The first trial of CIM331, a humanized antihuman interleukin-31 receptor A antibody, in healthy volunteers and patients with atopic dermatitis to evaluate safety, tolerability and pharmacokinetics of a single dose in a randomized, double-blind, placebo-co

Ethnic sensitivity assessment – pharmacokinetic comparability between Japanese and non-Japanese healthy subjects on selected mAbs

(2014) Soichiro Matsushima et al.   Expert Opinion on Drug Metabolism & Toxicology

Distribution of IL-31 and its receptor expressing cells in skin of atopic dermatitis

(2014) Atsuhiko Kato et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Guidelines of care for the management of atopic dermatitis

(2014) Robert Sidbury et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Guidelines of care for the management of atopic dermatitis

(2014) Lawrence F. Eichenfield et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Dupilumab Treatment in Adults with Moderate-to-Severe Atopic Dermatitis

(2014) Lisa A. Beck et al.   NEW ENGLAND JOURNAL OF MEDICINE

A comparison of radio-frequency biomotion sensors and actigraphy versus polysomnography for the assessment of sleep in normal subjects

(2014) Emer O’Hare et al.   Sleep and Breathing

Systemic therapy for atopic dermatitis

(2013) D. Simon et al.   ALLERGY

Interleukin-31 does not induce immediate itch in atopic dermatitis patients and healthy controls after skin challenge

(2013) T. Hawro et al.   ALLERGY

A single dose of interleukin-31 (IL-31) causes continuous itch-associated scratching behaviour in mice

(2013) Iwao Arai et al.   EXPERIMENTAL DERMATOLOGY

A sensory neuron–expressed IL-31 receptor mediates T helper cell–dependent itch: Involvement of TRPV1 and TRPA1

(2013) Ferda Cevikbas et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A comprehensive review of the pharmacokinetics of approved therapeutic monoclonal antibodies in Japan: Are Japanese phase I studies still needed?

(2013) Koji Chiba et al.   JOURNAL OF CLINICAL PHARMACOLOGY

New concept of the pathogenesis of atopic dermatitis: Interplay among the barrier, allergy, and pruritus as a trinity

(2013) Kenji Kabashima   JOURNAL OF DERMATOLOGICAL SCIENCE

Impact of disease severity on work productivity and activity impairment in Japanese patients with atopic dermatitis

(2013) Chizuko Yano et al.   JOURNAL OF DERMATOLOGY

IL-31 Expression by Inflammatory Cells is Preferentially Elevated in Atopic Dermatitis

(2012) GFL Hofbauer et al.   ACTA DERMATO-VENEREOLOGICA

Increased frequencies of IL-31-producing T cells are found in chronic atopic dermatitis skin

(2012) Krisztina Szegedi et al.   EXPERIMENTAL DERMATOLOGY

Dendritic Cells Activated by IFN- /STAT1 Express IL-31 Receptor and Release Proinflammatory Mediators upon IL-31 Treatment

(2012) J. Horejs-Hoeck et al.   JOURNAL OF IMMUNOLOGY

Health-related quality of life in patients with atopic dermatitis

(2011) Nataša MAKSIMOVIĆ et al.   JOURNAL OF DERMATOLOGY

What causes itch in atopic dermatitis?

(2008) Gil Yosipovitch et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Anti-interleukin-31-antibodies ameliorate scratching behaviour in NC/Nga mice: a model of atopic dermatitis

(2008) Øystein Grimstad et al.   EXPERIMENTAL DERMATOLOGY

Atopic Dermatitis

(2008) Thomas Bieber   NEW ENGLAND JOURNAL OF MEDICINE

Muscular exercise can cause highly pathological liver function tests in healthy men

(2007) Jonas Pettersson et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY