Human melanocyte development and melanoma dedifferentiation at single-cell resolution

Cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Deciphering the functional heterogeneity of skin fibroblasts using single‐cell RNA sequencing

(2020) Vera Vorstandlechner et al.   FASEB JOURNAL

Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis

(2020) Kerrie L. Marie et al.   Nature Communications

Single-Cell Transcriptomic Comparison of Human Fetal Retina, hPSC-Derived Retinal Organoids, and Long-Term Retinal Cultures

(2020) Akshayalakshmi Sridhar et al.   Cell Reports

Hair follicle stem cells regulate retinoid metabolism to maintain the self-renewal niche for melanocyte stem cells

(2020) Zhiwei Lu et al.   eLife

Characterizing and inferring quantitative cell cycle phase in single-cell RNA-seq data analysis

(2020) Chiaowen Joyce Hsiao et al.   GENOME RESEARCH

Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming

(2020) Llorenç Solé-Boldo et al.   Communications Biology

The Gene Ontology resource: enriching a GOld mine

(2020) et al.   NUCLEIC ACIDS RESEARCH

A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia

(2019) Kaustubh Adhikari et al.   Nature Communications

An Updated Classification of Hair Follicle Morphogenesis

(2019) Nivedita Saxena et al.   EXPERIMENTAL DERMATOLOGY

Tropomyosin-Related Kinase Receptor and Neurotrophin Expression in Cutaneous Melanoma Is Associated with a Poor Prognosis and Decreased Survival

(2019) Luís Carlos Moreira Antunes et al.   ONCOLOGY

CD34 defines melanocyte stem cell subpopulations with distinct regenerative properties

(2019) Sandeep S. Joshi et al.   PLoS Genetics

Defining Transcriptional Signatures of Human Hair Follicle Cell States

(2019) Rie Takahashi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Decoding human fetal liver haematopoiesis

(2019) Dorin-Mirel Popescu et al.   NATURE

Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain

(2019) Zhongqiu Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ca2+ transients in melanocyte dendrites and dendritic spine-like structures evoked by cell-to-cell signaling

(2019) Rachel L. Belote et al.   JOURNAL OF CELL BIOLOGY

Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress

(2018) Jennifer Tsoi et al.   CANCER CELL

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

(2018) Jianfang Liu et al.   CELL

Toward Minimal Residual Disease-Directed Therapy in Melanoma

(2018) Florian Rambow et al.   CELL

Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

(2018) Tathiane M. Malta et al.   CELL

Tracing the temporal-spatial transcriptome landscapes of the human fetal digestive tract using single-cell RNA-sequencing

(2018) Shuai Gao et al.   NATURE CELL BIOLOGY

PRAME Expression in Melanocytic Tumors

(2018) Cecilia Lezcano et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

(2018) Livnat Jerby-Arnon et al.   CELL

Melanoma subtypes: Genomic profiles, prognostic molecular markers and therapeutic possibilities

(2018) Roy Rabbie et al.   JOURNAL OF PATHOLOGY

A curated gene list for expanding the horizons of pigmentation biology

(2018) Laura L. Baxter et al.   Pigment Cell & Melanoma Research

Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution

(2018) Jeffrey B. Cheng et al.   Cell Reports

Integrated genomic analyses reveal frequent TERT aberrations in acral melanoma

(2017) Winnie S. Liang et al.   GENOME RESEARCH

Malignant Melanoma in African–Americans

(2017) Krishnaraj Mahendraraj et al.   MEDICINE

Whole-genome landscapes of major melanoma subtypes

(2017) Nicholas K. Hayward et al.   NATURE

DrugBank 5.0: a major update to the DrugBank database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

Loci associated with skin pigmentation identified in African populations

(2017) Nicholas G. Crawford et al.   SCIENCE

Intratumor and Intertumor Heterogeneity in Melanoma

(2017) Tomasz M. Grzywa et al.   Translational Oncology

The Human Penis Is a Genuine Immunological Effector Site

(2017) Alexis Sennepin et al.   Frontiers in Immunology

ZEB1‐mediated melanoma cell plasticity enhances resistance to MAPK inhibitors

(2016) Geoffrey Richard et al.   EMBO Molecular Medicine

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

(2016) I. Tirosh et al.   SCIENCE

Signaling Networks among Stem Cell Precursors, Transit-Amplifying Progenitors, and their Niche in Developing Hair Follicles

