Realising the full potential of data-enabled trials in the UK: a call for action

Is health research undertaken where the burden of disease is greatest? Observational study of geographical inequalities in recruitment to research in England 2013–2018

(2020) Peter Bower et al.   BMC Medicine

Access to routinely collected health data for clinical trials – review of successful data requests to UK registries

(2020) Sarah Lensen et al.   Trials

Underrepresentation of the elderly in clinical trials, time for action

(2020) Rob J. Marum   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Faecal immunochemical tests versus colonoscopy for post-polypectomy surveillance: an accuracy, acceptability and economic study

(2019) Wendy Atkin et al.   HEALTH TECHNOLOGY ASSESSMENT

Effectiveness and safety of electronically delivered prescribing feedback and decision support on antibiotic use for respiratory illness in primary care: REDUCE cluster randomised trial

(2019) Martin C Gulliford et al.   BMJ-British Medical Journal

A review of the impact of utilising electronic medical records for clinical research recruitment

(2019) Yan See Lai et al.   Clinical Trials

Trial Forge Guidance 1: what is a Study Within A Trial (SWAT)?

(2018) Shaun Treweek et al.   Trials

Recruitment of patients with Chronic Obstructive Pulmonary Disease (COPD) from the Clinical Practice Research Datalink (CPRD) for research

(2018) Jennifer K. Quint et al.   npj Primary Care Respiratory Medicine

Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus

(2018)   NEW ENGLAND JOURNAL OF MEDICINE

Increasing Diversity in Clinical Trials: Overcoming Critical Barriers

(2018) Luther T. Clark et al.   CURRENT PROBLEMS IN CARDIOLOGY

Research waste is still a scandal—an essay by Paul Glasziou and Iain Chalmers

(2018) Paul Glasziou et al.   BMJ-British Medical Journal

Effectiveness of fluticasone furoate plus vilanterol on asthma control in clinical practice: an open-label, parallel group, randomised controlled trial

(2017) Ashley Woodcock et al.   LANCET

Efficiency and safety of varying the frequency of whole blood donation (INTERVAL): a randomised trial of 45 000 donors

(2017) Emanuele Di Angelantonio et al.   LANCET

Using routinely recorded data in the UK to assess outcomes in a randomised controlled trial: The Trials of Access

(2017) G. A. Powell et al.   Trials

Recruitment and retention of participants in randomised controlled trials: a review of trials funded and published by the United Kingdom Health Technology Assessment Programme

(2017) Stephen J Walters et al.   BMJ Open

Effectiveness of Fluticasone Furoate–Vilanterol for COPD in Clinical Practice

(2016) Jørgen Vestbo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Validation of the Recording of Acute Exacerbations of COPD in UK Primary Care Electronic Healthcare Records

(2016) Kieran J. Rothnie et al.   PLoS One

Trial unpredictability yields predictable therapy gains

(2013) Benjamin Djulbegovic et al.   NATURE

Are Routinely Collected NHS Administrative Records Suitable for Endpoint Identification in Clinical Trials? Evidence from the West of Scotland Coronary Prevention Study

(2013) Sarah J. E. Barry et al.   PLoS One

Measuring the Incidence, Causes, and Repercussions of Protocol Amendments

(2012) Kenneth A. Getz et al.   DRUG INFORMATION JOURNAL

General practice-based clinical trials in Germany - a problem analysis

(2012) Eva Hummers-Pradier et al.   Trials

Avoidable waste in the production and reporting of research evidence

(2009) Iain Chalmers et al.   LANCET

Simply no time? Barriers to GPs' participation in primary health care research

(2008) E. Hummers-Pradier et al.   FAMILY PRACTICE

Speeding up the Evaluation of New Agents in Cancer

(2008) M. K. B. Parmar et al.   JNCI-Journal of the National Cancer Institute