Analytical and Computational Methods for the Determination of Drug-Polymer Solubility and Miscibility
出版年份 2021 全文链接
标题
Analytical and Computational Methods for the Determination of Drug-Polymer Solubility and Miscibility
作者
关键词
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出版物
MOLECULAR PHARMACEUTICS
Volume 18, Issue 8, Pages 2835-2866
出版商
American Chemical Society (ACS)
发表日期
2021-05-27
DOI
10.1021/acs.molpharmaceut.1c00141
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Molecular Simulation and Statistical Learning Methods toward Predicting Drug–Polymer Amorphous Solid Dispersion Miscibility, Stability, and Formulation Design
- (2021) Daniel M. Walden et al. MOLECULES
- Correlation between drug dissolution and resistance to water-induced phase separation in solid dispersion formulations revealed by solid-state NMR spectroscopy
- (2020) Hitomi Okada et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Spray-Dried Amorphous Solid Dispersions of Griseofulvin in HPC/Soluplus/SDS: Elucidating the Multifaceted Impact of SDS as a Minor Component
- (2020) Mahbubur Rahman et al. Pharmaceutics
- Controlled-Release from High-Loaded Reservoir-Type Systems—A Case Study of Ethylene-Vinyl Acetate and Progesterone
- (2020) Ioannis Koutsamanis et al. Pharmaceutics
- Crystallization tendency of APIs possessing different thermal and glass related properties in amorphous solid dispersions
- (2020) Afroditi Kapourani et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Ketoprofen poly(lactide-co-glycolide) physical interaction studied by Brillouin spectroscopy and molecular dynamics simulations
- (2020) Paolo Blasi et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Atomic-Level Drug Substance and Polymer Interaction in Posaconazole Amorphous Solid Dispersion from Solid-State NMR
- (2020) Xingyu Lu et al. MOLECULAR PHARMACEUTICS
- NMR and Thermal Studies for the Characterization of Mass Transport and Phase Separation in Paracetamol/Copovidone Hot-Melt Extrusion Formulations
- (2020) Elena Pisa et al. MOLECULAR PHARMACEUTICS
- Synergistic and antagonistic effects of various amphiphilic polymer combinations in enhancing griseofulvin release from ternary amorphous solid dispersions
- (2020) Mahbubur Rahman et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Thermodynamic aspects of the preparation of amorphous solid dispersions of Naringenin with enhanced dissolution rate
- (2020) Durgesh K. Jha et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- The design and development of high drug loading amorphous solid dispersion for hot-melt extrusion platform
- (2020) Yiwei Tian et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Amorphous solid dispersions: An update for preparation, characterization, mechanism on bioavailability, stability, regulatory considerations and marketed products
- (2020) Palpandi Pandi et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Experimental, Thermodynamic, and Molecular Modeling Evaluation of Amorphous Simvastatin-Poly(vinylpyrrolidone) Solid Dispersions
- (2020) Afroditi Kapourani et al. MOLECULAR PHARMACEUTICS
- In Vitro and In Vivo Behaviors of KinetiSol and Spray-Dried Amorphous Solid Dispersions of a Weakly Basic Drug and Ionic Polymer
- (2020) Scott V. Jermain et al. MOLECULAR PHARMACEUTICS
- Investigating Various Parametrization Strategies for Pharmaceuticals within the PC-SAFT Equation of State
- (2020) Martin Klajmon JOURNAL OF CHEMICAL AND ENGINEERING DATA
- Characterization of the Solid Physical State of API and Its Distribution in Pharmaceutical Hot Melt Extrudates Using Terahertz Raman Imaging
- (2019) Mohammed Ibrahim et al. AAPS PHARMSCITECH
- Homogeneity of Amorphous Solid Dispersions – An Example with KinetiSol®
- (2019) Scott V. Jermain et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Interactions Between Paracetamol and Hypromellose in the Solid State
- (2019) Edyta Leyk et al. Frontiers in Pharmacology
- Influence of glass forming ability on the physical stability of supersaturated amorphous solid dispersions
- (2019) Lasse Ingerslev Blaabjerg et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Broadband dielectric spectroscopy as an experimental alternative to calorimetric determination of the solubility of drugs into polymer matrix: Case of flutamide and various polymeric matrixes
- (2019) K. Chmiel et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Molecular modelling and simulation of fusion-based amorphous drug dispersions in polymer/plasticizer blends
- (2019) Panagiotis Barmpalexis et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Crystal growth of celecoxib from amorphous state – polymorphism, growth mechanism, and kinetics
- (2019) Kunlin Wang et al. CRYSTAL GROWTH & DESIGN
- Drug–polymer miscibility, interactions, and precipitation inhibition studies for the development of amorphous solid dispersions for the poorly soluble anticancer drug flutamide
- (2019) Anne Trivino et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Molecular Interactions in Posaconazole Amorphous Solid Dispersions from Two-Dimensional Solid-State NMR Spectroscopy
- (2019) Xingyu Lu et al. MOLECULAR PHARMACEUTICS
- Are traditional small-scale screening methods reliable to predict pharmaceutical spray drying?
- (2019) Sadegh Poozesh et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- Analytical and Computational Methods for the Estimation of Drug-Polymer Solubility and Miscibility in Solid Dispersions Development
- (2019) Djordje Medarević et al. Pharmaceutics
- Determination of drug-polymer solubility from supersaturated spray-dried amorphous solid dispersions: A case study with Efavirenz and Soluplus®
- (2019) B.L.A. Costa et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Effect of Variability of Physical Properties of Povidone K30 on Crystallization and Drug–Polymer Miscibility of Celecoxib–Povidone K30 Amorphous Solid Dispersions
- (2019) Chaitali Phadke et al. MOLECULAR PHARMACEUTICS
- Use of Terahertz-Raman Spectroscopy to Determine Solubility of the Crystalline Active Pharmaceutical Ingredient in Polymeric Matrices during Hot Melt Extrusion
- (2019) Ecaterina Bordos et al. MOLECULAR PHARMACEUTICS
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- (2019) Yiwei Tian et al. Pharmaceutics
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- (2019) Moshe Honick et al. AAPS PHARMSCITECH
- How does the high pressure affects the solubility of the drug within the polymer matrix in solid dispersion systems
- (2019) K. Chmiel et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
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- (2019) M. Latreche et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
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- (2019) Chenyang Shi et al. MOLECULAR PHARMACEUTICS
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- (2019) Marta F. Simões et al. MOLECULAR PHARMACEUTICS
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- (2019) Luis Almeida e Sousa et al. PHARMACEUTICAL RESEARCH
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- (2019) Piyush Panini et al. Pharmaceutics
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- (2019) Georgia Tsakiridou et al. Pharmaceutics
- Investigation of drug-polymer miscibility, biorelevant dissolution, and bioavailability improvement of Dolutegravir-polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer solid dispersions
- (2019) Dani Lakshman et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
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- (2019) Mahbubur Rahman et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Amorphous solid dispersion of ibuprofen: A comparative study on the effect of solution based techniques
- (2019) Ahmad Ziaee et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- In situ solid-state NMR characterization of pharmaceutical materials: An example of drug-polymer thermal mixing
- (2019) Jinglin Yin et al. MAGNETIC RESONANCE IN CHEMISTRY
- Molecular simulations for amorphous drug formulation: Polymeric matrix properties relevant to hot-melt extrusion
- (2018) Panagiotis Barmpalexis et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Rheological analysis of itraconazole-polymer mixtures to determine optimal melt extrusion temperature for development of amorphous solid dispersion
- (2018) Nayan Solanki et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Physical stability of API/polymer-blend amorphous solid dispersions
- (2018) Kristin Lehmkemper et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Investigating phase separation in amorphous solid dispersions via Raman mapping
- (2018) Christian Luebbert et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Comparison of two DSC-based methods to predict drug-polymer solubility
- (2018) Malte Bille Rask et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Predicting physical stability of ternary amorphous solid dispersions using specific mechanical energy in a hot melt extrusion process
- (2018) Masataka Hanada et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Isoniazid-loaded orodispersible strips: Methodical design, optimization and in vitro-in silico characterization
- (2018) Oluwatoyin A. Adeleke et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Tailoring supersaturation from amorphous solid dispersions
- (2018) Na Li et al. JOURNAL OF CONTROLLED RELEASE
- The Synergetic Effects of Nonpolar and Polar Protic Solvents on the Properties of Felodipine and Soluplus in Solutions, Casting Films, and Spray-Dried Solid Dispersions
- (2018) Yuqi Chen et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Predicting Solubility/Miscibility in Amorphous Dispersions: It Is Time to Move Beyond Regular Solution Theories
- (2018) Bradley D. Anderson JOURNAL OF PHARMACEUTICAL SCIENCES
- The Application of Modeling and Prediction to the Formation and Stability of Amorphous Solid Dispersions
- (2018) Kevin DeBoyace et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Enhanced Biopharmaceutical Performance of Rivaroxaban through Polymeric Amorphous Solid Dispersion
- (2018) Sunita Metre et al. MOLECULAR PHARMACEUTICS
- Qualitative and Quantitative Characterization of Composition Heterogeneity on the Surface of Spray Dried Amorphous Solid Dispersion Particles by an Advanced Surface Analysis Platform with High Surface Sensitivity and Superior Spatial Resolution
- (2018) Sonal V. Bhujbal et al. MOLECULAR PHARMACEUTICS
- The Development of Quasi-isothermal Calorimetry for the Measurement of Drug–Polymer Miscibility and Crystallization Kinetics: Olanzapine-Loaded PLGA Microparticles
