Article
Medicine, General & Internal
Dorothy A. Fink, Deborah Kilday, Zhun Cao, Kelly Larson, Adrienne Smith, Craig Lipkin, Raymond Perigard, Richelle Marshall, Taryn Deirmenjian, Ashley Finke, Drew Tatum, Ning Rosenthal
Summary: This study investigated the trends and risk factors for delivery-related maternal deaths and severe maternal morbidity in the United States. The study found that maternal mortality rates decreased while severe maternal morbidity increased from 2008 to 2021. Age, race, and delivery method were associated with both outcomes.
Article
Public, Environmental & Occupational Health
Santiago Garcia-Tizon Larroca, Juan Arevalo-Serrano, Maria Ruiz Minaya, Pilar Paya Martinez, Ricardo Perez Fernandez Pacheco, Santiago Lizarraga Bonelli, Juan De Leon Luis
Summary: The study indicates that there are inequalities in maternal mortality rate in Spain depending on the maternal origin. The maternal human development index score of the country of origin could be a significant factor in estimating the risk of this complication.
Article
Obstetrics & Gynecology
Brittany Arditi, Timothy Wen, Laura E. Riley, Mary D'Alton, Nasim C. Sobhani, Alexander M. Friedman, Kartik K. Venkatesh
Summary: Pregnant women diagnosed with influenza at delivery hospitalization, especially those with chronic comorbid conditions, may face an increased risk of severe maternal morbidity, particularly influenza-related outcomes. Obstructive lung disease is associated with higher risks of acute respiratory distress syndrome and mechanical intubation and ventilation, while chronic hypertension is linked to an increased risk of acute respiratory distress syndrome.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2021)
Article
Obstetrics & Gynecology
Zenobia Brown, Choukri Messaoudi, Emily Silvia, Hallie Bleau, Ashley Meskill, Anne Flynn, Amparo C. Abel-Bey, Trever J. Ball
Summary: This study aimed to examine the effectiveness of a postpartum navigation program in reducing postpartum hospitalizations and hospitalizations due to severe maternal morbidity. The program provided standardized assessments, care plans, clinical management, and connection to services for high-risk women. Results showed that enrollees had lower rates of rehospitalization and severe maternal morbidity compared to nonenrollees, with the greatest reductions seen among Black women.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Article
Obstetrics & Gynecology
Zenobia Brown, Choukri Messaoudi, Emily Silvia, Hallie Bleau, Ashley Meskill, Anne Flynn, Amparo C. Abel -Bey, Trever J. Ball
Summary: This study aimed to examine the effectiveness of a postpartum navigation program in reducing hospitalization rates and severe maternal morbidity. The program was found to be effective in reducing both all-cause postpartum hospitalizations and hospitalizations due to severe maternal morbidity, with the greatest impact seen among Black women.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Article
Immunology
Mark W. Tenforde, Jessie Chung, Emily R. Smith, H. Keipp Talbot, Christopher H. Trabue, Richard K. Zimmerman, Fernanda P. Silveira, Manjusha Gaglani, Kempapura Murthy, Arnold S. Monto, Emily T. Martin, Huong Q. McLean, Edward A. Belongia, Lisa A. Jackson, Michael L. Jackson, Jill M. Ferdinands, Brendan Flannery, Manish M. Patel
Summary: This study compared the effectiveness of influenza vaccination between inpatient and outpatient networks in the US, finding that inpatients were older and had more high-risk conditions than outpatients. The overall vaccine effectiveness across seasons was 31% for outpatients and 36% for inpatients, with some differences observed in strain-specific VE between the two groups.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Immunology
Jill M. Ferdinands, Manjusha Gaglani, Emily T. Martin, Arnold S. Monto, Donald Middleton, Fernanda Silveira, Helen K. Talbot, Richard Zimmerman, Manish Patel
Summary: The effectiveness of influenza vaccine decreases with time since vaccination, with an absolute decline of about 8%-9% per month postvaccination.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Obstetrics & Gynecology
Blair O. O. Berger, Noelene K. K. Jeffers, Carrie Wolfson, Alison Gemmill
Summary: This study evaluated a commonly proposed explanation for the increasing rates of severe maternal morbidity (SMM) in the United States, and found that the increase was mainly driven by age-specific rates rather than shifts to older maternal age.
