Exogenous microbiota-derived metabolite trimethylamine N-oxide treatment alters social behaviors: Involvement of hippocampal metabolic adaptation

Baicalin ameliorates neuropathology in repeated cerebral ischemia-reperfusion injury model mice by remodeling the gut microbiota

(2020) Jianfeng Liu et al.   Aging-US

Gut Metabolite TMAO Induces Synaptic Plasticity Deficits by Promoting Endoplasmic Reticulum Stress

(2020) Manoj Govindarajulu et al.   Frontiers in Molecular Neuroscience

The gut microbiome–derived metabolite trimethylamine N-oxide modulates neuroinflammation and cognitive function with aging

(2020) Vienna E. Brunt et al.   GeroScience

Long-lasting effects of postweaning sodium butyrate exposure on social behaviors in adult mice

(2020) Penghui Zhao et al.   BRAIN RESEARCH BULLETIN

Neuroendocrine Mechanisms Involved In Sexual And Emotional Behavior.

(2019) Michele Iovino et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Fecal microbiota transplantation from chronic unpredictable mild stress mice donors affects anxiety-like and depression-like behavior in recipient mice via the gut microbiota-inflammation-brain axis

(2019) Nannan Li et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

The presence of elevated circulating trimethylamine N-oxide exaggerates postoperative cognitive dysfunction in aged rats

(2019) Fanqing Meng et al.   BEHAVIOURAL BRAIN RESEARCH

Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction

(2019) Sifan Chen et al.   Cell Metabolism

Higher Circulating Trimethylamine N-oxide Sensitizes Sevoflurane-Induced Cognitive Dysfunction in Aged Rats Probably by Downregulating Hippocampal Methionine Sulfoxide Reductase A

(2019) Liang Zhao et al.   NEUROCHEMICAL RESEARCH

Plasma trimethylamine N-oxide, a gut microbe–generated phosphatidylcholine metabolite, is associated with autism spectrum disorders

(2019) Lijuan Quan et al.   NEUROTOXICOLOGY

Trimethylamine-N -oxide promotes brain aging and cognitive impairment in mice

(2018) Dang Li et al.   AGING CELL

Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress

(2018) Yilang Ke et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neurobiology of gender identity and sexual orientation

(2018) C. E. Roselli   JOURNAL OF NEUROENDOCRINOLOGY

Trimethylamine N -oxide: A harmful, protective or diagnostic marker in lifestyle diseases?

(2018) Artur Nowiński et al.   NUTRITION

Dendritic spine anomalies and PTEN alterations in a mouse model of VPA-induced autism spectrum disorder

(2018) Usman Mahmood et al.   PHARMACOLOGICAL RESEARCH

Diet, Genetics, and the Gut Microbiome Drive Dynamic Changes in Plasma Metabolites

(2018) Shiho Fujisaka et al.   Cell Reports

Implication of Trimethylamine N-Oxide (TMAO) in Disease: Potential Biomarker or New Therapeutic Target

(2018) Manuel Janeiro et al.   Nutrients

The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer’s disease

(2018) Nicholas M. Vogt et al.   Alzheimers Research & Therapy

Sexual interaction is essential for the transformation of non-copulating rats into sexually active animals by the endocannabinoid anandamide

(2018) Ana Canseco-Alba et al.   BEHAVIOURAL BRAIN RESEARCH

Early-life adversity and brain development: Is the microbiome a missing piece of the puzzle?

(2017) S.M. O’Mahony et al.   NEUROSCIENCE

Early life experiences have complex and long-lasting effects on behavior

(2017) Bruce A. Carlson   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue

(2017) Rebecca C. Schugar et al.   Cell Reports

Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle

(2017) Lawrence Vernetti et al.   Scientific Reports

Towards understanding brain-gut-microbiome connections in Alzheimer’s disease

(2016) Rong Xu et al.   BMC Systems Biology

Neural endocannabinoid CB1 receptor expression, social status, and behavior in male European starlings

(2016) M. Susan DeVries et al.   BRAIN RESEARCH

Microbial Reconstitution Reverses Maternal Diet-Induced Social and Synaptic Deficits in Offspring

(2016) Shelly A. Buffington et al.   CELL

Diabetes is Associated with Higher Trimethylamine N-oxide Plasma Levels

(2016) M. Dambrova et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Psychological stress in early life as a predisposing factor for the development of chronic pain: Clinical and preclinical evidence and neurobiological mechanisms

(2016) Nikita N. Burke et al.   JOURNAL OF NEUROSCIENCE RESEARCH

From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways

(2016) G B Rogers et al.   MOLECULAR PSYCHIATRY

Microbes, Immunity and Behavior: Psychoneuroimmunology Meets the Microbiome

(2016) Timothy G Dinan et al.   NEUROPSYCHOPHARMACOLOGY

Long-term effects of early life stress exposure: Role of epigenetic mechanisms

(2016) Dafne M. Silberman et al.   PHARMACOLOGICAL RESEARCH

Intracerebroventricular injection of propionic acid, an enteric metabolite implicated in autism, induces social abnormalities that do not differ between seizure-prone (FAST) and seizure-resistant (SLOW) rats

(2015) Sandy R. Shultz et al.   BEHAVIOURAL BRAIN RESEARCH

Re: Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour

(2015) Lieve Desbonnet et al.   BRAIN BEHAVIOR AND IMMUNITY

Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour

(2015) Lieve Desbonnet et al.   BRAIN BEHAVIOR AND IMMUNITY

Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis

(2015) Zeneng Wang et al.   CELL

The TMAO-Generating Enzyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance

(2015) Manya Warrier et al.   Cell Reports

Neural mechanisms of social dominance

(2015) Noriya Watanabe et al.   Frontiers in Neuroscience

Endocannabinoid influence on partner preference in female rats

(2014) Nicoletta K. Memos et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Early deprivation induces competitive subordinance in C57BL/6 male mice

(2014) Seico Benner et al.   PHYSIOLOGY & BEHAVIOR

The mouse that roared: neural mechanisms of social hierarchy

(2014) Fei Wang et al.   TRENDS IN NEUROSCIENCES

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

(2013) Elaine Y. Hsiao et al.   CELL

CB1receptor signaling regulates social anxiety and memory

(2013) Y. Litvin et al.   GENES BRAIN AND BEHAVIOR

Microbiota is essential for social development in the mouse

(2013) L Desbonnet et al.   MOLECULAR PSYCHIATRY

CB1 cannabinoid receptor-mediated aggressive behavior

(2013) Marta Rodriguez-Arias et al.   NEUROPHARMACOLOGY

Serotonin signaling in the brain of adult female mice is required for sexual preference

(2013) S. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glutamine metabolism links growth factor signaling to the regulation of autophagy

(2012) Kristan E. van der Vos et al.   Autophagy

The Emergence and Representation of Knowledge about Social and Nonsocial Hierarchies

(2012) Dharshan Kumaran et al.   NEURON

Endocannabinoid Signaling and Synaptic Function

(2012) Pablo E. Castillo et al.   NEURON

Bidirectional Control of Social Hierarchy by Synaptic Efficacy in Medial Prefrontal Cortex

(2011) F. Wang et al.   SCIENCE

Early Life Stress Alters Behavior, Immunity, and Microbiota in Rats: Implications for Irritable Bowel Syndrome and Psychiatric Illnesses

(2008) Siobhain M. O'Mahony et al.   BIOLOGICAL PSYCHIATRY