Review
Chemistry, Multidisciplinary
Anca Giorgiana Grigoras
Summary: The overuse of antibiotics leading to antimicrobial resistance has prompted scientists to develop new antimicrobials with longer duration of action and minimal environmental toxicity, such as polymers modified with quaternary ammonium moieties. These new antimicrobials interact better with and inhibit microorganisms through their net positive charge, with research also focusing on using other functional groups in synergy to improve efficiency.
ENVIRONMENTAL CHEMISTRY LETTERS
(2021)
Review
Biotechnology & Applied Microbiology
Rula M. Darwish, Mohammad AlMasri, Mahmoud M. Al-Masri
Summary: This article reviews the progress of studies on mucormycosis and highlights important findings in relation to epidemiology, clinical manifestation, major risk factors, diagnostic strategies, and management. The diagnosis of mucormycosis is difficult, and surgical debridement prior to infection dissemination is crucial for improving clinical outcomes. Identifying underlying risk factors is important for proper treatment. There are limited antifungal therapeutic options, with polyenes and their combinations being appropriate for empirical therapy, while posaconazole and isavuconazole are best reserved for de-escalation, refractory cases, or patients intolerant to amphotericin B.
JOURNAL OF APPLIED MICROBIOLOGY
(2022)
Article
Food Science & Technology
Tiago Melo Nazareth, Raquel Torrijos, Karla Paiva Bocate, Jordi Manes, Fernando Bittencourt Luciano, Giuseppe Meca, Pilar Vila-Donat
Summary: The present study describes the manufacture of an antifungal device composed of oriental mustard flour and hydroxyethyl-cellulose (H-OMF) and evaluates its efficacy in inhibiting Aspergillus flavus growth and aflatoxin B1 (AFB(1)) production in almonds. The device showed significant antifungal activity and could effectively reduce the population of A. flavus and the production of AFB(1) in almonds.
Article
Food Science & Technology
Alberto Bombelli, Carla Araya-Cloutier, Jean-Paul Vincken, Tjakko Abee, Heidy M. W. den Besten
Summary: The study investigated the potential of glabridin and 6,8-diprenylgenistein as food preservatives against L. monocytogenes. The results showed that both compounds exhibited antimicrobial activity under various conditions, especially at lower temperatures and pH levels.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2023)
Review
Biotechnology & Applied Microbiology
Bilal Murtaza, Xiaoyu Li, Liming Dong, Muhammad Tariq Javed, Le Xu, Muhammad Kashif Saleemi, Gen Li, Bowen Jin, Huijing Cui, Ashiq Ali, Lili Wang, Yongping Xu
Summary: Zearalenone (ZEN) contamination of foods and feeds is a global problem that requires removal or degradation. Traditional physical and chemical methods have issues, while biodegradation using microorganisms and their enzymes is more advantageous and environmentally friendly. Existing research indicates that enzymes produced by microorganisms play a significant role in degrading mycotoxins such as ZEN.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2022)
Article
Microbiology
Azmi Khan, Pratika Singh, Ravinsh Kumar, Sujit Das, Rakesh Kumar Singh, Usha Mina, Ganesh Kumar Agrawal, Randeep Rakwal, Abhijit Sarkar, Amrita Srivastava
Summary: The study assessed the antifungal activity of catecholate siderophore produced by Escherichia coli against Aspergillus nidulans. The findings showed that the siderophore treatment inhibited fungal growth, induced cell death, and affected antioxidative enzyme activity. This suggests a promising antifungal agent in catecholate siderophore and supports the involvement of MirA fungal receptors in xenosiderophore uptake.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Food Science & Technology
Carlos Enrique Ochoa-Velasco, Julio Cesar Perez-Perez, Jose Mauricio Varillas-Torres, Addi Rhode Navarro-Cruz, Paola Hernandez-Carranza, Ricardo Munguia-Perez, Teresa Soledad Cid-Perez, Raul Avila-Sosa
Summary: This study evaluated the effectiveness of thymol and carvacrol against Colletotrichum gloeosporioides in edible films and coatings. In vitro evaluation showed MIC values of the compounds at different pH levels, with additive effects observed in binary mixtures. In vivo evaluation on mango and papaya demonstrated delayed fruit ripening and reduced disease symptoms, indicating the potential of thymol and carvacrol in controlling anthracnose.
Article
Food Science & Technology
Anna Carolina Leonelli Pires de Campos, Renata Daniela Saldanha Nandi, Sara Scandorieiro, Marcelly Chue Goncalves, Guilherme Fonseca Reis, Miriam Dibo, Leonardo Pinto Medeiros, Luciano Aparecido Panagio, Eder Paulo Fagan, Renata Katsuko, Takayama Kobayashi, Gerson Nakazato
Summary: This study evaluated the antimicrobial activity of oregano essential oil (OEO) against bacteria and fungi in ripened cheeses, and found that OEO at a concentration of 0.02% (v/v) was effective in controlling pathogenic bacteria, multidrug-resistant bacteria, and toxigenic fungi during cheese ripening.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Review
Infectious Diseases
Olga M. Tsivileva, Oleg Koftin, Nina Evseeva
Summary: Coumarin derivatives have wide practical application and unique reactivity. More than 1300 coumarins have been identified in plants, bacteria, and fungi. Fungal coumarins, with their promising therapeutic potential in fields such as cancer and microbial infections, deserve further study.
Article
Biotechnology & Applied Microbiology
Douglas Roberto Monteiro, Victor Eduardo de Souza Batista, Anne Caroline Morais Caldeirao, Rogerio de Castilho Jacinto, Juliano Pelim Pessan
Summary: The oral cavity is a complex ecosystem, and using prosthetic devices due to missing teeth may alter microbial diversity. Biofilms on the surface of prosthetic devices can change material properties and lead to local or systemic diseases for prosthetic wearers.
Review
Food Science & Technology
Fabiola Ayres Cacciatore, Adriano Brandelli, Patricia da Silva Malheiros
Summary: Combining natural antimicrobials with nanotechnological strategies offers an alternative approach for food surface disinfection and prevents microbial biofilm formation. Despite some difficulties, this method demonstrates a great potential in the food industry.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2021)
Article
Chemistry, Applied
Luis Fernando Wentz Brum, Cristiane dos Santos, Joao Henrique Zimnoch Santos, Adriano Brandelli
Summary: Nisin was successfully encapsulated in mesoporous nanostructures of silica through acid-catalyzed sol-gel process, retaining its antimicrobial activity. Variations in particle diameter, ζ potential, surface area, and pore characteristics of silica particles indicate successful encapsulation.
Review
Food Science & Technology
Adriano Brandelli, Nathalie Almeida Lopes, Cristian Mauricio Barreto Pinilla
Summary: In the food sector, the dairy industry is an important economic activity that faces challenges in meeting consumer demand for natural and high quality products. To address these challenges, the application of innovative technologies, such as nanotechnology, can improve the quality and safety of dairy products. This review provides examples and promising results of using nanotechnology in dairy product preservation, including the use of nanoparticles and nanofilms. Despite the high cost and scale-up difficulties, these technologies have generated interest in the dairy industry.
Review
Food Science & Technology
Rickyn A. Jacinto-Valderrama, Cristina T. Andrade, Mirian Pateiro, Jose M. Lorenzo, Carlos Adam Conte-Junior
Summary: This article discusses the challenges in muscle-food preservation and the application of active-packaging technology in muscle foods. It also examines the use of nano-sized active substances in muscle-food packaging and the extension of shelf life and inhibitory effects on oxidation and microbial growth during storage.
Article
Biochemistry & Molecular Biology
Li-Juan Zhang, Ming-Fei Yang, Jian Ma, Xing-Juan Xiao, Xiao-Yan Ma, De-Ge Zheng, Mei-Yan Han, Ming-Lei Xia, Ruvishika S. Jayawardena, Ausana Mapook, Yuan-Pin Xiao, Ji-Chuan Kang, Yong-Zhong Lu
Summary: Two new polyketides, neogrisphenol A (1) and neogrisphenol B (2), one new isochroman-1-one (3), and four known compounds (4-7) were isolated from the rice fermentation product of Neohelicosporium griseum, a new record fungus. Their structures were determined using various analytical techniques. Compounds 1-2 and 5 showed antibacterial activity against multiple bacteria strains, while compound 5 exhibited antifungal activity against two different fungi strains. Compound 1 also demonstrated significant cytotoxicity against several cancer cell lines.
Review
Food Science & Technology
Gabriela Maia Danielski, Alberto Goncalves Evangelista, Fernando Bittencourt Luciano, Renata Ernlund Freitas de Macedo
Summary: Meat and meat products are susceptible to pathogenic or spoilage bacteria, causing economic losses and public health threats. Non-conventional microorganisms and biometabolites have potential for bio protection, improving the quality and safety of meat products.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Food Science & Technology
Alberto Goncalves Evangelista, Jessica Audrey Feijo Correa, Anne Caroline Schoch Marques Pinto, Fernando Bittencourt Luciano
Summary: Population growth affects global food supply by demanding higher production efficiency without expanding farmland due to limited land resources and biodiversity loss. The intense use of antibiotic growth promoters in animal production has been linked to antimicrobial resistance rise, leading to the emergence of multidrug-resistant pathogens and limiting treatment options. Essential oils and essential oil components have been studied as potential alternatives to antibiotics in animal production, showing antimicrobial effectiveness and potential for improving zootechnical indexes and modulating genes involved in resistance mechanisms.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Food Science & Technology
Alberto Goncalves Evangelista, Karla Carolina Paiva Bocate, Giuseppe Meca, Fernando Bittencourt Luciano
Summary: Combining AITC and CIN shows potential in inhibiting mycotoxigenic fungi and reducing aflatoxins production, with AITC being very pungent and the combination with CIN helping to mask its strong odor to improve acceptance.
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2021)
Review
Food Science & Technology
Alberto Goncalves Evangelista, Gabriela Maia Danielski, Jessica Audrey Feijo Correa, Caroline Maria de Andrade Cavalari, Isabelle Ramos Souza, Fernando Bittencourt Luciano, Renata Ernlund Freitas de Macedo
Summary: Carnobacterium bacteria have shown potential as probiotics and bioprotective agents, particularly in animal production and the food industry. However, research on human health applications is still in the early stages and there is a lack of in vivo studies, limiting its widespread use.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Food Science & Technology
Anne Caroline Schoch Marques Pinto, Camilla Reginatto De Pierri, Alberto Goncalves Evangelista, Ana Silvia de Lara Pires Batista Gomes, Fernando Bittencourt Luciano
Summary: Deoxynivalenol (DON) is a toxic secondary metabolite produced by fungi that contaminates crops such as wheat, maize, and barley. It affects animal health by causing intestinal barrier impairment and immunostimulatory effect in low doses, and emesis, reduction in feed conversion rate, and immunosuppression in high doses. Mitigatory methods, such as biodegradation, have been developed to address this issue. This review provides an overview of DON's occurrence, regulation, metabolism, and toxicology in recent publications, focusing on animal production. It also explores the enzymatic routes described for DON's degradation by microorganisms and their phylogenetic relationship.
Review
Nutrition & Dietetics
Natana Gengnagel, Alberto Goncalves Evangelista
Summary: This review gathers recent research on the presence of L. monocytogenes in meat and meat products in Latin America, highlighting control methods and resistance genes. Negligence in studying L. monocytogenes in meat and meat products is observed in many Latin American countries.
CURRENT NUTRITION & FOOD SCIENCE
(2022)
Review
Nutrition & Dietetics
Raphael Jayson Prestes, Alberto Goncalves Evangelista
Summary: Over the years, human rights have been internalized by institutions and legislation worldwide, but more needs to be done in practice. In Brazil, there is a wide disparity in per capita food acquisition between different regions. The use of antibiotics in animal production can also pose health risks. This work aims to defend the good nutrition of Brazilians.
CURRENT NUTRITION & FOOD SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Maria Carolina Stipp, Juliana Danna Kulik, Claudia Rita Corso, Claudia Martins Galindo, Eliana Rezende Adami, Alberto Goncalves Evangelista, Fernando Bittencourt Luciano, Sheila Maria Brochado Winnischofer, Silvia Maria Suter Correia Cadena, Guilherme Lanzi Sassaki, Alexandra Acco
Summary: The soluble fraction of polysaccharides from cabernet franc red wine (SFP) has been found to have antitumoral effects by modulating the immune system. This study confirms that SFP can regulate CYPs both in vitro and in vivo. The results suggest that SFP inhibits CYPs likely through its immunoinflammatory actions.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Veterinary Sciences
Alberto Goncalves Evangelista, Eduardo Henrique Custodio Matte, Jessica Audrey Feijo Correa, Francieli Dalvana Ribeiro Goncalves, Joao Vitor Garcia dos Santos, Gabrieli Camila Biauki, Monica Moura Milek, Leandro Batista Costa, Fernando Bittencourt Luciano
Summary: This research isolated lactic acid bacteria (LAB) from meat products and commercial probiotics to verify their bioprotective potential against Salmonella. Pediococcus acidilactici showed inhibitory activity against multiple Salmonella strains. Some bacteria maintained high viability after encapsulation and in vitro digestion. While the bioprotective potential of LAB was confirmed, further research is needed to determine their effectiveness in vivo.
VETERINARY RESEARCH COMMUNICATIONS
(2023)
Review
Veterinary Sciences
Eduardo Henrique Custodio Matte, Fernando Bittencourt Luciano, Alberto Goncalves Evangelista
Summary: This article reviews the use of naturally occurring essential oils and their isolated compounds as alternatives to antimicrobials and antiparasitic compounds in animal production to avoid resistance. The most-reported mechanism of action is cell membrane damage, leading to various effects such as increased membrane permeability and antibiofilm effects. These compounds can also positively impact crucial parameters in animal production and can be enhanced by combining them with other natural compounds or synthetic chemicals. However, there is a lack of research on the combination of these compounds in large in vivo studies and the correct methodology must be applied to understand their effects properly.
ANIMAL HEALTH RESEARCH REVIEWS
(2023)
Article
Biotechnology & Applied Microbiology
Alberto Gonsalves Evangelista, Lucas dos Santos Janotto, Eduardo Henrique Custodio Matte, Carolina Cini Perry, Francine Lemes Ribeiro, Fernando Bittencourt Luciano
Summary: The use of growth-promoting antibiotics has led to an increase in antimicrobial resistance, necessitating the search for new alternatives. Combining conventional and new methods provides an opportunity for innovative approaches. This study evaluated the interaction between halquinol and allyl isothiocyanate (AITC), cinnamaldehyde (CIN), and carvacrol (CA).
BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY
(2023)
