Metribuzin-induced non-adverse liver changes result in rodent-specific non-adverse thyroid effects via uridine 5′-diphospho-glucuronosyltransferase (UDPGT, UGT) modulation

Alternatives to statistical decision trees in regulatory (eco-)toxicological bioassays

(2020) Felix M. Kluxen et al.   ARCHIVES OF TOXICOLOGY

Weight of evidence and human relevance evaluation of the benfluralin mode of action in rodents (part I): Liver carcinogenesis

(2020) Christian Strupp et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

“New statistics” in regulatory toxicology?

(2020) Felix M. Kluxen   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Use compatibility intervals in regulatory toxicology

(2020) Ludwig A. Hothorn et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Scatter plotting as a simple tool to analyse relative organ to body weight in toxicological bioassays

(2019) Felix M. Kluxen   ARCHIVES OF TOXICOLOGY

High-Throughput Screening and Quantitative Chemical Ranking for Sodium-Iodide Symporter Inhibitors in ToxCast Phase I Chemical Library

(2018) Jun Wang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Human relevance of follicular thyroid tumors in rodents caused by non-genotoxic substances

(2018) Ruediger Bartsch et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Approaches for grouping of pesticides into cumulative assessment groups for risk assessment of pesticide residues in food

(2017) Thomas Colnot et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Mechanisms of xenobiotic receptor activation: Direct vs. indirect

(2016) Bryan Mackowiak et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Characterizing “Adversity” of Pathology Findings in Nonclinical Toxicity Studies

(2016) Xavier Palazzi et al.   TOXICOLOGIC PATHOLOGY

Is It Adverse, Nonadverse, Adaptive, or Artifact?

(2016) Arun R. Pandiri et al.   TOXICOLOGIC PATHOLOGY

The inhibition of UDP-glucuronosyltransferases (UGTs) by vitamin A

(2016) Xin Liu et al.   XENOBIOTICA

Regulation of gene expression by CAR: an update

(2015) Kaoru Kobayashi et al.   ARCHIVES OF TOXICOLOGY

The Diversity of Mechanisms Influenced by Transthyretin in Neurobiology: Development, Disease and Endocrine Disruption

(2015) B. Alshehri et al.   JOURNAL OF NEUROENDOCRINOLOGY

Mode of action and human relevance of pronamide-induced rat thyroid tumors

(2015) Sabitha Papineni et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Scientific and Regulatory Policy Committee

(2015) Roy Kerlin et al.   TOXICOLOGIC PATHOLOGY

In vitroglucuronidation of aprepitant: a moderate inhibitor of UGT2B7

(2015) Larry House et al.   XENOBIOTICA

Explorations in statistics: the analysis of ratios and normalized data

(2013) Douglas Curran-Everett   ADVANCES IN PHYSIOLOGY EDUCATION

The Effect of Vitamin A Supplementation on Thyroid Function in Premenopausal Women

(2013) Mahdieh Abbasalizad Farhangi et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Interpreting Stress Responses during Routine Toxicity Studies

(2013) Nancy E. Everds et al.   TOXICOLOGIC PATHOLOGY

In vitrometabolism of thyroxine by rat and human hepatocytes

(2013) Vicki M. Richardson et al.   XENOBIOTICA

Inhibitory Effects of Commonly Used Herbal Extracts on UDP-Glucuronosyltransferase 1A4, 1A6, and 1A9 Enzyme Activities

(2011) M.-E. F. Mohamed et al.   DRUG METABOLISM AND DISPOSITION

Thyroid hormone regulation by stress and behavioral differences in adult male rats

(2011) Dana L. Helmreich et al.   HORMONES AND BEHAVIOR

Resveratrol Modulates Drug- and Carcinogen-Metabolizing Enzymes in a Healthy Volunteer Study

(2010) H.-H. S. Chow et al.   Cancer Prevention Research

IPCS Framework for Analyzing the Relevance of a Noncancer Mode of Action for Humans

(2008) Alan R. Boobis et al.   CRITICAL REVIEWS IN TOXICOLOGY

A Protective Role for Type 3 Deiodinase, a Thyroid Hormone-Inactivating Enzyme, in Cochlear Development and Auditory Function

(2008) Lily Ng et al.   ENDOCRINOLOGY