Ontogeny of ABC and SLC transporters in the microvessels of developing rat brain

The antiepileptic drug lamotrigine is a substrate of mouse and human breast cancer resistance protein (ABCG2)

(2015) Kerstin Römermann et al.   NEUROPHARMACOLOGY

Complete remission of childhood-onset epilepsy: stability and prediction over two decades

(2014) A. T. Berg et al.   BRAIN

MicroRNAs and their relevance to ABC transporters

(2014) Sierk Haenisch et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Lactate Transport and Signaling in the Brain: Potential Therapeutic Targets and Roles in Body—Brain Interaction

(2014) Linda Hildegard Bergersen   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

MDR-1 and MRP2 Gene Polymorphisms in Mexican Epileptic Pediatric Patients with Complex Partial Seizures

(2014) David Escalante-Santiago et al.   Frontiers in Neurology

Impact of P-glycoprotein and breast cancer resistance protein on the brain distribution of antiepileptic drugs in knockout mouse models

(2013) Haruka Nakanishi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

P-glycoprotein expression and function in patients with temporal lobe epilepsy: a case-control study

(2013) Maria Feldmann et al.   LANCET NEUROLOGY

In Vitro Blood-Brain Barrier Models Using Brain Capillary Endothelial Cells Isolated from Neonatal and Adult Rats Retain Age-Related Barrier Properties

(2013) Fuyuko Takata et al.   PLoS One

Blood-brain barrier dysfunction and epilepsy: Pathophysiologic role and therapeutic approaches

(2012) Nicola Marchi et al.   EPILEPSIA

IgG Leakage May Contribute to Neuronal Dysfunction in Drug-Refractory Epilepsies With Blood-Brain Barrier Disruption

(2012) Zuzanna Michalak et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

P-Glycoprotein, Breast Cancer Resistance Protein, Organic Anion Transporter 3, and Transporting Peptide 1a4 during Blood–Brain Barrier Maturation: Involvement of Wnt/β-Catenin and Endothelin-1 Signaling

(2012) Rania Harati et al.   MOLECULAR PHARMACEUTICS

A study of drug-resistant childhood epilepsy testing the new ILAE criteria

(2012) Julio Ramos-Lizana et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Barrier Mechanisms in the Developing Brain

(2012) Norman R. Saunders et al.   Frontiers in Pharmacology

Cerebral expression of drug transporters in epilepsy

(2011) Eleonora Aronica et al.   ADVANCED DRUG DELIVERY REVIEWS

Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328, -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cells

(2011) Xin Li et al.   BIOCHEMICAL PHARMACOLOGY

Refractory absence epilepsy associated with GLUT-1 deficiency syndrome

(2011) Susan Byrne et al.   EPILEPSIA

In vitro transport profile of carbamazepine, oxcarbazepine, eslicarbazepine acetate, and their active metabolites by human P-glycoprotein

(2011) Chunbo Zhang et al.   EPILEPSIA

Antiepileptic drugs modulate P-glycoproteins in the brain: A mice study with 11C-desmethylloperamide

(2011) Lieselotte Moerman et al.   EPILEPSY RESEARCH

Current concepts of blood-brain barrier development

(2011) Stefan Liebner et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Functional Maturation of Drug Transporters in the Developing, Neonatal, and Postnatal Kidney

(2011) D. E. Sweeney et al.   MOLECULAR PHARMACOLOGY

Altered expression of brain monocarboxylate transporter 1 in models of temporal lobe epilepsy

(2011) Fredrik Lauritzen et al.   NEUROBIOLOGY OF DISEASE

Control of MCT1 function in cerebrovascular endothelial cells by intracellular pH

(2010) Amy L. Uhernik et al.   BRAIN RESEARCH

hsa-miR-520h downregulates ABCG2 in pancreatic cancer cells to inhibit migration, invasion and side populations

(2010) F Wang et al.   BRITISH JOURNAL OF CANCER

Comparison of in vitro cell models in predicting in vivo brain entry of drugs

(2010) Jenni J. Hakkarainen et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Monocarboxylate transporter 1 is deficient on microvessels in the human epileptogenic hippocampus

(2010) Fredrik Lauritzen et al.   NEUROBIOLOGY OF DISEASE

Efflux mechanisms at the developing brain barriers: ABC-transporters in the fetal and postnatal rat

(2010) C. Joakim Ek et al.   TOXICOLOGY LETTERS

Newborn- and Adult-Derived Brain Microvascular Endothelial Cells Show Age-Related Differences in Phenotype and Glutamate-Evoked Protease Release

(2009) Hélène Legros et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Comparative gene expression profiles of ABC transporters in brain microvessel endothelial cells and brain in five species including human

(2009) Mark S. Warren et al.   PHARMACOLOGICAL RESEARCH

Tissue Distribution, Gender-Divergent Expression, Ontogeny, and Chemical Induction of Multidrug Resistance Transporter Genes (Mdr1a, Mdr1b, Mdr2) in Mice

(2008) Y. J. Cui et al.   DRUG METABOLISM AND DISPOSITION

Transport of valproate at intestinal epithelial (Caco-2) and brain endothelial (RBE4) cells: Mechanism and substrate specificity

(2008) Wiebke Fischer et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

The ketogenic diet for the treatment of childhood epilepsy: a randomised controlled trial

(2008) Elizabeth G Neal et al.   LANCET NEUROLOGY

A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes

(2008) Shinsuke Nakagawa et al.   NEUROCHEMISTRY INTERNATIONAL

Several major antiepileptic drugs are substrates for human P-glycoprotein

(2008) Carlos Luna-Tortós et al.   NEUROPHARMACOLOGY

The ontogeny of drug metabolizing enzymes and transporters in the rat

(2008) Loeckie de Zwart et al.   REPRODUCTIVE TOXICOLOGY