. Sayeed Haque, Zahraa Jalal
Summary: This study evaluated the effects of mobile health apps on medication adherence and health outcomes in patients with CVD, finding that these apps tended to increase medication adherence and improve clinical outcomes. However, there is a wide variation in the design, content, and delivery of these interventions, necessitating further research to identify key components for successful apps.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Nutrition & Dietetics
Sara Malo, Maria Jose Rabanaque, Lina Maldonado, Belen Moreno-Franco, Armando Chaure-Pardos, Maria Jesus Lallana, Maria Pilar Rodrigo, Isabel Aguilar-Palacio
Summary: The study aimed to identify specific profiles of new lipid-lowering drug users based on adherence to a healthy lifestyle and medication persistence, and found that differences in adherence to lifestyle and medication recommendations for cardiovascular disease prevention influenced morbidity burden and healthcare utilization.
Article
Pharmacology & Pharmacy
Sharmila Walters, Mollika Chakravorty, Sophie McLachlan, Jessica Odone, Jennifer M. Stevenson, John Minshull, Rebekah Schiff
Summary: There is a lack of national consensus regarding the provision and initiation of multicompartment medication compliance aids (MCAs) by acute hospital Trusts in England. This leads to significant variation in care and has the potential to put MCA users at an increased risk of medication-related harm.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
