Growth of Mycobacterium tuberculosis at acidic pH depends on lipid assimilation and is accompanied by reduced GAPDH activity

The genetic requirements of fatty acid import by Mycobacterium tuberculosis within macrophages

(2019) Evgeniya V Nazarova et al.   eLife

Subcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages

(2019) Daniel J. Greenwood et al.   SCIENCE

Targeting redox heterogeneity to counteract drug tolerance in replicating Mycobacterium tuberculosis

(2019) Richa Mishra et al.   Science Translational Medicine

Genetic and metabolic regulation of Mycobacterium tuberculosis acid growth arrest

(2018) Jacob J. Baker et al.   Scientific Reports

Storage lipid studies in tuberculosis reveal that foam cell biogenesis is disease-specific

(2018) Valentina Guerrini et al.   PLoS Pathogens

Clinically prevalent mutations in Mycobacterium tuberculosis alter propionate metabolism and mediate multidrug tolerance

(2018) Nathan D. Hicks et al.   Nature Microbiology

Allosteric regulation of pyruvate kinase from Mycobacterium tuberculosis by metabolites

(2018) Jan Snášel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Glyoxylate detoxification is an essential function of malate synthase required for carbon assimilation inMycobacterium tuberculosis

(2017) Susan Puckett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Production of Superoxide in Bacteria Is Stress- and Cell State-Dependent: A Gating-Optimized Flow Cytometry Method that Minimizes ROS Measurement Artifacts with Fluorescent Dyes

(2017) Megan E. McBee et al.   Frontiers in Microbiology

The glyceraldehyde-3-phosphate dehydrogenase GapDH of Corynebacterium diphtheriae is redox-controlled by protein S-mycothiolation under oxidative stress

(2017) Melanie Hillion et al.   Scientific Reports

Mycobacterial Acid Tolerance Enables Phagolysosomal Survival and Establishment of Tuberculous Infection In Vivo

(2016) Steven Levitte et al.   Cell Host & Microbe

Acidosis Drives the Reprogramming of Fatty Acid Metabolism in Cancer Cells through Changes in Mitochondrial and Histone Acetylation

(2016) Cyril Corbet et al.   Cell Metabolism

Cytosolic thiol switches regulating basic cellular functions: GAPDH as an information hub?

(2015) Thomas Hildebrandt et al.   BIOLOGICAL CHEMISTRY

Variability in growth/no growth boundaries of 188 different Escherichia coli strains reveals that approximately 75 % have a higher growth probability under low pH conditions than E. coli O157:H7 strain ATCC 43888

(2015) L.U. Haberbeck et al.   FOOD MICROBIOLOGY

Novel Inhibitors of Cholesterol Degradation in Mycobacterium tuberculosis Reveal How the Bacterium’s Metabolism Is Constrained by the Intracellular Environment

(2015) Brian C. VanderVen et al.   PLoS Pathogens

Slow growth ofMycobacterium tuberculosisat acidic pH is regulated byphoPRand host-associated carbon sources

(2014) Jacob J. Baker et al.   MOLECULAR MICROBIOLOGY

Triosephosphate Isomerase Is Dispensable In Vitro yet Essential for Mycobacterium tuberculosis To Establish Infection

(2014) C. Trujillo et al.   mBio

IntracellularMycobacterium tuberculosisExploits Host-derived Fatty Acids to Limit Metabolic Stress

(2013) Wonsik Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolomics of Mycobacterium tuberculosis Reveals Compartmentalized Co-Catabolism of Carbon Substrates

(2010) Luiz Pedro S. de Carvalho et al.   CHEMISTRY & BIOLOGY

Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism

(2010) Mi-Jeong Kim et al.   EMBO Molecular Medicine

Gluconeogenic carbon flow of tricarboxylic acid cycle intermediates is critical for Mycobacterium tuberculosis to establish and maintain infection

(2010) J. Marrero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy

(2010) Kevin Pethe et al.   Nature Communications

Acid tolerance in Salmonella typhimurium induced by culturing in the presence of organic acids at different growth temperatures

(2009) Avelino Álvarez-Ordóñez et al.   FOOD MICROBIOLOGY

Nutrient-starved, non-replicating Mycobacterium tuberculosis requires respiration, ATP synthase and isocitrate lyase for maintenance of ATP homeostasis and viability

(2009) M. Gengenbacher et al.   MICROBIOLOGY-SGM

A membrane protein preserves intrabacterial pH in intraphagosomal Mycobacterium tuberculosis

(2008) Omar H Vandal et al.   NATURE MEDICINE

Mycobacterial persistence requires the utilization of host cholesterol

(2008) A. K. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA