The memory of neuronal mitochondrial stress is inherited transgenerationally via elevated mitochondrial DNA levels

Mitohormesis in Hypothalamic POMC Neurons Mediates Regular Exercise-Induced High-Turnover Metabolism

(2021) Gil Myoung Kang et al.   Cell Metabolism

TBtools: An Integrative Toolkit Developed for Interactive Analyses of Big Biological Data

(2020) Chengjie Chen et al.   Molecular Plant

NuRD mediates mitochondrial stress–induced longevity via chromatin remodeling in response to acetyl-CoA level

(2020) Di Zhu et al.   Science Advances

Nongenetic inheritance and multigenerational plasticity in the nematode C. elegans

(2020) L Ryan Baugh et al.   eLife

Piwi/PRG-1 Argonaute and TGF-β Mediate Transgenerational Learned Pathogenic Avoidance

(2019) Rebecca S. Moore et al.   CELL

Neuronal Small RNAs Control Behavior Transgenerationally

(2019) Rachel Posner et al.   CELL

Insulin/IGF Signaling and Vitellogenin Provisioning Mediate Intergenerational Adaptation to Nutrient Stress

(2019) James M. Jordan et al.   CURRENT BIOLOGY

Translational Regulation of Non-autonomous Mitochondrial Stress Response Promotes Longevity

(2019) Jianfeng Lan et al.   Cell Reports

Mitochondrial fusion is required for regulation of mitochondrial DNA replication

(2019) Eduardo Silva Ramos et al.   PLoS Genetics

A Futile Battle? Protein Quality Control and the Stress of Aging

(2018) Ryo Higuchi-Sanabria et al.   DEVELOPMENTAL CELL

The Mitochondrial Unfolded Protein Response Is Mediated Cell-Non-autonomously by Retromer-Dependent Wnt Signaling

(2018) Qian Zhang et al.   CELL

Transgenerational Effects of Extended Dauer Diapause on Starvation Survival and Gene Expression Plasticity inCaenorhabditis elegans

(2018) Amy K. Webster et al.   GENETICS

N6-methyldeoxyadenine is a transgenerational epigenetic signal for mitochondrial stress adaptation

(2018) Chengchuan Ma et al.   NATURE CELL BIOLOGY

Intergenerational and transgenerational epigenetic inheritance in animals

(2018) Marcos Francisco Perez et al.   NATURE CELL BIOLOGY

Functions and mechanisms of epigenetic inheritance in animals

(2018) Ksenia Skvortsova et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Maintenance of Proteostasis by P Body-Mediated Regulation of eIF4E Availability during Aging in Caenorhabditis elegans

(2018) Matthias Rieckher et al.   Cell Reports

Maternal age generates phenotypic variation in Caenorhabditis elegans

(2017) Marcos Francisco Perez et al.   NATURE

The mitochondrial UPR: mechanisms, physiological functions and implications in ageing

(2017) Tomer Shpilka et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transgenerational transmission of environmental information in C. elegans

(2017) Adam Klosin et al.   SCIENCE

Duplication of the mitochondrial control region is associated with increased longevity in birds

(2016) Ilze Skujina et al.   Aging-US

Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity

(2016) Carsten Merkwirth et al.   CELL

Mitochondrial Stress Induces Chromatin Reorganization to Promote Longevity and UPR mt

(2016) Ye Tian et al.   CELL

Neuroendocrine Coordination of Mitochondrial Stress Signaling and Proteostasis

(2016) Kristen M. Berendzen et al.   CELL

Neuropeptide signals cell non-autonomous mitochondrial unfolded protein response

(2016) Li-Wa Shao et al.   CELL RESEARCH

Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing

(2016) Ana Latorre-Pellicer et al.   NATURE

Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response

(2016) Yi-Fan Lin et al.   NATURE

Maternal Diet and Insulin-Like Signaling Control Intergenerational Plasticity of Progeny Size and Starvation Resistance

(2016) Jonathan D. Hibshman et al.   PLoS Genetics

Age-Related and Heteroplasmy-Related Variation in Human mtDNA Copy Number

(2016) Manja Wachsmuth et al.   PLoS Genetics

Transgenerational Effects of Early Life Starvation on Growth, Reproduction, and Stress Resistance in Caenorhabditis elegans

(2015) M. A. Jobson et al.   GENETICS

Mitochondrial and Nuclear Accumulation of the Transcription Factor ATFS-1 Promotes OXPHOS Recovery during the UPRmt

(2015) Amrita M. Nargund et al.   MOLECULAR CELL

Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder

(2015) Q. Chen et al.   SCIENCE

Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools

(2015) Jun Ding et al.   PLoS Genetics

Paternal Diet Defines Offspring Chromatin State and Intergenerational Obesity

(2014) Anita Öst et al.   CELL

Starvation-Induced Transgenerational Inheritance of Small RNAs in C. elegans

(2014) Oded Rechavi et al.   CELL

Mitochondrial DNA copy number in peripheral blood cells declines with age and is associated with general health among elderly

(2014) Jonas Mengel-From et al.   HUMAN GENETICS

Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection

(2014) Mark W. Pellegrino et al.   NATURE

XBP-1 Is a Cell-Nonautonomous Regulator of Stress Resistance and Longevity

(2013) Rebecca C. Taylor et al.   CELL

Muscle Mitohormesis Promotes Longevity via Systemic Repression of Insulin Signaling

(2013) Edward Owusu-Ansah et al.   CELL

Mitonuclear protein imbalance as a conserved longevity mechanism

(2013) Riekelt H. Houtkooper et al.   NATURE

Parental olfactory experience influences behavior and neural structure in subsequent generations

(2013) Brian G Dias et al.   NATURE NEUROSCIENCE

Chromosome-scale selective sweeps shape Caenorhabditis elegans genomic diversity

(2012) Erik C Andersen et al.   NATURE GENETICS

Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation

(2012) A. M. Nargund et al.   SCIENCE

The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity

(2011) Jenni Durieux et al.   CELL

FGF-21 as a biomarker for muscle-manifesting mitochondrial respiratory chain deficiencies: a diagnostic study

(2011) Anu Suomalainen et al.   LANCET NEUROLOGY

Blue native electrophoresis to study mitochondrial complex I in C. elegans

(2010) Daniela van den Ecker et al.   ANALYTICAL BIOCHEMISTRY

Copy number variation in the genomes of twelve natural isolates of Caenorhabditis elegans

(2010) Jason S Maydan et al.   BMC GENOMICS

The Matrix Peptide Exporter HAF-1 Signals a Mitochondrial UPR by Activating the Transcription Factor ZC376.7 in C. elegans

(2010) Cole M. Haynes et al.   MOLECULAR CELL

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Mitochondrial DNA level, but not active replicase, is essential for Caenorhabditis elegans development

(2009) Ivana Bratic et al.   NUCLEIC ACIDS RESEARCH