Alpha-synuclein increases in rodent and human spinal cord injury and promotes inflammation and tissue loss
出版年份 2021 全文链接
标题
Alpha-synuclein increases in rodent and human spinal cord injury and promotes inflammation and tissue loss
作者
关键词
-
出版物
Scientific Reports
Volume 11, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-06-03
DOI
10.1038/s41598-021-91116-3
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Transcriptomic analysis of α-synuclein knockdown after T3 spinal cord injury in rats
- (2019) Hong Zeng et al. BMC GENOMICS
- The Landscape of Gene Expression and Molecular Regulation Following Spinal Cord Hemisection in Rats
- (2019) Bin Yu et al. Frontiers in Molecular Neuroscience
- Lentivirus-mediated downregulation of α-synuclein reduces neuroinflammation and promotes functional recovery in rats with spinal cord injury
- (2019) Hong Zeng et al. Journal of Neuroinflammation
- Reducing synuclein accumulation improves neuronal survival after spinal cord injury
- (2016) Stephanie M. Fogerson et al. EXPERIMENTAL NEUROLOGY
- TLR4 Deficiency Impairs Oligodendrocyte Formation in the Injured Spinal Cord
- (2016) J. S. Church et al. JOURNAL OF NEUROSCIENCE
- Spinal Cord Injury Causes Chronic Liver Pathology in Rats
- (2015) Andrew D. Sauerbeck et al. JOURNAL OF NEUROTRAUMA
- α-Synuclein Over-Expression Induces Increased Iron Accumulation and Redistribution in Iron-Exposed Neurons
- (2015) Richard Ortega et al. MOLECULAR NEUROBIOLOGY
- Repair of spinal cord injury by inhibition of astrocyte growth and inflammatory factor synthesis through local delivery of flavopiridol in PLGA nanoparticles
- (2014) Hao Ren et al. BIOMATERIALS
- Exogenous -Synuclein Decreases Raft Partitioning of Cav2.2 Channels Inducing Dopamine Release
- (2014) G. Ronzitti et al. JOURNAL OF NEUROSCIENCE
- Presynaptic Alpha-Synuclein Aggregation in a Mouse Model of Parkinson's Disease
- (2014) K. J. Spinelli et al. JOURNAL OF NEUROSCIENCE
- Role of synucleins in traumatic brain injury — An experimental in vitro and in vivo study in mice
- (2014) Irina Surgucheva et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Formation of α-synuclein Lewy neurite–like aggregates in axons impedes the transport of distinct endosomes
- (2014) Laura A. Volpicelli-Daley et al. MOLECULAR BIOLOGY OF THE CELL
- Trifluoperazine rescues human dopaminergic cells from wild-type α-synuclein-induced toxicity
- (2014) Matthias Höllerhage et al. NEUROBIOLOGY OF AGING
- Dopamine: a parallel pathway for the modulation of spinal locomotor networks
- (2014) Simon A. Sharples et al. Frontiers in Neural Circuits
- Axonopathy in an α-Synuclein Transgenic Model of Lewy Body Disease Is Associated with Extensive Accumulation of C-Terminal–Truncated α-Synuclein
- (2013) Dora Games et al. AMERICAN JOURNAL OF PATHOLOGY
- Systemic iron chelation results in limited functional and histological recovery after traumatic spinal cord injury in rats
- (2013) Andrew Sauerbeck et al. EXPERIMENTAL NEUROLOGY
- Alpha-synuclein transfers from neurons to oligodendrocytes
- (2013) Juan F. Reyes et al. GLIA
- FOXO3 determines the accumulation of α-synuclein and controls the fate of dopaminergic neurons in the substantia nigra
- (2013) Emilda Pino et al. HUMAN MOLECULAR GENETICS
- Oxidative stress-induced posttranslational modifications of alpha-synuclein: Specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity
- (2013) Wei Xiang et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Aggregation and neurotoxicity of recombinant α-synuclein aggregates initiated by dimerization
- (2013) Alireza Roostaee et al. Molecular Neurodegeneration
- The Function of α-Synuclein
- (2013) Jacob T. Bendor et al. NEURON
- Nigrostriatal overabundance of α-synuclein leads to decreased vesicle density and deficits in dopamine release that correlate with reduced motor activity
- (2012) Meret Nora Gaugler et al. ACTA NEUROPATHOLOGICA
- Neuron-to-neuron transmission of α-synuclein fibrils through axonal transport
- (2012) Eric C. Freundt et al. ANNALS OF NEUROLOGY
