The role of reciprocal fusions in MLL-r acute leukemia: studying the chromosomal translocation t(6;11)

The reciprocal world of MLL fusions: A personal view

(2020) Rolf Marschalek   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Another piece of the puzzle added to understand t(4;11) leukemia better

(2019) Rolf Marschalek   HAEMATOLOGICA

Involvement of Nectin–Afadin in the Adherens Junctions of the Corneal Endothelium

(2018) Naoki Okumura et al.   CORNEA

Prenatal origin of KRAS mutation in a child with an acute myelomonocytic leukaemia bearing the KMT2A /MLL-AFDN /MLLT4 /AF6 fusion transcript

(2018) Nellina Andriano et al.   BRITISH JOURNAL OF HAEMATOLOGY

The MLL recombinome of acute leukemias in 2017

(2017) C Meyer et al.   LEUKEMIA

An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues

(2017) M Ryan Corces et al.   NATURE METHODS

Evolution of AF6-RAS association and its implications in mixed-lineage leukemia

(2017) Matthew J. Smith et al.   Nature Communications

Optimized Sleeping Beauty transposons rapidly generate stable transgenic cell lines

(2015) Eric Kowarz et al.   Biotechnology Journal

Optimized Sleeping Beauty transposons rapidly generate stable transgenic cell lines

(2015) Eric Kowarz et al.   Biotechnology Journal

MLL-AF6 fusion oncogene sequesters AF6 into the nucleus to trigger RAS activation in myeloid leukemia

(2014) E. Manara et al.   BLOOD

Functional characterisation of different MLL fusion proteins by using inducible Sleeping Beauty vectors

(2014) K. Wächter et al.   CANCER LETTERS

Diverse functions of PHD fingers of the MLL/KMT2 subfamily

(2013) Muzaffar Ali et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Functional Specificity of CpG DNA-binding CXXC Domains in Mixed Lineage Leukemia

(2013) Laurie E. Risner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ECSASB2 mediates MLL degradation during hematopoietic differentiation

(2011) J. Wang et al.   BLOOD

The PHD3 Domain of MLL Acts as a CYP33-Regulated Switch between MLL-Mediated Activation and Repression,

(2010) Sangho Park et al.   BIOCHEMISTRY

Self-association mediated by the Ras association 1 domain of AF6 activates the oncogenic potential of MLL-AF6

(2010) M. Liedtke et al.   BLOOD

Pro Isomerization in MLL1 PHD3-Bromo Cassette Connects H3K4me Readout to CyP33 and HDAC-Mediated Repression

(2010) Zhanxin Wang et al.   CELL

Binding of the MLL PHD3 Finger to Histone H3K4me3 Is Required for MLL-Dependent Gene Transcription

(2010) Pei-Yun Chang et al.   JOURNAL OF MOLECULAR BIOLOGY

Molecular Mechanism of MLL PHD3 and RNA Recognition by the Cyp33 RRM Domain

(2010) Robert A. Hom et al.   JOURNAL OF MOLECULAR BIOLOGY

Multiple Interactions Recruit MLL1 and MLL1 Fusion Proteins to the HOXA9 Locus in Leukemogenesis

(2010) Thomas A. Milne et al.   MOLECULAR CELL

An Ash2L/RbBP5 Heterodimer Stimulates the MLL1 Methyltransferase Activity through Coordinated Substrate Interactions with the MLL1 SET Domain

(2010) Fang Cao et al.   PLoS One

Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study

(2009) B. V. Balgobind et al.   BLOOD

Phosphatidylinositol 3-kinase: a key regulator in adherens junction formation and function

(2009) Nathalie Rivard   Frontiers in Bioscience-Landmark

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

Structural Basis for the Requirement of Additional Factors for MLL1 SET Domain Activity and Recognition of Epigenetic Marks

(2009) Stacey M. Southall et al.   MOLECULAR CELL

Cell–cell junction formation: The role of Rap1 and Rap1 guanine nucleotide exchange factors

(2008) Willem-Jan Pannekoek et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Menin Critically Links MLL Proteins with LEDGF on Cancer-Associated Target Genes

(2008) Akihiko Yokoyama et al.   CANCER CELL

Alterations of the CxxC domain preclude oncogenic activation of mixed-lineage leukemia 2

(2008) C Bach et al.   ONCOGENE