标题
Addressing phenoconversion: the Achilles' heel of personalized medicine
作者
关键词
-
出版物
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
Volume 79, Issue 2, Pages 222-240
出版商
Wiley
发表日期
2014-06-10
DOI
10.1111/bcp.12441
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- CYP2D6 genotyping and tamoxifen in the treatment of post-menopausal breast cancer - a reply
- (2014) Hiltrud Brauch et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Challenges in CYP2D6 Phenotype Assignment from Genotype Data: A Critical Assessment and Call for Standardization
- (2014) J. Hicks et al. CURRENT DRUG METABOLISM
- Pharmacokinetic Drug Interaction Profiles of Proton Pump Inhibitors: An Update
- (2014) Ralph-Steven Wedemeyer et al. DRUG SAFETY
- Role of brain cytochrome P450 (CYP2D) in the metabolism of monoaminergic neurotransmitters
- (2014) Anna Haduch et al. Pharmacological Reports
- No association found betweenCYP2D6genotype and early breast cancer events in tamoxifen-treated patients
- (2013) Andrea Markkula et al. ACTA ONCOLOGICA
- Hospitalization for Hemorrhage Among Warfarin Recipients Prescribed Amiodarone
- (2013) Jason Lam et al. AMERICAN JOURNAL OF CARDIOLOGY
- Prediction of tamoxifen outcome by genetic variation of CYP2D6 in post-menopausal women with early breast cancer
- (2013) Hiltrud Brauch et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- CYP2D6 polymorphisms influence tamoxifen treatment outcomes in breast cancer patients: a meta-analysis
- (2013) Zhiyu Zeng et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- CYP2D6 Genotype and Tamoxifen Activity: Understanding Interstudy Variability in Methodological Quality
- (2013) M J Ratain et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Genetics, Epigenetics, and Regulation of Drug-Metabolizing Cytochrome P450 Enzymes
- (2013) U M Zanger et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- The (R)-omeprazole hydroxylation index reflects CYP2C19 activity in healthy Japanese volunteers
- (2013) Satoshi Yamada et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- The endogenous substrates of brain CYP2D
- (2013) Xiaoshuang Wang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Metabolism and transport of tamoxifen in relation to its effectiveness: new perspectives on an ongoing controversy
- (2013) Deirdre P Cronin-Fenton et al. Future Oncology
- Interaction of Terbinafine (Anti-fungal agent) with Perhexiline: A Case Report
- (2013) Abdul Rauf Sheikh et al. Heart Lung and Circulation
- The impact of interacting drugs on dispensed doses of warfarin in the Swedish population: A novel use of population based drug registers
- (2013) M.L. Andersson et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Dynamics and persistence of CYP2D6 inhibition by paroxetine
- (2013) J. Juřica et al. JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
- Cytochrome P450 2D6 Phenoconversion Is Common in Patients Being Treated for Depression
- (2013) Sheldon H. Preskorn et al. JOURNAL OF CLINICAL PSYCHIATRY
- Applications of CYP450 Testing in the Clinical Setting
- (2013) C. F. Samer et al. Molecular Diagnosis & Therapy
- A Randomized Trial of Genotype-Guided Dosing of Acenocoumarol and Phenprocoumon
- (2013) Talitha I. Verhoef et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Pharmacogenetic versus a Clinical Algorithm for Warfarin Dosing
- (2013) Stephen E. Kimmel et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Randomized Trial of Genotype-Guided Dosing of Warfarin
- (2013) Munir Pirmohamed et al. NEW ENGLAND JOURNAL OF MEDICINE
- Impact of CYP2C9 polymorphisms on the vulnerability to pharmacokinetic drug–drug interactions during acenocoumarol treatment
- (2013) Liliane Gschwind et al. PHARMACOGENOMICS
- Frequency and Outcomes of Concomitant Use of Proton Pump Inhibitors and Clopidogrel after Hospital Discharge
- (2013) Pedro Mas-Morey et al. THERAPIE
- Potential role of CYP2D6 in the central nervous system
- (2013) Jie Cheng et al. XENOBIOTICA
- The Discriminatory Value of CYP2D6 Genotyping in Predicting the Dextromethorphan/Dextrorphan Phenotype in Women with Breast Cancer
- (2012) Andreas Trojan et al. Breast Care
- The use of the 13C-dextromethorphan breath test for phenotyping CYP2D6 in breast cancer patients using tamoxifen: association with CYP2D6 genotype and serum endoxifen levels
- (2012) F. L. Opdam et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- CYP2D6 phenotype indicative for optimized antiestrogen efficacy associates with outcome in early breast cancer patients
- (2012) Andreas Trojan et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Impact of Genetic Polymorphisms in CYP2C9 and CYP2C19 on the Pharmacokinetics of Clinically Used Drugs
- (2012) Takeshi Hirota et al. Drug Metabolism and Pharmacokinetics
- Serum dextromethorphan/dextrorphan metabolic ratio for CYP2D6 phenotyping in clinical practice
- (2012) J. Jurica et al. JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
- CYP2D6 Genotype as a Marker for Benefit of Adjuvant Tamoxifen in Postmenopausal Women: Lessons Learned
- (2012) C. M. Kelly et al. JNCI-Journal of the National Cancer Institute
- Tamoxifen and CYP2D6: A Contradiction of Data
- (2012) D. L. Hertz et al. ONCOLOGIST
- Absence of ‘over-the-counter’ medicinal products in on-line prescription records: a risk factor of overlooking interactions in the elderly
- (2012) C. Olesen et al. PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
- Concomitant use of clopidogrel and proton pump inhibitors is not associated with major adverse cardiovascular events following coronary stent implantation
- (2011) M. Schmidt et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Variability in response to clopidogrel: how important are pharmacogenetics and drug interactions?
