Targeting CD276 by CAR-T cells induces regression of esophagus squamous cell carcinoma in xenograft mouse models
出版年份 2021 全文链接
标题
Targeting CD276 by CAR-T cells induces regression of esophagus squamous cell carcinoma in xenograft mouse models
作者
关键词
Esophageal cancer, CD276, CAR-T cell, Co-stimulation, Patient-derived xenograft
出版物
Translational Oncology
Volume 14, Issue 8, Pages 101138
出版商
Elsevier BV
发表日期
2021-05-28
DOI
10.1016/j.tranon.2021.101138
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Anti-BCMA chimeric antigen receptors with fully human heavy-chain-only antigen recognition domains
- (2020) Norris Lam et al. Nature Communications
- Cancer statistics, 2019
- (2019) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- CAR T cells targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors
- (2019) Robbie G. Majzner et al. CLINICAL CANCER RESEARCH
- Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells
- (2019) Hongwei Du et al. CANCER CELL
- Etiology, Cancer Stem cells and Potential Diagnostic Biomarkers for Esophageal Cancer
- (2019) Kuancan Liu et al. CANCER LETTERS
- Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells
- (2019) Yuxuan Miao et al. CELL
- GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis
- (2019) Zefang Tang et al. NUCLEIC ACIDS RESEARCH
- Multi-region sequencing unveils novel actionable targets and spatial heterogeneity in esophageal squamous cell carcinoma
- (2019) Ting Yan et al. Nature Communications
- Engineering strategies to overcome the current roadblocks in CAR T cell therapy
- (2019) Sarwish Rafiq et al. Nature Reviews Clinical Oncology
- In Vivo Expansion and Antitumor Activity of Coinfused CD28- and 4-1BB-Engineered CAR-T Cells in Patients with B Cell Leukemia
- (2018) Zhi Cheng et al. MOLECULAR THERAPY
- Chimeric Antigen Receptor Therapy
- (2018) Carl H. June et al. NEW ENGLAND JOURNAL OF MEDICINE
- Constitutive and TNFα-inducible expression of chondroitin sulfate proteoglycan 4 in glioblastoma and neurospheres: Implications for CAR-T cell therapy
- (2018) Serena Pellegatta et al. Science Translational Medicine
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Phase I Escalating-Dose Trial of CAR-T Therapy Targeting CEA + Metastatic Colorectal Cancers
- (2017) Chengcheng Zhang et al. MOLECULAR THERAPY
- Distinct Signaling of Coreceptors Regulates Specific Metabolism Pathways and Impacts Memory Development in CAR T Cells
- (2016) Omkar U. Kawalekar et al. IMMUNITY
- HER2aberrations and heterogeneity in cancers of the digestive system: Implications for pathologists and gastroenterologists
- (2016) Nicola Fusco et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Structural Design of Engineered Costimulation Determines Tumor Rejection Kinetics and Persistence of CAR T Cells
- (2015) Zeguo Zhao et al. CANCER CELL
- Maintaining Tumor Heterogeneity in Patient-Derived Tumor Xenografts
- (2015) J. W. Cassidy et al. CANCER RESEARCH
- Humanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3
- (2015) Mahiuddin Ahmed et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glycoprotein B7-H3 overexpression and aberrant glycosylation in oral cancer and immune response
- (2015) Jung-Tsu Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expression levels of HER2 and MRP1 are not prognostic factors of long-term survival in 829 patients with esophageal squamous cell carcinoma
- (2015) YONG CHEN et al. Oncology Letters
- Interim results of an ongoing Phase I, dose escalation study of MGA271 (Fc-optimized humanized anti-B7-H3 monoclonal antibody) in patients with refractory B7-H3-expressing neoplasms or neoplasms whose vasculature expresses B7-H3
- (2015) John Powderly et al. Journal for ImmunoTherapy of Cancer
- Cancer survival in China, 2003-2005: A population-based study
- (2014) Hongmei Zeng et al. INTERNATIONAL JOURNAL OF CANCER
- Esophageal Carcinoma
- (2014) Anil K. Rustgi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Epigenetic regulation of CD271, a potential cancer stem cell marker associated with chemoresistance and metastatic capacity
- (2014) SULAN LI et al. ONCOLOGY REPORTS
- Safety profile of long-term intraventricular access devices in pediatric patients receiving radioimmunotherapy for central nervous system malignancies
- (2014) Kim Kramer et al. PEDIATRIC BLOOD & CANCER
- Inhibition of Tumor Growth and Metastasis in Non-Small Cell Lung Cancer by LY2801653, an Inhibitor of Several Oncokinases, Including MET
- (2013) W. Wu et al. CLINICAL CANCER RESEARCH
- Gene amplification of EGFR, HER2, FGFR2 and MET in esophageal squamous cell carcinoma
- (2013) HIROAKI KATO et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Genome engineering using the CRISPR-Cas9 system
- (2013) F Ann Ran et al. Nature Protocols
- RhoA modulates functional and physical interaction between ROCK1 and Erk1/2 in selenite-induced apoptosis of leukaemia cells
- (2013) F Li et al. Cell Death & Disease
- Development of an Fc-Enhanced Anti-B7-H3 Monoclonal Antibody with Potent Antitumor Activity
- (2012) D. Loo et al. CLINICAL CANCER RESEARCH
- Immunobiological Characterization of Cancer Stem Cells Isolated from Glioblastoma Patients
- (2010) T. Di Tomaso et al. CLINICAL CANCER RESEARCH
- Expression of Immunosuppresive B7-H3 Ligand by Hormone-Treated Prostate Cancer Tumors and Metastases
- (2009) G. Chavin et al. CLINICAL CANCER RESEARCH
- Construction and Preclinical Evaluation of an Anti-CD19 Chimeric Antigen Receptor
- (2009) James N. Kochenderfer et al. JOURNAL OF IMMUNOTHERAPY
- Compartmental intrathecal radioimmunotherapy: results for treatment for metastatic CNS neuroblastoma
- (2009) Kim Kramer et al. JOURNAL OF NEURO-ONCOLOGY
- Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains
- (2009) C. Carpenito et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Soluble CD276 (B7-H3) is released from monocytes, dendritic cells and activated T cells and is detectable in normal human serum
- (2008) Guangbo Zhang et al. IMMUNOLOGY
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