标题
Ayurveda botanicals in COVID-19 management: An in silico multi-target approach
作者
关键词
COVID 19, Drug interactions, SARS CoV 2, Inflammation, Phytochemicals, Cytokines, Enzyme metabolism, Proteases
出版物
PLoS One
Volume 16, Issue 6, Pages e0248479
出版商
Public Library of Science (PLoS)
发表日期
2021-06-12
DOI
10.1371/journal.pone.0248479
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
- (2020) Nanshan Chen et al. LANCET
- Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection
- (2020) Emmie de Wit et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2
- (2020) Renhong Yan et al. SCIENCE
- Cytokine release syndrome in severe COVID-19: interleukin-6 receptor antagonist tocilizumab may be the key to reduce mortality
- (2020) Chi Zhang et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial
- (2020) Philippe Gautret et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?
- (2020) Lei Fang et al. Lancet Respiratory Medicine
- Preliminary Estimates of the Prevalence of Selected Underlying Health Conditions Among Patients with Coronavirus Disease 2019 — United States, February 12–March 28, 2020
- (2020) et al. MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
- COVID-19 in Immunocompromised Hosts: What We Know So Far
- (2020) Monica Fung et al. CLINICAL INFECTIOUS DISEASES
- Withania somnifera (L.) Dunal: A potential therapeutic adjuvant in cancer
- (2020) Akash Saggam et al. JOURNAL OF ETHNOPHARMACOLOGY
- Investigating 11 Withanosides and Withanolides by UHPLC–PDA and Mass Fragmentation Studies from Ashwagandha (Withania somnifera)
- (2020) Aboli Girme et al. ACS Omega
- 2, 3-Dihydro-3β-methoxy Withaferin-A Lacks Anti-Metastasis Potency: Bioinformatics and Experimental Evidences
- (2019) Anupama Chaudhary et al. Scientific Reports
- PubChem 2019 update: improved access to chemical data
- (2018) Sunghwan Kim et al. NUCLEIC ACIDS RESEARCH
- Network ethnopharmacological evaluation of the immunomodulatory activity of Withania somnifera
- (2017) Uma Chandran et al. JOURNAL OF ETHNOPHARMACOLOGY
- The Role of Plant-derived Products in Pancreatitis: Experimental and Clinical Evidence
- (2017) Pratibha Anchi et al. PHYTOTHERAPY RESEARCH
- SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
- (2017) Antoine Daina et al. Scientific Reports
- Ensemble-Based Virtual Screening and Experimental Validation of Inhibitors Targeting a Novel Site of Human DNMT1
- (2016) Manali Joshi et al. Chemical Biology & Drug Design
- KEGG: new perspectives on genomes, pathways, diseases and drugs
- (2016) Minoru Kanehisa et al. NUCLEIC ACIDS RESEARCH
- HPLC/Tandem Mass Spectrometric Studies on Steroidal Saponins: An Example of Quantitative Determination of Shatavarin IV from Dietary Supplements Containing Asparagus racemosus
- (2014) Dada Patil et al. JOURNAL OF AOAC INTERNATIONAL
- Tinospora cordifolia extract modulates COX-2, iNOS, ICAM-1, pro-inflammatory cytokines and redox status in murine model of asthma
- (2014) M. Tiwari et al. JOURNAL OF ETHNOPHARMACOLOGY
- The role of ligand efficiency metrics in drug discovery
- (2014) Andrew L. Hopkins et al. NATURE REVIEWS DRUG DISCOVERY
- Withania somniferashows a protective effect in monocrotaline-induced pulmonary hypertension
- (2014) Gurpreet Kaur et al. PHARMACEUTICAL BIOLOGY
- GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit
- (2013) Sander Pronk et al. BIOINFORMATICS
- Immunity to viruses
- (2013) Thomas J. Braciale et al. IMMUNOLOGICAL REVIEWS
- Effect of Botanical Immunomodulators on Human CYP3A4 Inhibition
- (2013) Dada Patil et al. INTEGRATIVE CANCER THERAPIES
- CHARMM36 all-atom additive protein force field: Validation based on comparison to NMR data
- (2013) Jing Huang et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
- (2013) Ulrich M. Zanger et al. PHARMACOLOGY & THERAPEUTICS
- Hypoxia and inflammation are two sides of the same coin
- (2013) K. Bartels et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immunomodulatory active compounds from Tinospora cordifolia
- (2012) Upendra Sharma et al. JOURNAL OF ETHNOPHARMACOLOGY
- Plant-based Rasayana drugs from Ayurveda
- (2011) Subramani Paranthaman Balasubramani et al. Chinese Journal of Integrative Medicine
- Withaferin A down-regulates lipopolysaccharide-induced cyclooxygenase-2 expression and PGE2 production through the inhibition of STAT1/3 activation in microglial cells
- (2011) Kyoung-jin Min et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility
- (2009) Garrett M. Morris et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- The spike protein of SARS-CoV — a target for vaccine and therapeutic development
- (2009) Lanying Du et al. NATURE REVIEWS MICROBIOLOGY
- CHARMM-GUI: A web-based graphical user interface for CHARMM
- (2008) Sunhwan Jo et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Immunomodulatory activity of Asparagus racemosus on systemic Th1/Th2 immunity: Implications for immunoadjuvant potential
- (2008) Manish Gautam et al. JOURNAL OF ETHNOPHARMACOLOGY
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