Tranilast, a Transient Receptor Potential Vanilloid 2 Channel (TRPV2) Inhibitor Attenuates Amyloid β-Induced Cognitive Impairment: Possible Mechanisms

Amelioration of diabetes-induced cognitive impairment by Transient Receptor Potential Vanilloid 2 (TRPV2) channel inhibitor: Behavioral and mechanistic study

(2020) P. Thapak et al.   NEUROCHEMISTRY INTERNATIONAL

Therapeutic potential of pharmacological agents targeting TRP channels in CNS disorders

(2020) Pavan Thapak et al.   PHARMACOLOGICAL RESEARCH

TRPV2 channels mediate insulin secretion induced by cell swelling in mouse pancreatic β-cells

(2019) Toshiaki Sawatani et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Evaluation of cationic channel TRPV2 as a novel biomarker and therapeutic target in Leukemia-Implications concerning the resolution of pulmonary inflammation

(2019) Kodappully S. Siveen et al.   Scientific Reports

Pharmacological Inhibition of Porcupine, Disheveled and β-catenin in Wnt Signaling Pathway Ameliorates Diabetic Peripheral Neuropathy in Rats

(2019) Kahkashan Resham et al.   JOURNAL OF PAIN

Redox TRPs in diabetes and diabetic complications: Mechanisms and pharmacological modulation

(2019) Pratik Adhya et al.   PHARMACOLOGICAL RESEARCH

TRPV2 channel inhibitors attenuate fibroblast differentiation and contraction mediated by keratinocyte-derived TGF-β1 in an in vitro wound healing model of rats

(2018) Taro Ishii et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Determination of tranilast in bio-samples by LC–MS/MS: Application to a pharmacokinetic and brain tissue distribution study in rats

(2018) Wen Yang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Novel inhibitor candidates of TRPV2 prevent damage of dystrophic myocytes and ameliorate against dilated cardiomyopathy in a hamster model

(2018) Yuko Iwata et al.   Oncotarget

Oxidative stress and the amyloid beta peptide in Alzheimer’s disease

(2018) C. Cheignon et al.   Redox Biology

Neuroprotective Effect of Fisetin Against Amyloid-Beta-Induced Cognitive/Synaptic Dysfunction, Neuroinflammation, and Neurodegeneration in Adult Mice

(2016) Ashfaq Ahmad et al.   MOLECULAR NEUROBIOLOGY

CaMKII-Mediated CREB Phosphorylation Is Involved in Ca2+-Induced BDNF mRNA Transcription and Neurite Outgrowth Promoted by Electrical Stimulation

(2016) Xiaodong Yan et al.   PLoS One

Cognitive improvement of compound danshen in an Aβ25-35 peptide-induced rat model of Alzheimer’s disease

(2015) Min Liu et al.   BMC Complementary and Alternative Medicine

Genistein Inhibits Aβ25–35-Induced Synaptic Toxicity and Regulates CaMKII/CREB Pathway in SH-SY5Y Cells

(2015) Yuan-Di Xi et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Relationships Between Mitochondria and Neuroinflammation: Implications for Alzheimer's Disease

(2015) Heather M. Wilkins et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

GSK-3β, a pivotal kinase in Alzheimer disease

(2014) María Llorens-Marítin et al.   Frontiers in Molecular Neuroscience

Neurotoxicity of Amyloid  -Protein: Synaptic and Network Dysfunction

(2013) L. Mucke et al.   Cold Spring Harbor Perspectives in Medicine

Inhibition of the NFAT Pathway Alleviates Amyloid Beta Neurotoxicity in a Mouse Model of Alzheimer's Disease

(2012) E. Hudry et al.   JOURNAL OF NEUROSCIENCE

Time-Course and Regional Analyses of the Physiopathological Changes Induced after Cerebral Injection of an Amyloid β Fragment in Rats

(2011) Charleine Zussy et al.   AMERICAN JOURNAL OF PATHOLOGY

Dysregulated phosphorylation of Ca2+/calmodulin-dependent protein kinase II-α in the hippocampus of subjects with mild cognitive impairment and Alzheimer’s disease

(2011) Lindsay C. Reese et al.   JOURNAL OF NEUROCHEMISTRY

Downregulation of CREB expression in Alzheimer's brain and in Aβ-treated rat hippocampal neurons

(2011) Subbiah Pugazhenthi et al.   Molecular Neurodegeneration

Rapid Communication: Ca2+ Channel Blockers Attenuate β-Amyloid Peptide Toxicity to Cortical Neurons in Culture

(2010) John H. Weiss et al.   JOURNAL OF NEUROCHEMISTRY

Involvement of TRPV2 Activation in Intestinal Movement through Nitric Oxide Production in Mice

(2010) H. Mihara et al.   JOURNAL OF NEUROSCIENCE

TRPV2 Enhances Axon Outgrowth through Its Activation by Membrane Stretch in Developing Sensory and Motor Neurons

(2010) K. Shibasaki et al.   JOURNAL OF NEUROSCIENCE

Calcineurin dephosphorylates glycogen synthase kinase-3 beta at serine-9 in neuroblast-derived cells

(2009) Yeni Kim et al.   JOURNAL OF NEUROCHEMISTRY

Selective induction of calcineurin activity and signaling by oligomeric amyloid beta

(2008) Lindsay C. Reese et al.   AGING CELL