- (2011) Terry K. W. Ma et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Trends in primary care antidepressant prescribing 1995-2007: a longitudinal population database analysis
- (2011) Pauline Lockhart et al. BRITISH JOURNAL OF GENERAL PRACTICE
- Clinical Events as a Function of Proton Pump Inhibitor Use, Clopidogrel Use, and Cytochrome P450 2C19 Genotype in a Large Nationwide Cohort of Acute Myocardial Infarction
- (2011) Tabassome Simon et al. CIRCULATION
- Clinical Drugs Undergoing Polymorphic Metabolism by Human Cytochrome P450 2C9 and the Implication in Drug Development
- (2011) S.-M. He et al. CURRENT MEDICINAL CHEMISTRY
- Dextromethorphan As a Phenotyping Test to Predict Endoxifen Exposure in Patients on Tamoxifen Treatment
- (2011) Anne-Joy M. de Graan et al. JOURNAL OF CLINICAL ONCOLOGY
- High-risk antimicrobial prescriptions among ambulatory patients on warfarin
- (2011) M. A. Lane et al. JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
- Combined clopidogrel and proton pump inhibitor therapy is associated with higher cardiovascular event rates after percutaneous coronary intervention: a report from the BASKET trial
- (2011) T. Burkard et al. JOURNAL OF INTERNAL MEDICINE
- CYP2D6 Genotyping and Tamoxifen: An Unfinished Story in the Quest for Personalized Medicine
- (2011) Jonas A. de Souza et al. SEMINARS IN ONCOLOGY
- Cholesteryl ester transfer protein and its inhibition
- (2010) Olaf Weber et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Variability in drug metabolizing enzyme activity in HIV-infected patients
- (2010) Amanda E. Jones et al. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
- Herb–drug pharmacokinetic interactions reviewed
- (2010) Clemence Tarirai et al. Expert Opinion on Drug Metabolism & Toxicology
- Clopidogrel with or without Omeprazole in Coronary Artery Disease
- (2010) Deepak L. Bhatt et al. NEW ENGLAND JOURNAL OF MEDICINE
- Lessons for pharmacogenomics studies: association study between CYP2D6 genotype and tamoxifen response
- (2010) Kazuma Kiyotani et al. Pharmacogenetics and Genomics
- Impact of Proton Pump Inhibitors on the Effectiveness of Clopidogrel After Coronary Stent Placement: The Clopidogrel Medco Outcomes Study
- (2010) Rolf P Kreutz et al. PHARMACOTHERAPY
- [13C]-pantoprazole breath test to predict CYP2C19 phenotype and efficacy of a proton pump inhibitor, lansoprazole
- (2009) T. FURUTA et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Glucose Control by the Kidney: An Emerging Target in Diabetes
- (2009) Olivera Marsenic AMERICAN JOURNAL OF KIDNEY DISEASES
- The effect of drug interactions on bleeding risk associated with warfarin therapy in hospitalized patients
- (2009) Milka Hauta-Aho et al. ANNALS OF MEDICINE
- Relative Impact of Genotype and Enzyme Induction on the Metabolic Capacity of CYP2C9 in Healthy Volunteers
- (2009) SV Vormfelde et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Rapid Identification of the Hepatic Cytochrome P450 2C19 Activity Using a Novel and Noninvasive [13C]Pantoprazole Breath Test
- (2009) Z. Desta et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data
- (2009) NEW ENGLAND JOURNAL OF MEDICINE
- The largest prospective warfarin-treated cohort supports genetic forecasting
- (2008) M. Wadelius et al. BLOOD
- CYP2C19 pharmacogenetics in advanced cancer: compromised function independent of genotype
- (2008) N A Helsby et al. BRITISH JOURNAL OF CANCER
- CYP2D6 Phenotype Prediction From Genotype: Which System Is the Best?
- (2008) J Kirchheiner CLINICAL PHARMACOLOGY & THERAPEUTICS
- Differential Genotype Dependent Inhibition of CYP2C9 in Humans
- (2008) V. Kumar et al. DRUG METABOLISM AND DISPOSITION
- Evaluation of a [13C]-Dextromethorphan Breath Test to Assess CYP2D6 Phenotype
- (2008) J. Steven Leeder et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Terbinafine-associated inhibition of dextromethorphan metabolism in Chinese subjects
- (2003) W. M. Cai et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now