Whole-blood metabolomics of dementia patients reveal classes of disease-linked metabolites

Utility of VSRAD for diagnosing Alzheimer’s disease in patients screened for dementia

(2020) Gaku Oshikubo et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Frailty markers comprise blood metabolites involved in antioxidation, cognition, and mobility

(2020) Masahiro Kameda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dementia prevention, intervention, and care: 2020 report of the Lancet Commission

(2020) Gill Livingston et al.   LANCET

Whole Blood Metabolomics in Aging Research

(2020) Hiroshi Kondoh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Diverse metabolic reactions activated during 58-hr fasting are revealed by non-targeted metabolomic analysis of human blood

(2019) Takayuki Teruya et al.   Scientific Reports

Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease

(2019) D. Allan Butterfield et al.   NATURE REVIEWS NEUROSCIENCE

Altered Redox State in Whole Blood Cells from Patients with Mild Cognitive Impairment and Alzheimer’s Disease

(2019) Irene Martínez de Toda et al.   JOURNAL OF ALZHEIMERS DISEASE

Diagnosis and Management of Dementia: Review

(2019) Zoe Arvanitakis et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Reversibility of Age-related Oxidized Free NADH Redox States in Alzheimer’s Disease Neurons by Imposed External Cys/CySS Redox Shifts

(2019) Yue Dong et al.   Scientific Reports

High Blood Caffeine Levels in MCI Linked to Lack of Progression to Dementia

(2018) Chuanhai Cao et al.   JOURNAL OF ALZHEIMERS DISEASE

Differences in Nutritional Status Between Very Mild Alzheimer's Disease Patients and Healthy Controls

(2018) Marcel G.M. Olde Rikkert et al.   JOURNAL OF ALZHEIMERS DISEASE

Indoxyl Sulfate Affects Glial Function Increasing Oxidative Stress and Neuroinflammation in Chronic Kidney Disease: Interaction between Astrocytes and Microglia

(2017) Simona Adesso et al.   Frontiers in Pharmacology

Caffeine and Adenosine

(2017) Joaquim A. Ribeiro et al.   JOURNAL OF ALZHEIMERS DISEASE

High-throughput and simultaneous quantitative analysis of homocysteine–methionine cycle metabolites and co-factors in blood plasma and cerebrospinal fluid by isotope dilution LC–MS/MS

(2016) Seu Ping Guiraud et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Ergothioneine levels in an elderly population decrease with age and incidence of cognitive decline; a risk factor for neurodegeneration?

(2016) Irwin K. Cheah et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Metabolomic profiling of brain from infants who died from Sudden Infant Death Syndrome reveals novel predictive biomarkers

(2016) S F Graham et al.   Journal of Perinatology

Individual variability in human blood metabolites identifies age-related differences

(2016) Romanas Chaleckis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drug development in Alzheimer’s disease: the path to 2025

(2016) Jeffrey Cummings et al.   Alzheimers Research & Therapy

Food-derived hydrophilic antioxidant ergothioneine is distributed to the brain and exerts antidepressant effect in mice

(2016) Noritaka Nakamichi et al.   Brain and Behavior

Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer's Dementia

(2016) Adriana Cristofano et al.   PLoS One

Metabolite profiling for the identification of altered metabolic pathways in Alzheimer's disease

(2015) Raúl González-Domínguez et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Mechanisms of Mitochondrial Dysfunction in Alzheimer’s Disease

(2015) Chris Cadonic et al.   MOLECULAR NEUROBIOLOGY

The Physiological, Biochemical, and Molecular Roles of Zinc Transporters in Zinc Homeostasis and Metabolism

(2015) Taiho Kambe et al.   PHYSIOLOGICAL REVIEWS

Whole Blood Reveals More Metabolic Detail of the Human Metabolome than Serum as Measured by 1H-NMR Spectroscopy

(2015) Kathleen A. Stringer et al.   SHOCK

Posttranslational modifications of α-tubulin in alzheimer disease

(2015) Fan Zhang et al.   Translational Neurodegeneration

Using direct infusion mass spectrometry for serum metabolomics in Alzheimer’s disease

(2014) R. González-Domínguez et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites

(2014) Romanas Chaleckis et al.   Molecular BioSystems

Plasma phospholipids identify antecedent memory impairment in older adults

(2014) Mark Mapstone et al.   NATURE MEDICINE

The worldwide economic impact of dementia 2010

(2013) Anders Wimo et al.   Alzheimers & Dementia

The microtubule-associated tau protein has intrinsic acetyltransferase activity

(2013) Todd J Cohen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Uremic toxins inhibit renal metabolic capacity through interference with glucuronidation and mitochondrial respiration

(2012) H.A.M. Mutsaers et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Evaluation of a Japanese version of the Mini-Mental State Examination in elderly persons

(2011) Yuki Ideno et al.   Geriatrics & Gerontology International

Physical Exercise as a Preventive or Disease-Modifying Treatment of Dementia and Brain Aging

(2011) J. Eric Ahlskog et al.   MAYO CLINIC PROCEEDINGS

Kynurenine and its metabolites in Alzheimer's disease patients

(2010) E Gulaj et al.   Advances in Medical Sciences

MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data

(2010) Tomáš Pluskal et al.   BMC BIOINFORMATICS

Fungal tyrosine betaine, a novel secondary metabolite from conidia of entomopathogenic Metarhizium spp. fungi

(2010) Carlos A. Carollo et al.   Fungal Biology

Improving the brain delivery of gold nanoparticles by conjugation with an amphipathic peptide

(2010) Simon Guerrero et al.   Nanomedicine

Can Cognitive Exercise Prevent the Onset of Dementia? Systematic Review of Randomized Clinical Trials with Longitudinal Follow-up

(2009) Michael Valenzuela et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

The neuropathology of probable Alzheimer disease and mild cognitive impairment

(2009) Julie A. Schneider et al.   ANNALS OF NEUROLOGY

The Role of Adenosine in Alzheimers Disease

(2009) Anisur Rahman   Current Neuropharmacology

Metabolic profiling of the fission yeast S. pombe: quantification of compounds under different temperatures and genetic perturbation

(2009) Tomáš Pluskal et al.   Molecular BioSystems

Hypaphorine, an indole alkaloid from Erythrina velutina, induced sleep on normal mice

(2008) Masaaki Ozawa et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS