标题
SMAD4 is critical in suppression of BRAF-V600E serrated tumorigenesis
作者
关键词
-
出版物
ONCOGENE
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-08-28
DOI
10.1038/s41388-021-01997-x
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Immunotherapy After Immunotherapy: Response Rescue in a Microsatellite Instability-High Colorectal Cancer Patient Post-Pembrolizumab
- (2020) Satya Das et al. Clinical Colorectal Cancer
- Analysis pipelines for cancer genome sequencing in mice
- (2020) Sebastian Lange et al. Nature Protocols
- Alterations in signaling pathways that accompany spontaneous transition to malignancy in a mouse model of BRAF mutant microsatellite stable colorectal cancer
- (2020) Alexandra M. Kane et al. NEOPLASIA
- Clinical activity of pembrolizumab in metastatic prostate cancer with microsatellite instability high (MSI-H) detected by circulating tumor DNA
- (2020) Pedro Barata et al. Journal for ImmunoTherapy of Cancer
- Pembrolizumab in Microsatellite-Instability–High Advanced Colorectal Cancer
- (2020) Thierry André et al. NEW ENGLAND JOURNAL OF MEDICINE
- Immunotherapy in colorectal cancer: rationale, challenges and potential
- (2019) Karuna Ganesh et al. Nature Reviews Gastroenterology & Hepatology
- Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and BrafV600E-Induced Tumorigenesis
- (2019) Yong Tao et al. CANCER CELL
- Clinicopathologic features and prognostic value of KRAS , NRAS , and BRAF mutations and DNA mismatch repair status: a single‐center retrospective study of 1834 Chinese patients with stage I–IV colorectal cancer
- (2019) Tian‐An Guo et al. INTERNATIONAL JOURNAL OF CANCER
- Mismatch repair deficiency/microsatellite instability-high as a predictor for anti-PD-1/PD-L1 immunotherapy efficacy
- (2019) Pengfei Zhao et al. Journal of Hematology & Oncology
- Misrepair in Context: TGFβ Regulation of DNA Repair
- (2019) Qi Liu et al. Frontiers in Oncology
- SMAD4 suppresses WNT-driven de-differentiation and oncogenesis in the differentiated gut epithelium
- (2018) Ansu O. Perekatt et al. CANCER RESEARCH
- Evaluating the Combination of Microsatellite Instability and Mutation in BRAF as Prognostic Factors for Patients With Colorectal Cancer
- (2018) Frank A. Sinicrope Clinical Gastroenterology and Hepatology
- SMAD4 gene mutation predicts poor prognosis in patients undergoing resection for colorectal liver metastases
- (2018) Takashi Mizuno et al. EJSO
- Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis
- (2018) Tamsin R M Lannagan et al. GUT
- Impact of loss-of-function mutations at the RNF43 locus on colorectal cancer development and progression
- (2018) Tsugio Eto et al. JOURNAL OF PATHOLOGY
- Prognostic value of the combination of microsatellite instability and BRAF mutation in colorectal cancer
- (2018) Yingchi Yang et al. Cancer Management and Research
- Prognostic significance of BRAF mutation alone and in combination with microsatellite instability in stage III colon cancer
- (2018) Hanumant Chouhan et al. Asia-Pacific Journal of Clinical Oncology
- In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis
- (2017) Jatin Roper et al. NATURE BIOTECHNOLOGY
- Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer
- (2017) Kevin P O'Rourke et al. NATURE BIOTECHNOLOGY
- Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids
- (2017) Arianna Fumagalli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- AACR Project GENIE: Powering Precision Medicine through an International Consortium
- (2017) Cancer Discovery
- Degree of Tissue Differentiation Dictates Susceptibility to BRAF-Driven Colorectal Cancer
- (2017) Kevin Tong et al. Cell Reports
- Microsatellite Instability
- (2017) Liisa Chang et al. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY
- BRAFV600E cooperates with CDX2 inactivation to promote serrated colorectal tumorigenesis
- (2017) Naoya Sakamoto et al. eLife
- Reduced Expression of SMAD4 Is Associated with Poor Survival in Colon Cancer
- (2016) P. Yan et al. CLINICAL CANCER RESEARCH
- Prognostic Value ofBRAF and KRAS Mutations in MSI and MSS Stage III Colon Cancer