- (2018) Sean Askin et al. MOLECULAR PHARMACEUTICS
- Phase Behavior of Drug-Hydroxypropyl Methylcellulose Amorphous Solid Dispersions Produced from Various Solvent Systems: Mechanistic Understanding of the Role of Polymer using Experimental and Theoretical Methods
- (2018) Naila A. Mugheirbi et al. MOLECULAR PHARMACEUTICS
- Solid-State NMR Investigation of Drug-Excipient Interactions and Phase Behavior in Indomethacin-Eudragit E Amorphous Solid Dispersions
- (2018) Joseph W. Lubach et al. PHARMACEUTICAL RESEARCH
- Synergistic Effect of Polyvinyl Alcohol and Copovidone in Itraconazole Amorphous Solid Dispersions
- (2018) Kamil Wlodarski et al. PHARMACEUTICAL RESEARCH
- Impact of Drug-Polymer Miscibility on Enthalpy Relaxation of Irbesartan Amorphous Solid Dispersions
- (2018) Sonu Dalsania et al. PHARMACEUTICAL RESEARCH
- Physical Stability of Amorphous Solid Dispersions: a Physicochemical Perspective with Thermodynamic, Kinetic and Environmental Aspects
- (2018) Xia Lin et al. PHARMACEUTICAL RESEARCH
- A novel approach for measuring room temperature enthalpy of mixing and associated solubility estimation of a drug in a polymer matrix
- (2018) Jonas Alin et al. POLYMER
- Study the influence of formulation process parameters on solubility and dissolution enhancement of efavirenz solid solutions prepared by hot-melt extrusion: a QbD methodology
- (2018) Jaywant Pawar et al. Drug Delivery and Translational Research
- Orally Disintegrating Tablets Containing Melt Extruded Amorphous Solid Dispersion of Tacrolimus for Dissolution Enhancement
- (2018) Poovizhi Ponnammal et al. Pharmaceutics
- Prediction of Phase Behavior of Spray-Dried Amorphous Solid Dispersions: Assessment of Thermodynamic Models, Standard Screening Methods and a Novel Atomization Screening Device with Regard to Prediction Accuracy
- (2018) Aymeric Ousset et al. Pharmaceutics
- Lacidipine Amorphous Solid Dispersion Based on Hot Melt Extrusion: Good Miscibility, Enhanced Dissolution, and Favorable Stability
- (2018) Long Xi et al. AAPS PHARMSCITECH
- Investigation of miscibility estimation methods between indomethacin and poly(vinylpyrrolidone-co-vinyl acetate)
- (2018) Romina Pezzoli et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Development of Solid Dispersion by Hot Melt Extrusion Using Mixtures of Polyoxylglycerides with Polymers as Carriers for Increasing Dissolution Rate of a Model Poorly Soluble Drug
- (2018) Jaydip Vasoya et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- 1H NMR relaxation study to evaluate the crystalline state of active pharmaceutical ingredients containing solid dosage forms using time domain NMR
- (2018) Kotaro Okada et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Quantitative Characterization of Crystallization in Amorphous Solid Dispersion Drug Tablets Using X-Ray Micro-Computed Tomography
- (2018) Shawn Zhang et al. MICROSCOPY AND MICROANALYSIS
- Investigation of the dependence of the Flory-Huggins interaction parameter on temperature and composition in a drug-polymer system
- (2018) Catherine Brigid Potter et al. MOLECULAR PHARMACEUTICS
- In Silico Screening for Solid Dispersions: The Trouble with Solubility Parameters and χFH
- (2018) Eleanor R. Turpin et al. MOLECULAR PHARMACEUTICS
- Relative Contributions of Solubility and Mobility to the Stability of Amorphous Solid Dispersions of Poorly Soluble Drugs: A Molecular Dynamics Simulation Study
- (2018) Michael Brunsteiner et al. Pharmaceutics
- Selection of the suitable polymer for supercritical fluid assisted preparation of carvedilol solid dispersions
- (2018) Jelena Djuris et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Formulation performance and processability window for manufacturing a dual-polymer amorphous solid dispersion via hot-melt extrusion and strand pelletization
- (2018) T.R. Hörmann et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Effects of Surfactants on Itraconazole-HPMCAS Solid Dispersion Prepared by Hot-Melt Extrusion I: Miscibility and Drug Release
- (2018) Nayan G. Solanki et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Effects of Molecular Interactions on Miscibility and Mobility of Ibuprofen in Amorphous Solid Dispersions With Various Polymers
- (2018) Tian-Xiang Xiang et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Modified Polymer Matrix in Pharmaceutical Hot Melt Extrusion by Molecular Interactions with a Carboxylic Coformer
- (2018) Felix Ditzinger et al. MOLECULAR PHARMACEUTICS
- Choosing Appropriate Solvents for ASD Preparation
- (2018) Christian Luebbert et al. MOLECULAR PHARMACEUTICS
- Impact of a Single Hydrogen Substitution by Fluorine on the Molecular Interaction and Miscibility between Sorafenib and Polymers
- (2018) Chengyu Liu et al. MOLECULAR PHARMACEUTICS
- Development of a small-scale spray-drying approach for amorphous solid dispersions (ASDs) screening in early drug development
- (2018) Aymeric Ousset et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- On the plasticizing properties of divalproex sodium: physicochemical and spectroscopic characterization studies
- (2018) Pinak Khatri et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- Evaluate the ability of PVP to inhibit crystallization of amorphous solid dispersions by density functional theory and experimental verify
- (2017) Bing Wang et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- A comparative assessment of nanocomposites vs. amorphous solid dispersions prepared via nanoextrusion for drug dissolution enhancement
- (2017) Meng Li et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Glass-forming ability of compounds in marketed amorphous drug products
- (2017) Nicole Wyttenbach et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Application of miscibility analysis and determination of Soluplus solubility map for development of carvedilol-loaded nanofibers
- (2017) Olivera Kaljević et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- A rational approach towards development of amorphous solid dispersions: Experimental and computational techniques
- (2017) Paroma Chakravarty et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Moisture-induced phase separation and recrystallization in amorphous solid dispersions
- (2017) Christian Luebbert et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Water-induced phase separation of miconazole-poly (vinylpyrrolidone-co-vinyl acetate) amorphous solid dispersions: Insights with confocal fluorescence microscopy
- (2017) Sugandha Saboo et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Molecular Dynamics Simulation of Amorphous Hydroxypropylmethylcellulose and Its Mixtures With Felodipine and Water
- (2017) Tian-Xiang Xiang et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- A New Method of Constructing a Drug–Polymer Temperature–Composition Phase Diagram Using Hot-Melt Extrusion
- (2017) Yiwei Tian et al. MOLECULAR PHARMACEUTICS
- Understanding the Impact of Water on the Miscibility and Microstructure of Amorphous Solid Dispersions: An AFM–LCR and TEM–EDX Study
- (2017) Na Li et al. MOLECULAR PHARMACEUTICS
- Impact of Polymer Type and Relative Humidity on the Long-Term Physical Stability of Amorphous Solid Dispersions
- (2017) Kristin Lehmkemper et al. MOLECULAR PHARMACEUTICS
- Insights into Water-Induced Phase Separation in Itraconazole–Hydroxypropylmethyl Cellulose Spin Coated and Spray Dried Dispersions
- (2017) Naila A. Mugheirbi et al. MOLECULAR PHARMACEUTICS
- Amorphous-Amorphous Phase Separation in API/Polymer Formulations
- (2017) Christian Luebbert et al. MOLECULES
- Polymer/Amorphous Salt Solid Dispersions of Ciprofloxacin
- (2017) Hanah Mesallati et al. PHARMACEUTICAL RESEARCH
- Phase Behavior of Ritonavir Amorphous Solid Dispersions during Hydration and Dissolution
- (2017) Hitesh S. Purohit et al. PHARMACEUTICAL RESEARCH
- Insights into Nano- and Micron-Scale Phase Separation in Amorphous Solid Dispersions Using Fluorescence-Based Techniques in Combination with Solid State Nuclear Magnetic Resonance Spectroscopy
- (2017) Hitesh S. Purohit et al. PHARMACEUTICAL RESEARCH
- Optimising Drug Solubilisation in Amorphous Polymer Dispersions: Rational Selection of Hot-melt Extrusion Processing Parameters
- (2016) Shu Li et al. AAPS PHARMSCITECH
- Hot melt extruded Aprepitant–Soluplus solid dispersion: preformulation considerations, stability andin vitrostudy
- (2016) Sai Sumana Penumetcha et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Hot melt extrusion versus spray drying: hot melt extrusion degrades albendazole
- (2016) Soraya Hengsawas Surasarang et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Influence of PVP/VA copolymer composition on drug–polymer solubility
- (2016) Malte Bille Rask et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Theoretical and experimental investigation of drug-polymer interaction and miscibility and its impact on drug supersaturation in aqueous medium
- (2016) Shrawan Baghel et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Solid state drug-polymer miscibility studies using the model drug ABT-102
- (2016) Rajan Jog et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Unexpected solvent impact in the crystallinity of praziquantel / poly(vinylpyrrolidone) formulations. A solubility, DSC and solid-state NMR study
- (2016) Emanuel D. Costa et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Statistical Analysis of a Method to Predict Drug–Polymer Miscibility
- (2016) Matthias Manne Knopp et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Support Tools in Formulation Development for Poorly Soluble Drugs
- (2016) Gudrun A. Fridgeirsdottir et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- A Promising New Method to Estimate Drug-Polymer Solubility at Room Temperature
- (2016) Matthias Manne Knopp et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Polymeric Amorphous Solid Dispersions: A Review of Amorphization, Crystallization, Stabilization, Solid-State Characterization, and Aqueous Solubilization of Biopharmaceutical Classification System Class II Drugs
- (2016) Shrawan Baghel et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Solubility parameter-based screening methods for early-stage formulation development of itraconazole amorphous solid dispersions
- (2016) Piero Piccinni et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Long-Term Physical Stability of PVP- and PVPVA-Amorphous Solid Dispersions
- (2016) Kristin Lehmkemper et al. MOLECULAR PHARMACEUTICS
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- (2016) Tian Xie et al. MOLECULAR PHARMACEUTICS
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- (2016) Na Li et al. MOLECULAR PHARMACEUTICS
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- (2016) Bin Tian et al. MOLECULAR PHARMACEUTICS
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- (2016) Muqdad Alhijjaj et al. PHARMACEUTICAL RESEARCH
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- (2016) Yuejie Chen et al. PHARMACEUTICAL RESEARCH
- Construction and Validation of Binary Phase Diagram for Amorphous Solid Dispersion Using Flory–Huggins Theory
- (2015) Krishna Bansal et al. AAPS PHARMSCITECH
- Effect of hydrophilic additives on the dissolution and pharmacokinetic properties of itraconazole-enteric polymer hot-melt extruded amorphous solid dispersions
- (2015) Bo Lang et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Combined application of mixture experimental design and artificial neural networks in the solid dispersion development
- (2015) Djordje P. Medarević et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Use of the Flory–Huggins theory to predict the solubility of nifedipine and sulfamethoxazole in the triblock, graft copolymer Soluplus
- (2015) Mohammad A. Altamimi et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
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- (2015) Jiannan Lu et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Investigation and correlation of drug polymer miscibility and molecular interactions by various approaches for the preparation of amorphous solid dispersions
- (2015) Fan Meng et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
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- (2015) Fan Meng et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
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- (2015) K. Wlodarski et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Cosolvency approach for assessing the solubility of drugs in poly(vinylpyrrolidone)
- (2015) Xin Chen et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
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- (2015) Kenjirou Higashi et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Influence of Polymer Molecular Weight on Drug–polymer Solubility: A Comparison between Experimentally Determined Solubility in PVP and Prediction Derived from Solubility in Monomer
- (2015) Matthias Manne Knopp et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Application of Film-Casting Technique to Investigate Drug–Polymer Miscibility in Solid Dispersion and Hot-Melt Extrudate
- (2015) Tapan Parikh et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Evaluation of Drug–Polymer Solubility Curves Through Formal Statistical Analysis: Comparison of Preparation Techniques
- (2015) Matthias Manne Knopp et al. JOURNAL OF PHARMACEUTICAL SCIENCES
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- (2015) Matthias Manne Knopp et al. MOLECULAR PHARMACEUTICS
- Phase Separation Kinetics in Amorphous Solid Dispersions Upon Exposure to Water
- (2015) Hitesh S. Purohit et al. MOLECULAR PHARMACEUTICS
- Miscibility of Itraconazole–Hydroxypropyl Methylcellulose Blends: Insights with High Resolution Analytical Methodologies
- (2015) Hitesh S. Purohit et al. MOLECULAR PHARMACEUTICS
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- (2015) Julie L. Calahan et al. MOLECULAR PHARMACEUTICS
- Predicting the Solubility Advantage of Amorphous Pharmaceuticals: A Novel Thermodynamic Approach
- (2015) Raphael Paus et al. MOLECULAR PHARMACEUTICS
- Hydrogen Bonding Interactions in Amorphous Indomethacin and Its Amorphous Solid Dispersions with Poly(vinylpyrrolidone) and Poly(vinylpyrrolidone-co-vinyl acetate) Studied Using 13C Solid-State NMR
- (2015) Xiaoda Yuan et al. MOLECULAR PHARMACEUTICS
- An Investigation into the Role of Polymeric Carriers on Crystal Growth within Amorphous Solid Dispersion Systems
- (2015) Yiwei Tian et al. MOLECULAR PHARMACEUTICS
- An Investigation of Nifedipine Miscibility in Solid Dispersions Using Raman Spectroscopy
- (2015) Sujinda Keratichewanun et al. PHARMACEUTICAL RESEARCH
- Molecular Interaction Studies of Amorphous Solid Dispersions of the Antimelanoma Agent Betulinic Acid
- (2014) Meiki Yu et al. AAPS PHARMSCITECH
- Extruded Soluplus/SIM as an oral delivery system: characterization, interactions,in vitroandin vivoevaluations
- (2014) Yuanyuan Zhang et al. DRUG DELIVERY
- Solubility of crystalline organic compounds in high and low molecular weight amorphous matrices above and below the glass transition by zero enthalpy extrapolation
- (2014) Youness Amharar et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Structural and Dynamic Properties of Amorphous Solid Dispersions: The Role of Solid-State Nuclear Magnetic Resonance Spectroscopy and Relaxometry
- (2014) Amrit Paudel et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Amorphous Stabilization and Dissolution Enhancement of Amorphous Ternary Solid Dispersions: Combination of Polymers Showing Drug–Polymer Interaction for Synergistic Effects
- (2014) Dev Prasad et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Effect of Different “States” of Sorbed Water on Amorphous Celecoxib
- (2014) Ganesh Shete et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- The Influence of Drug Physical State on the Dissolution Enhancement of Solid Dispersions Prepared Via Hot-Melt Extrusion: A Case Study Using Olanzapine
- (2014) Maria Fátima Pina et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- A Fast and Reliable Empirical Approach for Estimating Solubility of Crystalline Drugs in Polymers for Hot Melt Extrusion Formulations