OBSTETRICS AND GYNECOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Abdul Mannan Khan Minhas, Sardar Hassan Ijaz, Shakeel Jamal, Sourbha S. Dani, Muhammad Shahzeb Khan, Stephen J. Greene, Marat Fudim, Haider J. Warraich, Michael D. Shapiro, Salim S. Virani, Khurram Nasir, Safi U. Khan
Summary: This 15-year national data suggests that despite a higher comorbidity burden and the recent increase in hospitalizations for HF in older patients, there has been an encouraging trend towards lower inpatient mortality, healthcare cost, and hospital length of stay among older adults in the United States.
CIRCULATION-HEART FAILURE
(2022)
Article
Medicine, General & Internal
Po-Hung Chen, Lauren Johnson, Berkeley N. Limketkai, Emily Jusuf, Jing Sun, Brian Kim, Jennifer C. Price, Tinsay A. Woreta
Summary: This study aimed to estimate the temporal trend of HCV-positive pregnancies during the opioid epidemic and identify HCV-associated maternal and perinatal outcomes. The study found that the prevalence of HCV-positive pregnancies increased significantly and was associated with increased risks for adverse perinatal outcomes.
Article
Obstetrics & Gynecology
Annie M. Dude, Kellie Schueler, L. Philip Schumm, Manoradhan Murugesan, Debra B. Stulberg
Summary: This study aimed to evaluate the association between preconception care and severe maternal morbidity among women with Medicaid. The study found that receiving contraceptive services in the year before conception and routine exams for women with chronic disease were associated with decreased odds of severe maternal morbidity.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2022)
Article
Medicine, General & Internal
Il Yun, Eun-Cheol Park, Jin Young Nam
Summary: This study found that nighttime deliveries are associated with a higher risk of severe maternal morbidity (SMM), especially at hospitals located in small cities and those with 100-499 beds.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Clinical Neurology
Anthony M. Kendle, Jason L. Salemi, Chandra L. Jackson, Daniel J. Buysse, Judette M. Louis
Summary: Using a large database, this study estimated the prevalence and trends of insomnia among pregnant women over 12 years and examined the interplay among insomnia, maternal comorbidities, and severe maternal morbidity. The study found that coded diagnosis of insomnia during pregnancy has increased over time and that insomnia is an independent predictor of severe maternal morbidity.
Article
Obstetrics & Gynecology
Alice H. Linder, Timothy Wen, Jean R. Guglielminotti, Lisa D. Levine, Yuli Y. Kim, Stephanie E. Purisch, Mary E. D'Alton, Alexander M. Friedman
Summary: The study found that maternal congenital heart disease is becoming more common among US deliveries, and the risk of severe maternal morbidity is increasing among deliveries with maternal CHD, indicating an increasing burden of risk from maternal CHD in the obstetric population.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
U. Vivian Ukah, Natalie Dayan, Brian J. Potter, Gilles Paradis, Aimina Ayoub, Nathalie Auger
Summary: Women with severe maternal morbidity have an increased risk of cardiovascular disease after pregnancy, both in the short and long term.
CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES
(2022)
Article
Obstetrics & Gynecology
Timothy Wen, Jason D. Wright, Dena Goffman, Mary E. D'Alton, William J. Mack, Frank J. Attenello, Alexander M. Friedman
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2018)
Article
Clinical Neurology
Ian A. Buchanan, Daniel A. Donoho, Arati Patel, Michelle Lin, Timothy Wen, Li Ding, Steven L. Giannotta, William J. Mack, Frank Attenello
WORLD NEUROSURGERY
(2018)
Article
Obstetrics & Gynecology
Jessica Selter, Timothy Wen, Katherine L. Palmerola, Alexander M. Friedman, Zev Williams, Eric J. Forman
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2019)
Article
Gastroenterology & Hepatology
Adam S. Faye, Timothy Wen, Ashwin N. Ananthakrishnan, Simon Lichtiger, Gilaad G. Kaplan, Alexander M. Friedman, Garrett Lawlor, Jason D. Wright, Frank J. Attenello, William J. Mack, Benjamin Lebwohl
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2020)
Article
Obstetrics & Gynecology
M. Andrikopoulou, T. Wen, J-J Sheen, N. Krenitsky, C. D. Baptiste, D. Goffman, A. P. Staniczenko, M. E. D'Alton, A. M. Friedman
Summary: This study identifies BMI, maternal age, and medical conditions as important risk factors for caesarean delivery among nulliparous, term, singleton, vertex births. Identifying these risk factors can help stratify patients into high-risk and low-risk groups for better management.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2021)
Article
Obstetrics & Gynecology
Samsiya Ona, Yongmei Huang, Cande Ananth, Cynthia Gyamfi-Bannerman, Timothy Wen, Jason D. Wright, Mary E. D'Alton, Alexander M. Friedman
Summary: Detailed evaluation of Black-serving hospitals revealed they are more likely to offer specialized medical, surgical, and safety-net services, with a higher share of Medicaid patients. Payer mix and unmeasured confounders may contribute to some of the maternal risk associated with these hospitals.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Article
Obstetrics & Gynecology
Kate E. Lee, Timothy Wen, Adam S. Faye, Yongmei Huang, Chin Hur, Alexander M. Friedman
Summary: This study found that in the United States, a diagnosis of grand multiparity during delivery hospitalizations did not increase the risk of severe maternal morbidity. Grand multiparity was associated with an increased risk of hysterectomy and shock, though the absolute increased risk for these complications was small.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Timothy Wen, Christina N. Schmidt, Nasim C. Sobhani, Jean Guglielminotti, Eliza C. Miller, Desmond Sutton, Yael Lahtermaher, Mary E. D'Alton, Alexander M. Friedman
Summary: This study analyzed the trends, risk factors, and outcomes related to hypertensive disorders of pregnancy (HDP). The prevalence of HDP doubled from 6.0% in 2000 to 12.0% in 2018, while the proportion of deliveries with risk factors for HDP increased from 9.6% to 24.6%. Adjusted models showed that HDP was associated with an increased risk of stroke (adjusted risk ratio [aRR] 15.9), acute renal failure (aRR 13.8), and acute liver injury (aRR 1.2). Acute renal failure and acute liver injury increased among deliveries with HDP, while stroke decreased.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Article
Obstetrics & Gynecology
K. Yu, A. S. Faye, T. Wen, J. R. Guglielminotti, Y. Huang, J. D. Wright, M. E. D'Alton, A. M. Friedman
Summary: The prevalence of inflammatory bowel disease is increasing among delivery hospitalizations, and disease severity is associated with adverse outcomes.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Article
Obstetrics & Gynecology
Lanbo Yang, Alexander M. Friedman, Nicole M. Krenitsky, Timothy Wen, Mary E. D'Alton, Jason D. Wright, Whitney Booker, Yongmei Huang
Summary: This study aimed to determine whether longitudinal health data of patients with chronic hypertension would contribute to organ injury or death. The analysis of 64,799 deliveries to 61,854 women found that the utilization of healthcare services before pregnancy was associated with adverse maternal outcomes.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Obstetrics & Gynecology
Anna P. P. Staniczenko, Timothy Wen, Amalia Gonzalez, Mary E. E. D'Alton, Teresa C. C. Logue, Alexander M. M. Friedman
Summary: This study found that the prevalence of unstable housing during pregnancy is low but increasing, and it is associated with adverse pregnancy outcomes.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Teresa C. C. Logue, Timothy Wen, Alexander M. M. Friedman
Summary: This study aimed to evaluate trends in substance use disorder (SUD) diagnoses during delivery hospitalizations from 2000 to 2018 and determine the risk for adverse pregnancy outcomes in the presence of cannabis and opioid use disorder diagnoses. The results showed an increasing risk for SUD across different demographic categories. Cannabis use disorder was associated with increased risk for preterm delivery and abruption and antepartum hemorrhage, while opioid use disorder was associated with risk for non-transfusion severe maternal morbidity, preterm delivery, and abruption and antepartum hemorrhage.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Letter
Obstetrics & Gynecology
Adesh Kadambi, Isabel Fulcher, Kartik Venkatesh, Jonathan S. Schor, Mark A. Clapp, Timothy Wen
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Article
Obstetrics & Gynecology
Timothy Wen, Naralys Batista, Jason D. Wright, Mary E. D'Alton, Frank J. Attenello, William J. Mack, Alexander M. Friedman
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2019)