The Anticonvulsant Effect of a Novel Indole-Related Compound in the Kainate-Induced Status Epilepticus in Mice: The Role of the Antioxidant and Anti-inflammatory Mechanism

Evaluation of neurobiological and antioxidant effects of novel melatonin analogs in mice

(2020) Jana Tchekalarova et al.   SAUDI PHARMACEUTICAL JOURNAL

Analgesic activity of some aroylhydrazone-based molecular hybrids with antiseizure activity: in vivo and in silico evaluations

(2019) Stanislav Marchev et al.   BIOTECHNOLOGY & BIOTECHNOLOGICAL EQUIPMENT

Melatonin and Multiple Sclerosis: From Plausible Neuropharmacological Mechanisms of Action to Experimental and Clinical Evidence

(2019) Mahshid Yeganeh Salehpour et al.   CLINICAL DRUG INVESTIGATION

Discovery of novel indole-based aroylhydrazones as anticonvulsants: Pharmacophore-based design

(2019) Violina T. Angelova et al.   BIOORGANIC CHEMISTRY

Evaluation of the anticonvulsant effect of novel melatonin derivatives in the intravenous pentylenetetrazol seizure test in mice

(2019) Jana Tchekalarova et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

High mobility group box 1 enhances hyperthermia-induced seizures and secondary epilepsy associated with prolonged hyperthermia-induced seizures in developing rats

(2017) Masanori Ito et al.   METABOLIC BRAIN DISEASE

Therapeutic effects of anti-HMGB1 monoclonal antibody on pilocarpine-induced status epilepticus in mice

(2017) Li Fu et al.   Scientific Reports

The role of the melatoninergic system in epilepsy and comorbid psychiatric disorders

(2015) Jana Tchekalarova et al.   BRAIN RESEARCH BULLETIN

A definition and classification of status epilepticus - Report of the ILAE Task Force on Classification of Status Epilepticus

(2015) Eugen Trinka et al.   EPILEPSIA

HMGB1 Contributes to the Expression of P-Glycoprotein in Mouse Epileptic Brain through Toll-Like Receptor 4 and Receptor for Advanced Glycation End Products

(2015) Yan Chen et al.   PLoS One

Treatment with melatonin after status epilepticus attenuates seizure activity and neuronal damage but does not prevent the disturbance in diurnal rhythms and behavioral alterations in spontaneously hypertensive rats in kainate model of temporal lobe epilepsy

(2014) Zlatina Petkova et al.   EPILEPSY & BEHAVIOR

Prophylactic treatment with melatonin after status epilepticus: Effects on epileptogenesis, neuronal damage, and behavioral changes in a kainate model of temporal lobe epilepsy

(2013) Jana Tchekalarova et al.   EPILEPSY & BEHAVIOR

Melatonin in Alzheimer’s Disease

(2013) Li Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuroprotective effects of flavonoids extracted from licorice on kainate-induced seizure in mice through their antioxidant properties

(2013) Ling-hui Zeng et al.   Journal of Zhejiang University-SCIENCE B

Receptor for Advanced Glycation Endproducts is upregulated in temporal lobe epilepsy and contributes to experimental seizures

(2013) Valentina Iori et al.   NEUROBIOLOGY OF DISEASE

Strain-dependent effects of long-term treatment with melatonin on kainic acid-induced status epilepticus, oxidative stress and the expression of heat shock proteins

(2013) Milena Atanasova et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Therapeutic potential of melatonin and its analogs in Parkinson’s disease: focus on sleep and neuroprotection

(2011) Venkatramanujam Srinivasan et al.   Therapeutic Advances in Neurological Disorders

Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

(2010) Mattia Maroso et al.   NATURE MEDICINE