(2016) Amélie Rezza et al.   Cell Reports

Genomic Classification of Cutaneous Melanoma

(2015) Rehan Akbani et al.   CELL

The melanocyte lineage in development and disease

(2015) R. L. Mort et al.   DEVELOPMENT

An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin

(2015) Rachel Sennett et al.   DEVELOPMENTAL CELL

Site-specific migration of human fetal melanocytes in volar skin

(2015) Motoki Nakamura et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

A survey of human brain transcriptome diversity at the single cell level

(2015) Spyros Darmanis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular stratification of metastatic melanoma using gene expression profiling : Prediction of survival outcome and benefit from molecular targeted therapy

(2015) Helena Cirenajwis et al.   Oncotarget

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression

(2014) G Denecker et al.   CELL DEATH AND DIFFERENTIATION

A melanocyte-melanoma precursor niche in sweat glands of volar skin

(2014) Natsuko Okamoto et al.   Pigment Cell & Melanoma Research

Wnt5A promotes an adaptive, senescent-like stress response, while continuing to drive invasion in melanoma cells

(2014) Marie R. Webster et al.   Pigment Cell & Melanoma Research

Id2, Id3 and Id4 overcome a Smad7-mediated block in tumorigenesis, generating TGF- -independent melanoma

(2013) K. A. DiVito et al.   CARCINOGENESIS

Transcriptome Profiling Identifies HMGA2 as a Biomarker of Melanoma Progression and Prognosis

(2013) Leon Raskin et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Smart-seq2 for sensitive full-length transcriptome profiling in single cells

(2013) Simone Picelli et al.   NATURE METHODS

Neural crest and Schwann cell progenitor-derived melanocytes are two spatially segregated populations similarly regulated by Foxd3

(2013) E. Nitzan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling Neural Crest Induction, Melanocyte Specification, and Disease-Related Pigmentation Defects in hESCs and Patient-Specific iPSCs

(2013) Yvonne Mica et al.   Cell Reports

A Simple Assay Method for Melanosome Transfer

(2012) Hye Ryung Choi et al.   Annals of Dermatology

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation

(2012) Jennifer Landsberg et al.   NATURE

Systematic classification of melanoma cells by phenotype-specific gene expression mapping

(2012) Daniel S. Widmer et al.   Pigment Cell & Melanoma Research

Transcription Factor TCF4 Maintains the Properties of Human Corneal Epithelial Stem Cells

(2012) Rong Lu et al.   STEM CELLS

On the Development of Neurocutaneous Units—Implications for the Histogenesis of Congenital, Acquired, and Dysplastic Nevi

(2011) Stewart F Cramer et al.   AMERICAN JOURNAL OF DERMATOPATHOLOGY

Acral Lentiginous Melanoma

(2009) Porcia T. Bradford et al.   ARCHIVES OF DERMATOLOGY

Schwann Cell Precursors from Nerve Innervation Are a Cellular Origin of Melanocytes in Skin

(2009) Igor Adameyko et al.   CELL

In vivo Switching of Human Melanoma Cells between Proliferative and Invasive States

(2008) K. S. Hoek et al.   CANCER RESEARCH

Expression patterns of MITF during human cutaneous embryogenesis: evidence for bulge epithelial expression and persistence of dermal melanoblasts

(2008) Briana C. Gleason et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Stem cell factor/c-Kit signalling in normal and androgenetic alopecia hair follicles

(2008) Valerie A Randall et al.   JOURNAL OF ENDOCRINOLOGY

A Genome-Wide Association Study Identifies Novel Alleles Associated with Hair Color and Skin Pigmentation

(2008) Jiali Han et al.   PLoS Genetics