Human Gut Faecalibacterium prausnitzii Deploys a Highly Efficient Conserved System To Cross-Feed on β-Mannan-Derived Oligosaccharides

A pair of esterases from a commensal gut bacterium remove acetylations from all positions on complex β-mannans

(2020) Leszek Michalak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synergy between Cell Surface Glycosidases and Glycan-Binding Proteins Dictates the Utilization of Specific Beta(1,3)-Glucans by Human Gut Bacteroides

(2020) Guillaume Déjean et al.   mBio

Wood-Derived Dietary Fibers Promote Beneficial Human Gut Microbiota

(2019) Sabina Leanti La Rosa et al.   mSphere

The human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans

(2019) Sabina Leanti La Rosa et al.   Nature Communications

A surface exposed GH26 β-mannanase from Bacteroides ovatus: structure, role and phylogenetic analysis of BoMan26B

(2019) Viktoria Bågenholm et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two binding proteins of the ABC transporter that confers growth of Bifidobacterium animalis subsp. lactis ATCC27673 on β‐mannan possess distinct manno‐oligosaccharide‐binding profiles

(2019) M. Ejby et al.   MOLECULAR MICROBIOLOGY

Magic-BLAST, an accurate RNA-seq aligner for long and short reads

(2019) Grzegorz M. Boratyn et al.   BMC BIOINFORMATICS

Gut Microbiome Biomarkers and Functional Diversity Within an Amazonian Semi-Nomadic Hunter–Gatherer Group

(2019) Liliane Costa Conteville et al.   Frontiers in Microbiology

Structural insights into the catalytic mechanism of a novel glycoside hydrolase family 113 β-1,4-mannanase from Amphibacillus xylanus

(2018) Xin You et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential bacterial capture and transport preferences facilitate co-growth on dietary xylan in the human gut

(2018) Maria Louise Leth et al.   Nature Microbiology

Strains, functions and dynamics in the expanded Human Microbiome Project

(2017) Jason Lloyd-Price et al.   NATURE

Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention

(2017) Ruixin Liu et al.   NATURE MEDICINE

Seasonal cycling in the gut microbiome of the Hadza hunter-gatherers of Tanzania

(2017) Samuel A. Smits et al.   SCIENCE

Analyses of gut microbiota and plasma bile acids enable stratification of patients for antidiabetic treatment

(2017) Yanyun Gu et al.   Nature Communications

Molecular Mechanism by which Prominent Human Gut Bacteroidetes Utilize Mixed-Linkage Beta-Glucans, Major Health-Promoting Cereal Polysaccharides

(2017) Kazune Tamura et al.   Cell Reports

Functional Characterization of Novel Faecalibacterium prausnitzii Strains Isolated from Healthy Volunteers: A Step Forward in the Use of F. prausnitzii as a Next-Generation Probiotic

(2017) Rebeca Martín et al.   Frontiers in Microbiology

Two distinct metacommunities characterize the gut microbiota in Crohn's disease patients

(2017) Qing He et al.   GigaScience

The gut microbiome of healthy Japanese and its microbial and functional uniqueness

(2016) Suguru Nishijima et al.   DNA RESEARCH

Changes in the Abundance of Faecalibacterium prausnitzii Phylogroups I and II in the Intestinal Mucosa of Inflammatory Bowel Disease and Patients with Colorectal Cancer

(2016) Mireia Lopez-Siles et al.   INFLAMMATORY BOWEL DISEASES

Galactomannan Catabolism Conferred by a Polysaccharide Utilization Locus ofBacteroides ovatus

(2016) Viktoria Bågenholm et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polysaccharide Degradation by the Intestinal Microbiota and Its Influence on Human Health and Disease

(2016) Darrell W. Cockburn et al.   JOURNAL OF MOLECULAR BIOLOGY

Comparative In silico Analysis of Butyrate Production Pathways in Gut Commensals and Pathogens

(2016) Swadha Anand et al.   Frontiers in Microbiology

Faecalibacterium prausnitzii prevents physiological damages in a chronic low-grade inflammation murine model

(2015) Rebeca Martín et al.   BMC MICROBIOLOGY

Mannan biotechnology: from biofuels to health

(2015) Montarop Yamabhai et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer

(2015) Jun Yu et al.   GUT

Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism

(2015) Fiona Cuskin et al.   NATURE

The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment

(2015) Xuan Zhang et al.   NATURE MEDICINE

Molecular details of a starch utilization pathway in the human gut symbiontEubacterium rectale

(2014) Darrell W. Cockburn et al.   MOLECULAR MICROBIOLOGY

A discrete genetic locus confers xyloglucan metabolism in select human gut Bacteroidetes

(2014) Johan Larsbrink et al.   NATURE

The gut microbiota, bacterial metabolites and colorectal cancer

(2014) Petra Louis et al.   NATURE REVIEWS MICROBIOLOGY

Gut microbiome of the Hadza hunter-gatherers

(2014) Stephanie L. Schnorr et al.   Nature Communications

Bacteroides thetaiotaomicron and Faecalibacterium prausnitzii influence the production of mucus glycans and the development of goblet cells in the colonic epithelium of a gnotobiotic model rodent

(2013) Laura Wrzosek et al.   BMC BIOLOGY

Faecalibacterium prausnitzii and human intestinal health

(2013) S Miquel et al.   CURRENT OPINION IN MICROBIOLOGY

Richness of human gut microbiome correlates with metabolic markers

(2013) Emmanuelle Le Chatelier et al.   NATURE

The abundance and variety of carbohydrate-active enzymes in the human gut microbiota

(2013) Abdessamad El Kaoutari et al.   NATURE REVIEWS MICROBIOLOGY

The Molecular Mechanism of Thermostable α-Galactosidases AgaA and AgaB Explained by X-ray Crystallography and Mutational Studies

(2012) Romain Merceron et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolic Mechanism of Mannan in a Ruminal Bacterium,Ruminococcus albus, Involving Two Mannoside Phosphorylases and Cellobiose 2-Epimerase

(2012) Ryosuke Kawahara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

How glycan metabolism shapes the human gut microbiota

(2012) Nicole M. Koropatkin et al.   NATURE REVIEWS MICROBIOLOGY

Cultured Representatives of Two Major Phylogroups of Human Colonic Faecalibacterium prausnitzii Can Utilize Pectin, Uronic Acids, and Host-Derived Substrates for Growth

(2011) Mireia Lopez-Siles et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

New microbial mannan catabolic pathway that involves a novel mannosylglucose phosphorylase

(2011) Takeshi Senoura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

Hemicelluloses

(2010) Henrik Vibe Scheller et al.   Annual Review of Plant Biology

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Dominant and diet-responsive groups of bacteria within the human colonic microbiota

(2010) Alan W Walker et al.   ISME Journal

Transfer of carbohydrate-active enzymes from marine bacteria to Japanese gut microbiota

(2010) Jan-Hendrik Hehemann et al.   NATURE

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Complex Glycan Catabolism by the Human Gut Microbiota: The Bacteroidetes Sus-like Paradigm

(2009) Eric C. Martens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Real-time polymerase chain reaction quantification of specific butyrate-producing bacteria,DesulfovibrioandEnterococcus faecalisin the feces of patients with colorectal cancer

(2008) Ramadass Balamurugan et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

(2008) H. Sokol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA