Editorial Material
Business
Madeleine Rauch, Moritz Loock, Wolfgang H. Guettel
Summary: This introduction examines the relationship between heuristics, technological forecasting, and social change. It introduces five articles included in the Special Issue on 'Heuristics in Technological Forecasting and Social Change' and proposes directions for further research. The authors highlight important, yet unexplored research questions that could enhance the study of heuristics in the context of social and technological change.
TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE
(2023)
Editorial Material
Engineering, Electrical & Electronic
Ilko Ilev, David Nolte, Qiyin Fang, Giuliano Scarcelli, Yuji Matsuura, William Calhoun, Thomas Huser
Summary: Biophotonics is an emerging and rapidly growing field of advanced biomedical technologies that encompasses a wide range of applications, from laboratory research to clinical diagnostics, bioimaging, biosensing, and therapeutics.
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
(2021)
Editorial Material
Engineering, Electrical & Electronic
Qiyin Fang, Charles Kervrann, David Nolte, Oxana Semyachkina-Glushkovskaya, Shuo Tang, Yuji Matsuura, Zachary Smith
Summary: Biophotonics is an interdisciplinary field that combines photonics and biomedical applications. It has made significant advancements in clinical diagnosis, therapeutics, biotechnology, and environmental studies. The integration of optics and biology has led to quick adoption of photonics technologies in medicine due to its compatibility with minimally invasive procedures.
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
(2023)
Editorial Material
Engineering, Electrical & Electronic
Jose Capmany, Christina Lim, Kazutosi Kato, Patrick Runge, Andreas Beling
Summary: The papers in this special section focus on optical detectors and the conversion from photons to electrons, which is a crucial operation in photonic systems. The development in the past five decades, especially based on heterostructures, quantum wells, and uni-carrier operation, has yielded impressive results in terms of bandwidth, noise, and footprint.
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
(2022)
Editorial Material
Computer Science, Hardware & Architecture
Jean-Pierre Hamaide, Christian Lerminiaux, Philippe Chanclou, Pierre Sillard
Summary: This special issue includes extensions of tutorials and invited and top-scored optical networking papers that were presented at the European Conference on Optical Communication (ECOC) 2021, held 13-16 September 2021 in Bordeaux, France.
JOURNAL OF OPTICAL COMMUNICATIONS AND NETWORKING
(2022)
Editorial Material
Computer Science, Hardware & Architecture
Ramon Casellas, Raul Munoz, Marija Furdek, Salvatore Spadaro, Zuqing Zhu
Summary: This special issue of JOCN includes extended versions of selected papers presented at the 24th International Conference on Optical Network Design and Modeling (ONDM2020), covering current trends in optical networking research such as filterless optical networks, programmable transceivers, and machine learning applications in networks.
JOURNAL OF OPTICAL COMMUNICATIONS AND NETWORKING
(2021)
Editorial Material
Acoustics
Libertario Demi, Marie Muller
Summary: The potential of lung ultrasound has been highlighted during the COVID-19 pandemic, leading to research efforts to understand and model the physical phenomena involved in ultrasound propagation for assessing lung structure changes both qualitatively and quantitatively.
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
(2021)
Editorial Material
Acoustics
James F. Lynch, Charles C. Church
Summary: In this article, 48 papers are presented, discussing the acoustical impacts of the COVID-19 pandemic and how to address them. These papers are divided into seven categories, including physical masking and speech production, speech perception, noise, the underwater soundscape, the urban soundscape, pathogen transmissibility, and medical diagnosis.
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
(2023)
Editorial Material
Engineering, Electrical & Electronic
Guillermo Carpintero, Elliott Brown, Tadao Nagatsuma, Pham Tien Dat, Lute Maleki, Daniel Yap, Andreas Stohr
Summary: This Special Issue of the IEEE/OSA Journal of Selected Topics in Quantum Electronics on Terahertz Photonics provides an overview of the latest developments in the field, covering a wide range from 100 GHz to 10 THz. Terahertz Photonics has played a leading role in accessing the Terahertz range, enabling important demonstrations in areas such as broadband communications, spectroscopy, and imaging through innovative THz sources and detectors.
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
(2023)
Editorial Material
Engineering, Civil
Stephan Olariu, Samy El-Tawab
Summary: Traffic state estimation refers to the measurement or inference of key traffic state variables, such as density, flow, speed, and delay, using a combination of observed and derived traffic-related data. Recent advancements in vehicular networking, sensor technology, and computer and communications paradigms have made real-time estimation of traffic state parameters technically feasible, yet still challenging.
IEEE TRANSACTIONS ON INTELLIGENT TRANSPORTATION SYSTEMS
(2023)
Editorial Material
Computer Science, Cybernetics
Amon Rapp, William Odom, Larissa Pschetz, Daniela Petrelli
Summary: This special issue explores new perspectives of time within HCI research, surpassing traditional views. The authors discuss how the HCI community has shifted from focusing on clock time to incorporating existential, social, and cultural dimensions of time. They also highlight open issues and opportunities that should be explored in future research and practice in HCI.
HUMAN-COMPUTER INTERACTION
(2022)
Editorial Material
Communication
Winifred R. Poster
Summary: This special issue expands research on the various forms of deception in the digital economy, focusing on the institutions, labor, and platforms involved in online scams, fakes, and frauds.
NEW MEDIA & SOCIETY
(2022)
Article
Biochemistry & Molecular Biology
Ana Vujic, Amy N. M. Koo, Hiran A. Prag, Thomas Krieg
Summary: Mitochondria play a crucial role in cellular processes and heart function, with communication between mitochondria and the nucleus maintaining cardiomyocyte homeostasis. Excessive generation of ROS can lead to irreversible cell damage, contributing to various pathologies. Additionally, myocardial impairments are associated with specific metabolic changes and dysregulated inflammatory responses.
FREE RADICAL BIOLOGY AND MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Lars-Oliver Klotz, Carsten Carlberg
Summary: This passage discusses the importance of environmental signals on the epigenomes of various tissues and cell types in our body throughout our lifespan. Diet and lifestyle choices can impact epigenome programming and redox processes, potentially leading to diseases. Nutrigenomics investigates the effects of nutrition-related signal transduction pathways on gene expression, with some interactions being regulated by redox processes.
Editorial Material
Computer Science, Hardware & Architecture
Marija Furdek, Paolo Monti, Carmen Mas Machuca, Jaroslaw Turkiewicz, David Larrabeiti
Summary: This special issue of JOCN features extended versions of selected papers from the 25th International Conference on Optical Network Design and Modeling. The papers cover various trends in optical networking research, including capacity upgrade, spectral efficiency improvement, novel network architectures, and inter-operator sharing of optical network capacity.
JOURNAL OF OPTICAL COMMUNICATIONS AND NETWORKING
(2022)
Article
Cell Biology
Helmut Sies, Vsevolod V. Belousov, Navdeep S. Chandel, Michael J. Davies, Dean P. Jones, Giovanni E. Mann, Michael P. Murphy, Masayuki Yamamoto, Christine Winterbourn
Summary: This article discusses the key issues associated with identifying the physiological roles of oxidants, with a focus on H2O2 and O-2(.-). The article emphasizes the need for more precise measurement of oxidants and specific identification of their signaling targets. It also highlights the importance of inter-organellar communication and the contribution of environmental exposures. Development of tools for real-time detection and quantification of individual oxidants is crucial for achieving these goals.
NATURE REVIEWS MOLECULAR CELL BIOLOGY
(2022)
Editorial Material
Biochemistry & Molecular Biology
Irving H. Zucker, Giovanni E. Mann, Pietro Ghezzi
FREE RADICAL BIOLOGY AND MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Eveline van Leeuwen, Mark B. Hampton, Leon C. D. Smyth
Summary: Inflammation is a common feature in neurological diseases. This study demonstrates that a compound called hypothiocyanous acid can damage brain endothelial cells and result in the loss of barrier function, which may be a mechanism involved in neutrophil transmigration and neuroinflammation.
Article
Biochemistry & Molecular Biology
Heather L. Shearer, Paul E. Pace, James C. Paton, Mark B. Hampton, Nina Dickerhof
Summary: This study reports the discovery of a previously unknown flavoprotein disulfide reductase with HOSCN reductase activity in HOSCN-tolerant Streptococcus pneumoniae, and demonstrates the role of this protein in combination with GSH utilization in protecting the bacteria from HOSCN.
JOURNAL OF BIOLOGICAL CHEMISTRY
(2022)
Article
Gastroenterology & Hepatology
A. Swaminathan, G. M. Borichevsky, T. S. Edwards, E. Hirschfeld, T. C. Mules, C. M. Frampton, A. S. Day, M. B. Hampton, A. J. Kettle, R. B. Gearry
Summary: This study investigated the use of faecal myeloperoxidase (fMPO) as a biomarker for the activity of inflammatory bowel disease (IBD). The results showed that fMPO was significantly correlated with endoscopic activity and could accurately predict the severity and complexity of the disease.
JOURNAL OF CROHNS & COLITIS
(2022)
Article
Biochemistry & Molecular Biology
Annika R. Seddon, Andrew B. Das, Mark B. Hampton, Aaron J. Stevens
Summary: Oxidative stress is a common feature of inflammation-driven cancers that modulates gene expression through the oxidation of transcription factors. Exposure to chloramines may result in decreased DNA methylation, leading to long-term impacts on cells, potentially affecting telomere length and cellular longevity.
HUMAN MOLECULAR GENETICS
(2022)
Editorial Material
Biochemistry & Molecular Biology
Antonio Cuadrado, Albena T. Dinkova-Kostova, Giovanni E. Mann
FREE RADICAL BIOLOGY AND MEDICINE
(2023)
Review
Immunology
Mark B. Hampton, Nina Dickerhof
Summary: The neutrophil phagosome poses a challenging environment for bacteria, but our understanding of the complex biochemistry within it is incomplete. Heterogeneity among phagosomes suggests that investigating the conditions that allow bacteria to survive could lead to new therapeutic strategies. Monitoring or recovering bacteria from phagosomes and unbiased screening for essential bacterial genes are important for gaining insights into their survival mechanisms inside neutrophil phagosomes.
IMMUNOLOGICAL REVIEWS
(2023)
Review
Biochemistry & Molecular Biology
Tetsuro Ishii, Eiji Warabi, Giovanni E. Mann
Summary: Low levels of oxidative stress activate Nrf2, which is a transcription factor that regulates genes involved in detoxification and defense against oxidative damage. MAP kinases p38, ERK, and JNK cooperate in the nuclear accumulation of Nrf2. Membrane trafficking and phosphorylation of Nrf2 by ceramide and PKC zeta stabilize Nrf2 and prevent nuclear export. ERK and JNK phosphorylation of Nrf2 promote its association with Pin1 and importin-alpha 5, facilitating nuclear translocation. Pin1-Hsp90 alpha complex and dynein motor complex transport Nrf2 to the nucleus along microtubules. This pathway is also involved in the transport of other proteins, such as pyruvate kinase M2 and hypoxia-inducible transcription factor-1, and may be a potential therapeutic target for tumors.
Editorial Material
Biochemistry & Molecular Biology
Gabriel E. Valdebenito, Anitta R. Chacko, Michael R. Duchen
Summary: The mitochondrial F1Fo-ATP synthase can both synthesize ATP and pump protons, with potential implications for diseases. In a recent study, Acin-Perez et al. identified (+)-epicatechin as a compound that selectively inhibits ATP hydrolysis without affecting ATP synthesis. They found that this compound has significant benefits for cell and tissue function in disease models, suggesting a novel therapeutic approach for mitochondrial disease.
Article
Biochemistry & Molecular Biology
Heather L. Shearer, Vu V. Loi, Paul Weiland, Gert Bange, Florian Altegoer, Mark B. Hampton, Haike Antelmann, Nina Dickerhof
Summary: A study reveals that Staphylococcus aureus has developed a defense mechanism against the antimicrobial oxidant hypothiocyanous acid (HOSCN) in order to cause infections in humans. The enzyme MerA acts as a HOSCN reductase, protecting the bacteria from oxidative stress. Understanding the structure and function of MerA may lead to new strategies for treating S. aureus infections.
MOLECULAR MICROBIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Matthew J. Smith, Fan Yang, Alexander Griffiths, Alexander Morrell, Sarah J. Chapple, Richard C. M. Siow, Theodora Stewart, Wolfgang Maret, Giovanni E. Mann
Summary: Zinc is vital for cellular antioxidant defenses and imbalanced zinc homeostasis increases the risk of coronary heart disease and ischemia/reperfusion injury. In human coronary artery cells, the total intracellular zinc content decreases significantly when oxygen levels are lowered. This is accompanied by differences in redox phenotype and metal profiles, indicating the involvement of NRF2 signaling in zinc regulation.
Review
Microbiology
Carmen Gonzalez-Bosch, Patricia A. Zunszain, Giovanni E. Mann
Summary: Breast cancer is a major cause of death in women worldwide, and there is a need for new alternative therapies. Plant-derived compounds, such as flavonoids and polyphenols, have gained increasing interest for their antioxidant properties and ability to regulate cell homeostasis. Short-chain fatty acids (SCFAs), produced by intestinal microbiota and obtained from the diet, also play a crucial role in redox signaling and cancer prevention. This review focuses on the antioxidant properties of SCFAs and their impact on breast cancer development and treatment.
Article
Microbiology
Heather L. Shearer, Paul E. Pace, Leah M. Smith, Peter C. Fineran, Allison J. Matthews, Andrew Camilli, Nina Dickerhof, Mark B. Hampton
Summary: By using saturation transposon mutagenesis and deep sequencing, this study identified 37 genes associated with hypothiocyanous acid (HOSCN) tolerance in Streptococcus pneumoniae. These genes are involved in metabolism, membrane transport, DNA repair, and oxidant detoxification. Validation experiments showed that most of the single-gene deletion mutants exhibited increased sensitivity to HOSCN, and some mutants showed enhanced activity of antioxidant defense systems. The double deletion of glutathione reductase and sodA significantly sensitized the bacteria. The HOSCN defense systems identified in this study may serve as viable targets for novel therapeutics against S. pneumoniae.
JOURNAL OF BACTERIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Fan Yang, Matthew J. Smith, Alexander Griffiths, Alexander Morrell, Sarah J. Chapple, Richard C. M. Siow, Theodora Stewart, Wolfgang Maret, Giovanni E. Mann
Summary: Zinc has various beneficial effects on human coronary artery smooth muscle cells, including antioxidant, anti-inflammatory, and anti-proliferative actions. The supplementation of zinc increases the total intracellular zinc content and enhances the NRF2 signaling pathway, providing protection against oxidative stress. These effects are more pronounced under high oxygen tension compared to normal oxygen conditions.
Correction
Biochemistry & Molecular Biology
Siew Chin Chan, Chih-Wei Tung, Chia-Wei Lin, Yun-Shiuan Tung, Po-Min Wu, Pei-Hsun Cheng, Chuan-Mu Chen, Shang-Hsun Yang
FREE RADICAL BIOLOGY AND MEDICINE
(2024)
Article
Biochemistry & Molecular Biology
Suyuan Liu, Meiling Tan, Jiangxue Cai, Chenxuan Li, Miaoxin Yang, Xiaoxiao Sun, Bin He
Summary: This study reveals that the antibiotic doxycycline effectively inhibits NLRP3 inflammasome activation by targeting mitochondrial translation and mtDNA synthesis, offering potential for the treatment of NLRP3-related diseases.
FREE RADICAL BIOLOGY AND MEDICINE
(2024)
Article
Biochemistry & Molecular Biology
Hao Liu, Nana Li, Ge Kuang, Xia Gong, Ting Wang, Jun Hu, Hui Du, Minxuan Zhong, Jiashi Guo, Yao Xie, Yang Xiang, Shengwang Wu, Yiling Yuan, Xinru Yin, Jingyuan Wan, Ke Li
Summary: Protectin D1 (PTD1) improves hepatic steatosis, inflammation and fibrosis in a NASH mouse model by inhibiting the activation of TLR4 downstream signaling pathway, possibly through upregulation of IRAK-M expression, suggesting a potential new treatment for NASH.
FREE RADICAL BIOLOGY AND MEDICINE
(2024)
