Review
Gastroenterology & Hepatology
Pichamol Jirapinyo, Nitin Kumar, Monica Saumoy, Andrew Copland, Shelby Sullivan
Summary: A subcommittee of the ASGE conducted a systematic review and meta-analysis, which was approved by the Governing Board after peer review. The PIVI initiative aims to establish thresholds for endoscopic technologies and promote the appropriate use of technologies meeting these standards.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Gastroenterology & Hepatology
D. Chamil Codipilly, Lovekirat Dhaliwal, Meher Oberoi, Parth Gandhi, Michele L. Johnson, Ramona M. Lansing, W. Scott Harmsen, Kenneth K. Wang, Prasad G. Iyer
Summary: Endoscopic submucosal dissection (ESD) achieves higher complete remission rates of dysplasia in Barrett's esophagus patients compared to cap-assisted endoscopic mucosal resection (cEMR), although rates of complete remission of intestinal metaplasia (CRIM) at 2 years and complication rates are similar between the two groups.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Review
Medicine, General & Internal
Francesco Maione, Alessia Chini, Rosa Maione, Michele Manigrasso, Alessandra Marello, Gianluca Cassese, Nicola Gennarelli, Marco Milone, Giovanni Domenico De Palma
Summary: Barrett's Esophagus is a common condition associated with chronic gastroesophageal reflux disease and has a higher risk of developing esophageal adenocarcinoma. Low and high-grade dysplasia precede neoplastic transformation in this condition. The evaluation of low-grade dysplastic esophageal mucosa is still controversial, but endoscopic surveillance and minimally invasive endoscopic treatments such as endoscopic mucosal resection and radiofrequency ablation are available options. Cryotherapy ablation and argon plasma coagulation are novel endoscopic treatments with high eradication rates and fewer complications and post-procedural pain.
Article
Gastroenterology & Hepatology
Dennis Yang, William King, Hiroyuki Aihara, Michael S. Karasik, Saowanee Ngamruengphong, Abdul Aziz Aadam, Mohamed O. Othman, Neil Sharma, Ian S. Grimm, Alaa Rostom, B. Joseph Elmunzer, Salmaan A. Jawaid, Yaseen B. Perbtani, Brenda J. Hoffman, Ashwin S. Akki, Alexander Schlachterman, Roxana M. Coman, Andrew Y. Wang, Peter V. Draganov
Summary: This study found that ESD can change the diagnosis in patients with BE visible neoplasia, particularly in those with suspected invasive disease. Lesions in the distal esophagus and gastroesophageal junction, as well as prior radiofrequency ablation, were predictors of change in histologic diagnosis.
GASTROINTESTINAL ENDOSCOPY
(2022)
Article
Gastroenterology & Hepatology
Allon Kahn, Julia Crook, Michael G. Heckman, Mikolaj A. Wieczorek, Sarmed Sami, Diana Snyder, Siddharth Agarwal, Jose Santiago, Jacobo Ortiz Fernandez-Sordo, W. Keith Tan, Ramona Lansing, Kenneth K. Wang, Krish Ragunath, Massimiliano DiPietro, Herbert Wolfsen, Francisco Ramirez, David Fleischer, Cadman L. Leggett, Prasad G. Iyer
Summary: This study proposes optimal surveillance intervals after complete eradication of intestinal metaplasia (CE-IM) based on a multicenter international cohort, aiming to reduce the endoscopic burden for patients.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Gastroenterology & Hepatology
Quinn S. Solfisburg, Sarmed S. Sami, Joel Gabre, Ali Soroush, Lovekirat Dhaliwal, Claire Beveridge, Zhezhen Jin, John M. Poneros, Gary W. Falk, Gregory G. Ginsberg, Kenneth K. Wang, Charles J. Lightdale, Prasad G. Iyer, Julian A. Abrams
Summary: Recurrence of intestinal metaplasia at the gastroesophageal junction (GEJIM) after endoscopic eradication of Barrett's esophagus (BE) is common, but not associated with an increased risk of subsequent dysplasia. Older age and longer initial BE length are independently associated with recurrence.
GASTROINTESTINAL ENDOSCOPY
(2021)
Review
Gastroenterology & Hepatology
John J. McGoran, Krish Ragunath
Summary: Barrett's esophagus is a precursor to esophageal adenocarcinoma, and endoscopic surveillance followed by endoscopic eradication therapy is the current practice. The mantra of 'Detect-Resect-Ablate' guides the therapeutic approach, emphasizing the importance of high-quality endoscopy in identifying associated pathology and preventing dysplasia recurrence. The review discusses current practices, pitfalls, complications, and future perspectives in this field, with a focus on bridging clinical practice differences between Western and Asian nations.
DIGESTIVE ENDOSCOPY
(2021)
Article
Gastroenterology & Hepatology
Swathi Eluri, Anna Paterson, Brianna N. Lauren, Maria O'Donovan, Pradeep Bhandari, Massimiliano di Pietro, Minyi Lee, Rehan Haidry, Laurence Lovat, Krish Ragunath, Chin Hur, Rebecca C. Fitzgerald, Nicholas J. Shaheen
Summary: This study assessed the application value of Cytosponge in BE patients after RFA. The results showed that Cytosponge testing is a cost-effective surveillance method and is strongly associated with residual BE after ablation.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Multidisciplinary Sciences
Arvind J. Trindade, Jianying Zhang, Kara L. Raphael, Jiejing Qiu, John Hauschild, Petros C. Benias
Summary: This retrospective observational study examined the utilization of endoscopic ablation therapy and esophagectomy in patients with Barrett's esophagus. The study found an increasing trend in the utilization of ablation therapy, while esophagectomy showed a decreasing trend. These findings suggest that endoscopic ablation therapy has become the predominant method of treatment for Barrett's esophagus with dysplasia.
SCIENTIFIC REPORTS
(2022)
Article
Gastroenterology & Hepatology
Kazuaki Norita, Tomoyuki Koike, Masahiro Saito, Hirohiko Shinkai, Reiko Ami, Yasuhiko Abe, Naohiro Dairaku, Yoshifumi Inomata, Shoichi Kayaba, Fumitake Ishiyama, Tomoyuki Oikawa, Motoki Ohyauchi, Hirotaka Ito, Sho Asonuma, Tatsuya Hoshi, Katsuaki Kato, Shuichi Ohara, Yosuke Shimodaira, Kenta Watanabe, Tooru Shimosegawa, Atsushi Masamune, Katsunori Iijima
Summary: This study followed 98 patients with Barrett's esophagus (BE) of maximum length ≥ 2 cm in Japan for over 5 years and found that the incidence of esophageal adenocarcinoma (EAC) was 0.47% per year, lower than the previously reported 1.2% per year. Further large-scale studies are needed to validate these results.
DIGESTIVE ENDOSCOPY
(2021)
Article
Gastroenterology & Hepatology
Vani Konda, Rhonda F. Souza, Kerry B. Dunbar, Jason C. Mills, Daniel S. Kim, Robert D. Odze, Stuart J. Spechler
Summary: This study aimed to characterize the early endoscopic and histologic features of radiofrequency ablation (RFA) wound healing in patients with Barrett's esophagus (BE). The results showed that squamous re-epithelialization of RFA wounds not only progressed through squamous cells extending from the proximal wound edge, but also through islands of squamous epithelium sprouting throughout the ablated segment. Additionally, subepithelial glandular structures associated with the squamous islands were found to increase post-RFA. Furthermore, subsquamous intestinal metaplasia (SSIM) was detected in biopsies of patients during the healing process. This study provides insights into the mechanisms of esophageal metaplasia and the healing of RFA wounds.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Gastroenterology & Hepatology
Mathew Vithayathil, Ines Modolell, Jacobo Ortiz-Fernandez-Sordo, Apostolos Pappas, Wladyslaw Januszewicz, Maria O'Donovan, Michele Bianchi, Jonathan. R. R. White, Philip Kaye, Krish Ragunath, Massimiliano di Pietro
Summary: For patients with Barrett's esophagus without clearly visible dysplastic lesions, longer procedural time is associated with a higher dysplasia detection rate. Adequate time is needed to perform high-quality surveillance and maximize dysplasia detection.
Article
Gastroenterology & Hepatology
Wen Pan, Xujia Li, Weijia Wang, Linjing Zhou, Jiali Wu, Tao Ren, Chao Liu, Muhan Lv, Song Su, Yong Tang
Summary: A deep learning method was developed to automatically identify Barrett's esophagus (BE) scopes in endoscopic images, showing satisfactory performance with IOU values of 0.56 (GEJ) and 0.82 (SCJ). The algorithm is promising for accurate segmentation of BE scopes, matching manual human assessment results.
BMC GASTROENTEROLOGY
(2021)
Article
Surgery
Mohammad Kermansaravi, Bassem Amr, Ali Kabir, Amir Zare, Seidamir Pasha Tabaeian, Foolad Eghbali, Abdolreza Pazouki, Radwan Kassir
Summary: This study aimed to evaluate the occurrence of gastroesophageal reflux disease (GERD) and Barrett's esophagus (BE) in patients who underwent sleeve gastrectomy (SG). The results showed that after 5 years, 29.5% of patients developed reflux esophagitis and the incidence of BE was 5.7%.
Article
Biochemical Research Methods
Anouk L. Post, Albert J. de Groof, Xu U. Zhang, Anne-Fre Swager, Kiki N. Fockens, Roos E. Pouw, Bas L. A. M. Weusten, Dirk J. Faber, Daniel M. de Bruin, Jacques J. G. H. M. Bergman, Ton G. van Leeuwen, Henricus J. C. M. Sterenborg, Wouter L. Curvers
Summary: This study utilized multidiameter single fiber reflectance spectroscopy (MDSFR) to improve surveillance of Barrett's esophagus, developing a classifier based on logistic regression analysis to predict the presence of neoplasia in other parts of the Barrett's segment with high sensitivity and specificity.
JOURNAL OF BIOPHOTONICS
(2021)
Article
Gastroenterology & Hepatology
Cassandra D. L. Fritz, Zachary L. Smith, Jeffrey Elsner, Thomas Hollander, Dayna Early, Vladimir Kushnir
DIGESTIVE DISEASES AND SCIENCES
(2018)
Article
Gastroenterology & Hepatology
Zachary L. Smith, Martin H. Gregory, Jeffrey Elsner, Bader A. Alajlan, Divya Kodali, Thomas Hollander, Gregory S. Sayuk, Gabriel D. Lang, Koushik K. Das, Daniel K. Mullady, Dayna S. Early, Vladimir M. Kushnir
DIGESTIVE ENDOSCOPY
(2019)
Letter
Gastroenterology & Hepatology
Zachary L. Smith, Kulwinder S. Dua
GASTROINTESTINAL ENDOSCOPY
(2019)
Article
Gastroenterology & Hepatology
Zachary L. Smith, Austin L. Chiang, Deborah Bowman, Michael B. Wallace
GASTROINTESTINAL ENDOSCOPY
(2019)
Review
Anesthesiology
Zachary L. Smith, Koushik K. Das, Vladimir M. Kushnir
CURRENT OPINION IN ANESTHESIOLOGY
(2019)
Article
Gastroenterology & Hepatology
Zachary L. Smith, Daniel K. Mullady, Gabriel D. Lang, Koushik K. Das, Robert M. Hovis, Riddhi S. Patel, Thomas G. Hollander, Jeffery Elsner, Catherine Ifune, Vladimir M. Kushnir
GASTROINTESTINAL ENDOSCOPY
(2019)
Article
Surgery
Zachary L. Smith, Kenneth H. Park, Ernesto M. Llano, Kianoush Donboli, Lea Fayad, Samuel Han, Lorna Kang, Robert T. Simril, Riddhi Patel, Thomas Hollander, Melinda C. Rogers, B. Joseph Elmunzer, Uzma D. Siddiqui, A. Aziz Aadam, Daniel K. Mullady, Gabriel D. Lang, Koushik K. Das, Laith H. Jamil, Simon K. Lo, Srinivas Gaddam, Christopher G. Chapman, Rajesh N. Keswani, Sachin Wani, Gregory A. Cote, Vivek Kumbhari, Vladimir M. Kushnir
SURGERY FOR OBESITY AND RELATED DISEASES
(2019)
Article
Gastroenterology & Hepatology
Raj Shah, Sagarika Satyavada, Mayada Ismail, Michael Kurin, Zachary L. Smith, Gregory S. Cooper, Amitabh Chak
GASTROINTESTINAL ENDOSCOPY
(2020)
Article
Surgery
Abbinaya Elangovan, Raj Shah, Zachary L. Smith
Summary: Despite a modest increase in the prevalence of anti-obesity medications in the last 10 years, they remain significantly underutilized, especially among adults with obesity. Further studies addressing the barriers to anti-obesity pharmacotherapy might help in increasing the utilization of these medications.
Article
Gastroenterology & Hepatology
Dhairya Mehta, Adam H. Loutfy, Vladimir M. Kushnir, Ashley L. Faulx, Zachary L. Smith
Summary: The cost-effectiveness analysis of cold endoscopic mucosal resection (EMR) compared to hot EMR for large sessile colorectal polyps (LSCPs) showed that cold EMR is the dominant strategy with lower cost and fewer days of lost productivity. A complete transition to cold EMR for LSCPs in the USA could result in an annual cost saving approaching US$7 million to Medicare beneficiaries.
Article
Gastroenterology & Hepatology
Zachary L. Smith, Sagarika Satyavada, Roberto Simons-Linares, Shaffer R. S. Mok, Belen Martinez Moreno, Jose Ramon Aparicio, Prabhleen Chahal
Summary: This study compared the performance of glucose and CEA concentrations in differentiating MNPC. The results showed that intracystic glucose concentration is superior to CEA concentration, and glucose has the advantages of low cost and ease of implementation.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Gastroenterology & Hepatology
Zachary L. Smith, Raj Shah, B. Joseph Elmunzer, Amitabh Chak
Summary: A sustained decrease in the utilization of endoscopic sphincterotomy for patients with Sphincter of Oddi Dysfunction (SOD) was observed, highlighting the importance of high-quality, multi-center, randomized controlled trials in driving evidence-based changes in clinical practice.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Gastroenterology & Hepatology
Komal Khoja, Omar Sadiq, Phillip R. Chisholm, Kulwinder S. Dua, Srivats Madhavan, Zachary L. Smith
Summary: A study found that patients with acute pancreatitis have a higher incidence of new mental health disorders (MHDs) and pharmacotherapy use at one year after the episode.
Article
Gastroenterology & Hepatology
Zachary L. Smith, Katelin B. Nickel, Margaret A. Olsen, John J. Vargo, Vladimir M. Kushnir
FRONTLINE GASTROENTEROLOGY
(2020)
Meeting Abstract
Gastroenterology & Hepatology
Zachary L. Smith, Vasian Markollari, Katelin B. Nickel, Margaret A. Olsen, John J. Vargo, Vladimir Kushnir
GASTROINTESTINAL ENDOSCOPY
(2018)