Dph3 Enables Aerobic Diphthamide Biosynthesis by Donating One Iron Atom to Transform a [3Fe–4S] to a [4Fe–4S] Cluster in Dph1–Dph2

Structural Basis of the Substrate Selectivity of Viperin

(2020) Michael K. Fenwick et al.   BIOCHEMISTRY

The asymmetric function of Dph1–Dph2 heterodimer in diphthamide biosynthesis

(2019) Min Dong et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Noncanonical Radical SAM Enzyme Chemistry Learned from Diphthamide Biosynthesis

(2018) Min Dong et al.   BIOCHEMISTRY

Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis

(2018) Min Dong et al.   SCIENCE

A naturally occurring antiviral ribonucleotide encoded by the human genome

(2018) Anthony S. Gizzi et al.   NATURE

Structural studies of viperin, an antiviral radical SAM enzyme

(2017) Michael K. Fenwick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Destruction and reformation of an iron-sulfur cluster during catalysis by lipoyl synthase

(2017) Erin L. McCarthy et al.   SCIENCE

RadicalS-Adenosylmethionine Enzymes in Human Health and Disease

(2016) Bradley J. Landgraf et al.   Annual Review of Biochemistry

Cbr1 is a Dph3 reductase required for the tRNA wobble uridine modification

(2016) Zhewang Lin et al.   Nature Chemical Biology

Elongator, a conserved complex required for wobble uridine modifications in Eukaryotes

(2015) Tony Karlsborn et al.   RNA Biology

Radical S-Adenosylmethionine Enzymes

(2014) Joan B. Broderick et al.   CHEMICAL REVIEWS

Dph3 Is an Electron Donor for Dph1-Dph2 in the First Step of Eukaryotic Diphthamide Biosynthesis

(2014) Min Dong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The diphthamide modification pathway fromSaccharomyces cerevisiae- revisited

(2014) Raffael Schaffrath et al.   MOLECULAR MICROBIOLOGY

Archaeal Elp3 catalyzes tRNA wobble uridine modification at C5 via a radical mechanism

(2014) Kiruthika Selvadurai et al.   Nature Chemical Biology

Identification of a Cyclic Nucleotide as a Cryptic Intermediate in Molybdenum Cofactor Biosynthesis

(2013) Bradley M. Hover et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Electron transfer precedes ATP hydrolysis during nitrogenase catalysis

(2013) S. Duval et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

YBR246W Is Required for the Third Step of Diphthamide Biosynthesis

(2011) Xiaoyang Su et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diphthamide biosynthesis requires an organic radical generated by an iron–sulphur enzyme

(2010) Yang Zhang et al.   NATURE