- (2016) Julien Taieb et al. JNCI-Journal of the National Cancer Institute
- The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update
- (2016) Enis Afgan et al. NUCLEIC ACIDS RESEARCH
- Wnt signaling in cancer
- (2016) T Zhan et al. ONCOGENE
- Prognostic Value ofBRAF and KRAS Mutations in MSI and MSS Stage III Colon Cancer
- (2016) Julien Taieb et al. JNCI-Journal of the National Cancer Institute
- Sporadic Microsatellite Instability-High Colon Cancers Rarely Display Immunohistochemical Evidence of Wnt Signaling Activation
- (2015) Nicole C. Panarelli et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Combination of microsatellite instability and BRAF mutation status for subtyping colorectal cancer
- (2015) T T Seppälä et al. BRITISH JOURNAL OF CANCER
- Mismatch Repair Status and BRAF Mutation Status in Metastatic Colorectal Cancer Patients: A Pooled Analysis of the CAIRO, CAIRO2, COIN, and FOCUS Studies
- (2014) S. Venderbosch et al. CLINICAL CANCER RESEARCH
- RNF43 is frequently mutated in colorectal and endometrial cancers
- (2014) Marios Giannakis et al. NATURE GENETICS
- Transgenic expression of oncogenic BRAF induces loss of stem cells in the mouse intestine, which is antagonized by β-catenin activity
- (2014) P Riemer et al. ONCOGENE
- Serrated pathway in colorectal carcinogenesis
- (2014) Letícia Yamane WORLD JOURNAL OF GASTROENTEROLOGY
- The CIMP Phenotype inBRAFMutant Serrated Polyps from a Prospective Colonoscopy Patient Cohort
- (2014) Winnie C. Fernando et al. Gastroenterology Research and Practice
- A Genetic Progression Model of BrafV600E-Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention
- (2013) Roland Rad et al. CANCER CELL
- Serrated Lesions of the Colorectum: Review and Recommendations From an Expert Panel
- (2012) Douglas K Rex et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Smad4-mediated TGF-β signaling in tumorigenesis
- (2012) Guan Yang et al. International Journal of Biological Sciences
- Wnt Signaling in Cancer
- (2012) P. Polakis Cold Spring Harbor Perspectives in Biology
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- Smad4 Inactivation Promotes Malignancy and Drug Resistance of Colon Cancer
- (2011) P. Papageorgis et al. CANCER RESEARCH
- Smad4-Mediated Signaling Inhibits Intestinal Neoplasia by Inhibiting Expression of β-Catenin
- (2011) Tanner J. Freeman et al. GASTROENTEROLOGY
- Integrative genomics viewer
- (2011) James T Robinson et al. NATURE BIOTECHNOLOGY
- Partners in crime: the TGFβ and MAPK pathways in cancer progression
- (2011) Douglas A Chapnick et al. Cell and Bioscience
- Targeting Wnt Signaling in Colon Cancer Stem Cells
- (2010) E. M. F. de Sousa et al. CLINICAL CANCER RESEARCH
- V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation ofp16INK4a
- (2010) Linda A. S. Carragher et al. EMBO Molecular Medicine
- Role of the Serrated Pathway in Colorectal Cancer Pathogenesis
- (2010) Barbara Leggett et al. GASTROENTEROLOGY
- Smad4 restoration leads to a suppression of Wnt/β-catenin signaling activity and migration capacity in human colon carcinoma cells
- (2009) Xiaoxiao Tian et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Fast and accurate short read alignment with Burrows-Wheeler transform
- (2009) H. Li et al. BIOINFORMATICS
- Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
- (2009) Bryan T. MacDonald et al. DEVELOPMENTAL CELL
- Mouse Models of Colon Cancer
- (2009) Makoto Mark Taketo et al. GASTROENTEROLOGY
- An Msh2 Conditional Knockout Mouse for Studying Intestinal Cancer and Testing Anticancer Agents
- (2009) Melanie H. Kucherlapati et al. GASTROENTEROLOGY
- Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
- (2009) Toshiro Sato et al. NATURE
- Analysis of the Association between CIMP and BRAFV600E in Colorectal Cancer by DNA Methylation Profiling
- (2009) Toshinori Hinoue et al. PLoS One
- BRAF mutation is associated with the CpG island methylator phenotype in colorectal cancer from young patients
- (2008) Pei Woon Ang et al. CANCER LETTERS
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