Optimization of PEGylated KL4 Peptide for siRNA Delivery with Improved Pulmonary Tolerance
出版年份 2021 全文链接
标题
Optimization of PEGylated KL4 Peptide for siRNA Delivery with Improved Pulmonary Tolerance
作者
关键词
-
出版物
MOLECULAR PHARMACEUTICS
Volume 18, Issue 6, Pages 2218-2232
出版商
American Chemical Society (ACS)
发表日期
2021-05-21
DOI
10.1021/acs.molpharmaceut.0c01242
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Givosiran: First Approval
- (2020) Lesley J. Scott DRUGS
- Modification of KL4 Peptide Revealed the Importance of Alpha-Helical Structure for Efficient Small Interfering RNA Delivery
- (2020) Yingshan Qiu et al. Nucleic Acid Therapeutics
- Inhaled RNA Therapy: From Promise to Reality
- (2020) Michael Y.T. Chow et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Intratumoral delivery and therapeutic efficacy of nanoparticle-encapsulated anti-tumor siRNA following intrapulmonary administration for potential treatment of lung cancer
- (2019) Yukimune Kanehira et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- Effective mRNA pulmonary delivery by dry powder formulation of PEGylated synthetic KL4 peptide
- (2019) Yingshan Qiu et al. JOURNAL OF CONTROLLED RELEASE
- Leading RNA Interference Therapeutics Part 2: Silencing Delta-Aminolevulinic Acid Synthase 1, with a Focus on Givosiran
- (2019) Pedro Renato de Paula Brandão et al. Molecular Diagnosis & Therapy
- Oligonucleotides to the (Gene) Rescue: FDA Approvals 2017–2019
- (2019) Jacqueline Rüger et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Lipid nanoparticles with minimum burst release of TNF-α siRNA show strong activity against rheumatoid arthritis unresponsive to methotrexate
- (2018) Abdulaziz M. Aldayel et al. JOURNAL OF CONTROLLED RELEASE
- Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis
- (2018) David Adams et al. NEW ENGLAND JOURNAL OF MEDICINE
- Monodisperse engineered PEGs for bio-related applications
- (2018) Kazushi Kinbara POLYMER JOURNAL
- Intratracheal administration of siRNA dry powder targeting vascular endothelial growth factor inhibits lung tumor growth in mice
- (2018) Kei Miwata et al. Molecular Therapy-Nucleic Acids
- Surfactant protein B (SP-B) enhances the cellular siRNA delivery of proteolipid coated nanogels for inhalation therapy
- (2018) Pieterjan Merckx et al. Acta Biomaterialia
- PEGylation rate influences peptide-based nanoparticles mediated siRNA delivery in vitro and in vivo
- (2017) Gudrun Aldrian et al. JOURNAL OF CONTROLLED RELEASE
- PEGylation of the GALA Peptide Enhances the Lung-Targeting Activity of Nanocarriers That Contain Encapsulated siRNA
- (2017) Sarochin Santiwarangkool et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Structure-based antigenic epitope and PEGylation improve the efficacy of staphylokinase
- (2017) Yanying Xu et al. Microbial Cell Factories
- From Pulmonary Surfactant, Synthetic KL4 Peptide as Effective siRNA Delivery Vector for Pulmonary Delivery
- (2017) Yingshan Qiu et al. MOLECULAR PHARMACEUTICS
- Combinatorial treatment of idiopathic pulmonary fibrosis using nanoparticles with prostaglandin E and siRNA(s)
- (2017) Olga. B. Garbuzenko et al. Nanomedicine-Nanotechnology Biology and Medicine
- The impact of microfluidic mixing of triblock micelleplexes on in vitro $/$ in vivo gene silencing and intracellular trafficking
- (2017) Daniel P Feldmann et al. NANOTECHNOLOGY
- A Supramolecular Vaccine Platform Based on α-Helical Peptide Nanofibers
- (2017) Yaoying Wu et al. ACS Biomaterials-Science & Engineering
- A Supramolecular Vaccine Platform Based on α-Helical Peptide Nanofibers
- (2017) Yaoying Wu et al. ACS Biomaterials Science & Engineering
- Effect of Electrolyte Concentration on the Stern Layer Thickness at a Charged Interface
- (2016) Matthew A. Brown et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Insight into the relationship between the cell culture model, cell trafficking and siRNA silencing efficiency