- Alpha-Synuclein Posttranslational Modification and Alternative Splicing as a Trigger for Neurodegeneration
- (2012) Katrin Beyer et al. MOLECULAR NEUROBIOLOGY
- The many faces of α-synuclein: from structure and toxicity to therapeutic target
- (2012) Hilal A. Lashuel et al. NATURE REVIEWS NEUROSCIENCE
- Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo
- (2012) Elodie Angot et al. PLoS One
- Non-Resolving Aspects of Acute Inflammation after Spinal Cord Injury (SCI): Indices and Resolution Plateau
- (2011) Harald Prüss et al. BRAIN PATHOLOGY
- The PPAR alpha agonist gemfibrozil is an ineffective treatment for spinal cord injured mice
- (2011) Akshata Almad et al. EXPERIMENTAL NEUROLOGY
- Synuclein accumulation is associated with cell-specific neuronal death after spinal cord injury
- (2011) David J. Busch et al. JOURNAL OF COMPARATIVE NEUROLOGY
- The alpha-synuclein 5′untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen
- (2011) Jack T. Rogers et al. JOURNAL OF NEURAL TRANSMISSION
- Controlling Specific Locomotor Behaviors through Multidimensional Monoaminergic Modulation of Spinal Circuitries
- (2011) P. Musienko et al. JOURNAL OF NEUROSCIENCE
- Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
- (2011) Laura A. Volpicelli-Daley et al. NEURON
- Alpha-Synuclein Is a Cellular Ferrireductase
- (2011) Paul Davies et al. PLoS One
- Curcumin reduces α-synuclein induced cytotoxicity in Parkinson's disease cell model
- (2010) Min S Wang et al. BMC NEUROSCIENCE
- Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies
- (2010) He-Jin Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Transgenic Overexpression of α-Synuclein and Not Its Related Pathology Associates with Complex I Inhibition
- (2010) Virginie Loeb et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Alpha-Synuclein Aggregation Induced by Brief Ischemia Negatively Impacts Neuronal Survival in vivo: A Study in [A30P]alpha-Synuclein Transgenic Mouse
- (2010) Isin Unal-Cevik et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Increased iron levels correlate with the selective nigral dopaminergic neuron degeneration in Parkinson’s disease
- (2010) Zhanyun Lv et al. JOURNAL OF NEURAL TRANSMISSION
- α-Synuclein expression is induced by depolarization and cyclic AMP in enteric neurons
- (2010) Sébastien Paillusson et al. JOURNAL OF NEUROCHEMISTRY
- A Pathologic Cascade Leading to Synaptic Dysfunction in -Synuclein-Induced Neurodegeneration
- (2010) D. A. Scott et al. JOURNAL OF NEUROSCIENCE
- Cell-Produced -Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival
- (2010) E. Emmanouilidou et al. JOURNAL OF NEUROSCIENCE
- Dose- and time-dependent α-synuclein aggregation induced by ferric iron in SK-N-SH cells
- (2010) Wen-Jing Li et al. Neuroscience Bulletin
- Astrocytic expression of Parkinson's disease-related A53T α-synuclein causes neurodegeneration in mice
- (2010) Xing-Long Gu et al. Molecular Brain
- Astrocytes initiate inflammation in the injured mouse spinal cord by promoting the entry of neutrophils and inflammatory monocytes in an IL-1 receptor/MyD88-dependent fashion
- (2009) Isabelle Pineau et al. BRAIN BEHAVIOR AND IMMUNITY
- Induction of Parkinson Disease-Related Proteins in Motor Neurons after Transient Spinal Cord Ischemia in Rabbits
- (2009) Masahiro Sakurai et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Chronic expression of PPAR-δ by oligodendrocyte lineage cells in the injured rat spinal cord
- (2009) Akshata Almad et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Evaluation of α-synuclein immunohistochemical methods used by invited experts
- (2008) Thomas G. Beach et al. ACTA NEUROPATHOLOGICA
- Synergistic Effects of D1/5 and 5-HT1A/7 Receptor Agonists on Locomotor Movement Induction in Complete Spinal Cord–Transected Mice
- (2008) Nicolas P. Lapointe et al. JOURNAL OF NEUROPHYSIOLOGY
- Analyzing real-time PCR data by the comparative CT method
- (2008) Thomas D Schmittgen et al. Nature Protocols
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started