- (2014) Samuel O. Kyeremateng et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Molecular Implications of Drug–Polymer Solubility in Understanding the Destabilization of Solid Dispersions by Milling
- (2014) Ziyi Yang et al. MOLECULAR PHARMACEUTICS
- Thermodynamic Phase Behavior of API/Polymer Solid Dispersions
- (2014) Anke Prudic et al. MOLECULAR PHARMACEUTICS
- Molecular Indicators of Surface and Bulk Instability of Hot Melt Extruded Amorphous Solid Dispersions
- (2014) Ziyi Yang et al. PHARMACEUTICAL RESEARCH
- Probing the Effects of Experimental Conditions on the Character of Drug-Polymer Phase Diagrams Constructed Using Flory-Huggins Theory
- (2014) Conor Donnelly et al. PHARMACEUTICAL RESEARCH
- Hot Melt Extruded Amorphous Solid Dispersion of Posaconazole with Improved Bioavailability: Investigating Drug-Polymer Miscibility with Advanced Characterisation
- (2014) Ritesh Fule et al. Biomed Research International
- Solubility advantage from amorphous etoricoxib solid dispersions
- (2013) Prateek Dani et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Investigation and correlation of physical stability, dissolution behaviour and interaction parameter of amorphous solid dispersions of telmisartan: A drug development perspective
- (2013) R. Dukeck et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Development of PVP/PEG mixtures as appropriate carriers for the preparation of drug solid dispersions by melt mixing technique and optimization of dissolution using artificial neural networks
- (2013) Panagiotis Barmpalexis et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Improved group contribution parameter set for the application of solubility parameters to melt extrusion
- (2013) Susann Just et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Miniaturized screening of polymers for amorphous drug stabilization (SPADS): Rapid assessment of solid dispersion systems
- (2013) Nicole Wyttenbach et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Investigation of griseofulvin and hydroxypropylmethyl cellulose acetate succinate miscibility in ball milled solid dispersions
- (2013) Hisham Al-Obaidi et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- PDFgetX3: a rapid and highly automatable program for processing powder diffraction data into total scattering pair distribution functions
- (2013) P. Juhás et al. JOURNAL OF APPLIED CRYSTALLOGRAPHY
- Effect of plasticiser type on the hot melt extrusion of venlafaxine hydrochloride
- (2013) Melina Bounartzi et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Using Flory-Huggins phase diagrams as a pre-formulation tool for the production of amorphous solid dispersions: a comparison between hot-melt extrusion and spray drying
- (2013) Yiwei Tian et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Isothermal Microcalorimetry To Investigate the Phase Separation for Amorphous Solid Dispersions of AMG 517 with HPMC-AS
- (2013) Julie L. Calahan et al. MOLECULAR PHARMACEUTICS
- Investigating Miscibility and Molecular Mobility of Nifedipine-PVP Amorphous Solid Dispersions Using Solid-State NMR Spectroscopy
- (2013) Xiaoda Yuan et al. MOLECULAR PHARMACEUTICS
- The Optimization of an Intravaginal Ring Releasing Progesterone Using a Mathematical Model
- (2013) Ignacio M. Helbling et al. PHARMACEUTICAL RESEARCH
- Rapid Assessment of Homogeneity and Stability of Amorphous Solid Dispersions by Atomic Force Microscopy—From Bench to Batch
- (2013) Matthias E. Lauer et al. PHARMACEUTICAL RESEARCH
- Prediction of acetaminophen’s solubility in poly(ethylene oxide) at room temperature using the Flory–Huggins theory
- (2012) Min Yang et al. DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
- Can compression induce demixing in amorphous solid dispersions? A case study of naproxen–PVP K25
- (2012) Zelalem Ayenew et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Optimizing the ability of PVP/PEG mixtures to be used as appropriate carriers for the preparation of drug solid dispersions by melt mixing technique using artificial neural networks: I
- (2012) Sofia A. Papadimitriou et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Miscibility analysis of particulate solid dispersions prepared by electrospray deposition
- (2012) Kohsaku Kawakami INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Drug–polymer intermolecular interactions in hot-melt extruded solid dispersions
- (2012) Mohammed Maniruzzaman et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Miscibility Studies of Indomethacin and Eudragit® E PO by Thermal, Rheological, and Spectroscopic Analysis
- (2012) Huiju Liu et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Amorphous-State Characterization of Efavirenz—Polymer Hot-Melt Extrusion Systems for Dissolution Enhancement
- (2012) Sateesh Kumar Sathigari et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- A Method to Predict the Equilibrium Solubility of Drugs in Solid Polymers near Room Temperature Using Thermal Analysis
- (2012) Robert A. Bellantone et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Nanoscale Mid-Infrared Imaging of Phase Separation in a Drug–Polymer Blend
- (2012) Bernard Van Eerdenbrugh et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Molecular Dynamics Simulation of Amorphous Indomethacin-Poly(Vinylpyrrolidone) Glasses: Solubility and Hydrogen Bonding Interactions
- (2012) Tian-Xiang Xiang et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Relating Hydrogen-Bonding Interactions with the Phase Behavior of Naproxen/PVP K 25 Solid Dispersions: Evaluation of Solution-Cast and Quench-Cooled Films
- (2012) Amrit Paudel et al. MOLECULAR PHARMACEUTICS
- Construction of Drug–Polymer Thermodynamic Phase Diagrams Using Flory–Huggins Interaction Theory: Identifying the Relevance of Temperature and Drug Weight Fraction to Phase Separation within Solid Dispersions
- (2012) Yiwei Tian et al. MOLECULAR PHARMACEUTICS
- A New Protocol To Determine the Solubility of Drugs into Polymer Matrixes
- (2012) Aurélien Mahieu et al. MOLECULAR PHARMACEUTICS
- Understanding the Tendency of Amorphous Solid Dispersions to Undergo Amorphous–Amorphous Phase Separation in the Presence of Absorbed Moisture
- (2011) Alfred C. F. Rumondor et al. AAPS PHARMSCITECH
- Evaluation of amorphous solid dispersion properties using thermal analysis techniques
- (2011) Jared A. Baird et al. ADVANCED DRUG DELIVERY REVIEWS
- Interplay of formulation and process methodology on the extent of nifedipine molecular dispersion in polymers
- (2011) Jingjun Huang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Informatics calibration of a molecular descriptors database to predict solid dispersion potential of small molecule organic solids
- (2011) Michael D. Moore et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Thermal processing of a poorly water-soluble drug substance exhibiting a high melting point: The utility of KinetiSol® Dispersing
- (2011) Justin R. Hughey et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- The future of molecular dynamics simulations in drug discovery
- (2011) David W. Borhani et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Prediction of the Thermal Phase Diagram of Amorphous Solid Dispersions by Flory–Huggins Theory
- (2011) Yinyan Zhao et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- A Comparison of Spray Drying and Milling in the Production of Amorphous Dispersions of Sulfathiazole/Polyvinylpyrrolidone and Sulfadimidine/Polyvinylpyrrolidone
- (2011) Vincent Caron et al. MOLECULAR PHARMACEUTICS
- Compositional Analysis of Low Quantities of Phase Separation in Hot-Melt-Extruded Solid Dispersions: A Combined Atomic Force Microscopy, Photothermal Fourier-Transform Infrared Microspectroscopy, and Localised Thermal Analysis Approach
- (2011) Sheng Qi et al. PHARMACEUTICAL RESEARCH
- Data Requirements for the Reliable Use of Atomic Pair Distribution Functions in Amorphous Pharmaceutical Fingerprinting
- (2011) Timur Dykhne et al. PHARMACEUTICAL RESEARCH
- Influence of Solvent Composition on the Miscibility and Physical Stability of Naproxen/PVP K 25 Solid Dispersions Prepared by Cosolvent Spray-Drying
- (2011) Amrit Paudel et al. PHARMACEUTICAL RESEARCH
- Is a distinctive single Tg a reliable indicator for the homogeneity of amorphous solid dispersion?
- (2010) Feng Qian et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Solid dispersion of acetaminophen and poly(ethylene oxide) prepared by hot-melt mixing
- (2010) Min Yang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Solubilities of Crystalline Drugs in Polymers: An Improved Analytical Method and Comparison of Solubilities of Indomethacin and Nifedipine in PVP, PVP/VA, and PVAc
- (2010) Ye Sun et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- A Classification System to Assess the Crystallization Tendency of Organic Molecules from Undercooled Melts
- (2010) Jared A. Baird et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Drug–Polymer Solubility and Miscibility: Stability Consideration and Practical Challenges in Amorphous Solid Dispersion Development
- (2010) Feng Qian et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Using Molecular Simulations to Probe Pharmaceutical Materials
- (2010) Yong Cui JOURNAL OF PHARMACEUTICAL SCIENCES
- The Study of Phase Separation in Amorphous Freeze-Dried Systems. Part I: Raman Mapping and Computational Analysis of XRPD Data in Model Polymer Systems
- (2010) Adora M. Padilla et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Physicochemical Properties of the Amorphous Drug, Cast Films, and Spray Dried Powders to Predict Formulation Probability of Success for Solid Dispersions: Etravirine
- (2010) Ilse Weuts et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Review: physical chemistry of solid dispersions
- (2010) Sandrien Janssens et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Pharmaceutical applications of cyclodextrins: basic science and product development
- (2010) Thorsteinn Loftsson et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Theoretical and Experimental Investigation on the Solid Solubility and Miscibility of Naproxen in Poly(vinylpyrrolidone)
- (2010) Amrit Paudel et al. MOLECULAR PHARMACEUTICS
- Analysis of Amorphous Solid Dispersions Using 2D Solid-State NMR and1HT1Relaxation Measurements
- (2010) Tran N. Pham et al. MOLECULAR PHARMACEUTICS
- Predicting the Formation and Stability of Amorphous Small Molecule Binary Mixtures from Computationally Determined Flory−Huggins Interaction Parameter and Phase Diagram
- (2010) Katja Pajula et al. MOLECULAR PHARMACEUTICS
