A prometaphase mechanism of securin destruction is essential for meiotic progression in mouse oocytes

Cyclin A1 in Oocytes Prevents Chromosome Segregation And Anaphase Entry

(2020) Lenka Radonova et al.   Scientific Reports

Cyclin B3 is required for metaphase to anaphase transition in oocyte meiosis I

(2019) Yufei Li et al.   JOURNAL OF CELL BIOLOGY

Cyclin B3 promotes anaphase I onset in oocyte meiosis

(2019) Mehmet E. Karasu et al.   JOURNAL OF CELL BIOLOGY

Aneuploidy in Oocytes Is Prevented by Sustained CDK1 Activity through Degron Masking in Cyclin B1

(2019) Mark D. Levasseur et al.   DEVELOPMENTAL CELL

ProTAME Arrest in Mammalian Oocytes and Embryos Does Not Require Spindle Assembly Checkpoint Activity

(2019) Lenka Radonova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cohesin cleavage by separase is enhanced by a substrate motif distinct from the cleavage site

(2019) Laura E. Rosen et al.   Nature Communications

Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C

(2019) Suyang Zhang et al.   Nature Communications

Structural interconversions of the anaphase-promoting complex/cyclosome (APC/C) regulate cell cycle transitions

(2019) David Barford   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structural biology of the separase–securin complex with crucial roles in chromosome segregation

(2018) Shukun Luo et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Cdk1 inactivation induces post-anaphase-onset spindle migration and membrane protrusion required for extreme asymmetry in mouse oocytes

(2018) Zhe Wei et al.   Nature Communications

Molecular mechanism for the regulation of yeast separase by securin

(2017) Shukun Luo et al.   NATURE

Cryo-EM structure of a metazoan separase–securin complex at near-atomic resolution

(2017) Andreas Boland et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Maternal age-dependent APC/C-mediated decrease in securin causes premature sister chromatid separation in meiosis II

(2017) Ibtissem Nabti et al.   Nature Communications

Cryo-EM structure of a metazoan separase–securin complex at near-atomic resolution

(2017) Andreas Boland et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Chromosome Cohesion Established by Rec8-Cohesin in Fetal Oocytes Is Maintained without Detectable Turnover in Oocytes Arrested for Months in Mice

(2016) Sabrina Burkhardt et al.   CURRENT BIOLOGY

Building a Regulatory Network with Short Linear Sequence Motifs: Lessons from the Degrons of the Anaphase-Promoting Complex

(2016) Norman E. Davey et al.   MOLECULAR CELL

Structural basis of cohesin cleavage by separase

(2016) Zhonghui Lin et al.   NATURE

The ABBA Motif Binds APC/C Activators and Is Shared by APC/C Substrates and Regulators

(2015) Barbara Di Fiore et al.   DEVELOPMENTAL CELL

Positive and Negative Regulation of Vertebrate Separase by Cdk1-Cyclin B1 May Explain Why Securin Is Dispensable

(2015) Susanne Hellmuth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Robust Ordering of Anaphase Events by Adaptive Thresholds and Competing Degradation Pathways

(2015) Julia Kamenz et al.   MOLECULAR CELL

Error-prone chromosome-mediated spindle assembly favors chromosome segregation defects in human oocytes

(2015) Z. Holubcova et al.   SCIENCE

SiR–Hoechst is a far-red DNA stain for live-cell nanoscopy

(2015) Gražvydas Lukinavičius et al.   Nature Communications

Dependency of the Spindle Assembly Checkpoint on Cdk1 Renders the Anaphase Transition Irreversible

(2014) Ahmed Rattani et al.   CURRENT BIOLOGY

PP2A delays APC/C-dependent degradation of separase-associated but not free securin

(2014) S. Hellmuth et al.   EMBO JOURNAL

Multiple mechanisms determine the order of APC/C substrate degradation in mitosis

(2014) Dan Lu et al.   JOURNAL OF CELL BIOLOGY

Molecular architecture and mechanism of the anaphase-promoting complex

(2014) Leifu Chang et al.   NATURE

Insights into Degron Recognition by APC/C Coactivators from the Structure of an Acm1-Cdh1 Complex

(2013) Jun He et al.   MOLECULAR CELL

One-Step Sequence- and Ligation-Independent Cloning as a Rapid and Versatile Cloning Method for Functional Genomics Studies

(2012) Jae-Yeon Jeong et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The Spindle Assembly Checkpoint

(2012) Pablo Lara-Gonzalez et al.   CURRENT BIOLOGY

Timing of anaphase-promoting complex activation in mouse oocytes is predicted by microtubule-kinetochore attachment but not by bivalent alignment or tension

(2012) S. I. R. Lane et al.   DEVELOPMENT

Separase Sensor Reveals Dual Roles for Separase Coordinating Cohesin Cleavage and Cdk1 Inhibition

(2012) Norihisa Shindo et al.   DEVELOPMENTAL CELL

Age-related aneuploidy through cohesion exhaustion

(2012) Rolf Jessberger   EMBO REPORTS

Structure of the mitotic checkpoint complex

(2012) William C. H. Chao et al.   NATURE

Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore

(2012) Emily A. Foley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Error-prone mammalian female meiosis from silencing the spindle assembly checkpoint without normal interkinetochore tension

(2012) A. Kolano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural analysis of human Cdc20 supports multisite degron recognition by APC/C

(2012) W. Tian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-Dependent Susceptibility of Chromosome Cohesion to Premature Separase Activation in Mouse Oocytes1

(2011) Teresa Chiang et al.   BIOLOGY OF REPRODUCTION

Rosetta FlexPepDock web server—high resolution modeling of peptide–protein interactions

(2011) Nir London et al.   NUCLEIC ACIDS RESEARCH

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Evidence that Weakened Centromere Cohesion Is a Leading Cause of Age-Related Aneuploidy in Oocytes

(2010) Teresa Chiang et al.   CURRENT BIOLOGY

Age-Related Meiotic Segregation Errors in Mammalian Oocytes Are Preceded by Depletion of Cohesin and Sgo2

(2010) Lisa Martine Lister et al.   CURRENT BIOLOGY

Rec8-containing cohesin maintains bivalents without turnover during the growing phase of mouse oocytes

(2010) K. Tachibana-Konwalski et al.   GENES & DEVELOPMENT

UBE2S drives elongation of K11-linked ubiquitin chains by the Anaphase-Promoting Complex

(2010) T. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sub-angstrom modeling of complexes between flexible peptides and globular proteins

(2010) Barak Raveh et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Defective cohesin is associated with age-dependent misaligned chromosomes in oocytes

(2010) Lin Liu et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Regulation of APC/C Activity in Oocytes by a Bub1-Dependent Spindle Assembly Checkpoint

(2009) Barry E. McGuinness et al.   CURRENT BIOLOGY

A Spindle Assembly Checkpoint Protein Functions in Prophase I Arrest and Prometaphase Progression

(2009) H. Homer et al.   SCIENCE

Regulation of APC/C Activators in Mitosis and Meiosis

(2008) Jillian A. Pesin et al.   Annual Review of Cell and Developmental Biology

Mechanism of Ubiquitin-Chain Formation by the Human Anaphase-Promoting Complex

(2008) Lingyan Jin et al.   CELL

Securin and not CDK1/cyclin B1 regulates sister chromatid disjunction during meiosis II in mouse eggs

(2008) Ibtissem Nabti et al.   DEVELOPMENTAL BIOLOGY

Securin regulates entry into M-phase by modulating the stability of cyclin B

(2008) Petros Marangos et al.   NATURE CELL BIOLOGY