mTOR inhibitor temsirolimus and MEK1/2 inhibitor U0126 promote chromosomal instability and cell type-dependent phenotype changes of glioblastoma cells

出版年份 2016 全文链接

标题

mTOR inhibitor temsirolimus and MEK1/2 inhibitor U0126 promote chromosomal instability and cell type-dependent phenotype changes of glioblastoma cells

作者

关键词

Aneuploidy, BRAF, Chromosomal instability, Drug resistance, Karyotype, ERK1/2, Everolimus, Glioblastoma, Glioma, mTOR complex, MEK1/2, Rapamycin, Targeted therapy, Temsirolimus, Tumor evolution, Tumor heterogeneity, U0126

出版物

GENE

Volume 579, Issue 1, Pages 58-68

出版商

Elsevier BV

发表日期

2016-01-01

DOI

10.1016/j.gene.2015.12.064

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