- Structural Interpretation in Composite Systems Using Powder X-ray Diffraction: Applications of Error Propagation to the Pair Distribution Function
- (2010) Michael D. Moore et al. PHARMACEUTICAL RESEARCH
- Atomic Force Microscopy-Based Screening of Drug-Excipient Miscibility and Stability of Solid Dispersions
- (2010) Matthias Eckhard Lauer et al. PHARMACEUTICAL RESEARCH
- Characterisation and Prediction of Phase Separation in Hot-Melt Extruded Solid Dispersions: A Thermal, Microscopic and NMR Relaxometry Study
- (2010) Sheng Qi et al. PHARMACEUTICAL RESEARCH
- Influence of Preparation Methods on Solid State Supersaturation of Amorphous Solid Dispersions: A Case Study with Itraconazole and Eudragit E100
- (2010) Sandrien Janssens et al. PHARMACEUTICAL RESEARCH
- Characterisation of amorphous and nanocrystalline molecular materials by total scattering
- (2009) Simon J. L. Billinge et al. CRYSTENGCOMM
- Spray drying from complex solvent systems broadens the applicability of Kollicoat IR as a carrier in the formulation of solid dispersions
- (2009) Sandrien Janssens et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Relating solubility data of parabens in liquid PEG 400 to the behaviour of PEG 4000-parabens solid dispersions
- (2009) Johan Unga et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- An improved kinetics approach to describe the physical stability of amorphous solid dispersions
- (2009) Jiao Yang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Novel methods for the assessment of miscibility of amorphous drug-polymer dispersions
- (2009) Igor Ivanisevic et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Miscibility/stability considerations in binary solid dispersion systems composed of functional excipients towards the design of multi-component amorphous systems
- (2009) Seung-uk Yoo et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Amorphous Drug-PVP Dispersions: Application of Theoretical, Thermal and Spectroscopic Analytical Techniques to the Study of a Molecule With Intermolecular Bonds in Both the Crystalline and Pure Amorphous State
- (2009) Michael Tobyn et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Physicochemical Characterization of Hot Melt Extruded Bicalutamide–Polyvinylpyrrolidone Solid Dispersions
- (2009) Gavin P. Andrews et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Effect of temperature and moisture on the miscibility of amorphous dispersions of felodipine and poly(vinyl pyrrolidone)
- (2009) Patrick J. Marsac et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Phase Behavior of Poly(vinylpyrrolidone) Containing Amorphous Solid Dispersions in the Presence of Moisture
- (2009) Alfred C. F. Rumondor et al. MOLECULAR PHARMACEUTICS
- Effect of Polymer Hygroscopicity on the Phase Behavior of Amorphous Solid Dispersions in the Presence of Moisture
- (2009) Alfred C. F. Rumondor et al. MOLECULAR PHARMACEUTICS
- Evaluation of Drug-Polymer Miscibility in Amorphous Solid Dispersion Systems
- (2009) Alfred C. F. Rumondor et al. PHARMACEUTICAL RESEARCH
- Improved dissolution of a poorly water soluble drug in solid dispersions with polymeric and non-polymeric hydrophilic additives
- (2008) Garima Chawla et al. ACTA PHARMACEUTICA
- Citric acid monohydrate as a release-modifying agent in melt extruded matrix tablets
- (2008) Sandra U. Schilling et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Miscibility and interactions between 17β-estradiol and Eudragit® RS in solid dispersion
- (2008) Chutima Wiranidchapong et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Characterization of amorphous API:Polymer mixtures using X-ray powder diffraction
- (2008) Ann Newman et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Pair distribution function X‐ray analysis explains dissolution characteristics of felodipine melt extrusion products
- (2008) K. Nollenberger et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Application of Melt Extrusion in the Development of a Physically and Chemically Stable High-Energy Amorphous Solid Dispersion of a Poorly Water-Soluble Drug
- (2008) Jay P. Lakshman et al. MOLECULAR PHARMACEUTICS
- Amorphous Compositions Using Concentration Enhancing Polymers for Improved Bioavailability of Itraconazole
- (2008) James C. DiNunzio et al. MOLECULAR PHARMACEUTICS
- Estimation of Drug Solubility in Polymers via Differential Scanning Calorimetry and Utilization of the Fox Equation
- (2008) Raja Haddadin et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- Characterization and Physical Stability of Spray Dried Solid Dispersions of Probucol and PVP-K30
- (2008) Pia Thybo et al. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY
- Solubility of Small-Molecule Crystals in Polymers: d-Mannitol in PVP, Indomethacin in PVP/VA, and Nifedipine in PVP/VA
- (2008) Jing Tao et al. PHARMACEUTICAL RESEARCH
- Estimation of Drug–Polymer Miscibility and Solubility in Amorphous Solid Dispersions Using Experimentally Determined Interaction Parameters
- (2008) Patrick J. Marsac et al. PHARMACEUTICAL RESEARCH
- Targeted Intestinal Delivery of Supersaturated Itraconazole for Improved Oral Absorption
- (2008) Dave A. Miller et al. PHARMACEUTICAL RESEARCH
- Role of Thermodynamic, Molecular, and Kinetic Factors in Crystallization from the Amorphous State
- (2007) Chandan Bhugra et al. JOURNAL OF PHARMACEUTICAL SCIENCES
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