- (2016) Victoria Capel et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Combinatorial Optimization of Sequence-Defined Oligo(ethanamino)amides for Folate Receptor-Targeted pDNA and siRNA Delivery
- (2016) Dongsheng He et al. BIOCONJUGATE CHEMISTRY
- How PEGylation influences protein conformational stability
- (2016) Paul B Lawrence et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- PEGylation of lipoplexes: The right balance between cytotoxicity and siRNA effectiveness
- (2016) Anna Lechanteur et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Polyethylene glycol (PEG): a versatile polymer for pharmaceutical applications
- (2016) Anisha A. D’souza et al. Expert Opinion on Drug Delivery
- PEGylation of paclitaxel largely improves its safety and anti-tumor efficacy following pulmonary delivery in a mouse model of lung carcinoma
- (2016) Tian Luo et al. JOURNAL OF CONTROLLED RELEASE
- Heat Shock Protein 27 Plays a Pivotal Role in Myofibroblast Differentiation and in the Development of Bleomycin-Induced Pulmonary Fibrosis
- (2016) Ah-Mee Park et al. PLoS One
- Inhalable Dry Powder Formulations of siRNA and pH-Responsive Peptides with Antiviral Activity Against H1N1 Influenza Virus
- (2015) Wanling Liang et al. MOLECULAR PHARMACEUTICS
- RNAi-based glyconanoparticles trigger apoptotic pathways for in vitro and in vivo enhanced cancer-cell killing
- (2015) João Conde et al. Nanoscale
- Chemically defined polyethylene glycol siRNA conjugates with enhanced gene silencing effect
- (2014) Zuzana Gaziova et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Native chemical ligation for conversion of sequence-defined oligomers into targeted pDNA and siRNA carriers
- (2014) Can Yang Zhang et al. JOURNAL OF CONTROLLED RELEASE
- Efficient delivery of RNA interference oligonucleotides to polarized airway epithelia in vitro
- (2013) Shyam Ramachandran et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Self-Assembling Multidomain Peptide Fibers with Aromatic Cores
- (2013) Erica L. Bakota et al. BIOMACROMOLECULES
- Development and characterization of chitosan-PEG-TAT nanoparticles for the intracellular delivery of siRNA
- (2013) Satya Prakash et al. International Journal of Nanomedicine
- Growth of human bronchial epithelial cells at an air-liquid interface alters the response to particle exposure
- (2013) Andrew J Ghio et al. Particle and Fibre Toxicology
- Cationic and PEGylated Amphiphilic Cyclodextrins: Co-Formulation Opportunities for Neuronal Sirna Delivery
- (2013) Aoife M. O’Mahony et al. PLoS One
- PEGylation is effective in reducing immunogenicity, immunotoxicity, and hepatotoxicity of α-momorcharinin vivo
- (2012) Jue-cun Zheng et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Defined Folate-PEG-siRNA Conjugates for Receptor-specific Gene Silencing
- (2012) Christian Dohmen et al. Molecular Therapy-Nucleic Acids
- Effects of PEG size on structure, function and stability of PEGylated BSA
- (2011) Bitten Plesner et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Biophysical characterisation of GlycoPEGylated recombinant human factor VIIa
- (2011) Bitten Plesner et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Prevention of benzyl alcohol-induced aggregation of chymotrypsinogen by PEGylation
- (2011) José A. Rodríguez-Martínez et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Enzymatic activity and thermal stability of PEG-α-chymotrypsin conjugates
- (2009) José A. Rodríguez-Martínez et al. BIOTECHNOLOGY LETTERS
- Monocyte Chemoattractant Protein-1 (MCP-1): An Overview
- (2009) Satish L. Deshmane et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Nonviral siRNA Delivery to the Lung: Investigation of PEG−PEI Polyplexes and Their In Vivo Performance
- (2009) Olivia M. Merkel et al. MOLECULAR PHARMACEUTICS
- The Impact of PEGylation on Biological Therapies
- (2008) Francesco M Veronese et al. BIODRUGS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now