Design of an Electron-Withdrawing Benzonitrile Ligand for Ni-Catalyzed Cross-Coupling Involving Tertiary Nucleophiles

Regiocontrolled Reductive Vinylation of Aliphatic 1,3-Dienes with Vinyl Triflates by Nickel Catalysis

(2021) Xiaobo Pang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-catalysed anti-Markovnikov hydroarylation of unactivated alkenes with unactivated arenes facilitated by non-covalent interactions

(2020) Noam I. Saper et al.   Nature Chemistry

Nickel-Catalyzed Cross-Electrophile Reductive Couplings of Neopentyl Bromides with Aryl Bromides

(2020) Soumik Biswas et al.   JOURNAL OF ORGANIC CHEMISTRY

Role of Electron-Deficient Olefin Ligands in a Ni-Catalyzed Aziridine Cross-Coupling To Generate Quaternary Carbons

(2020) Jesús G. Estrada et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Evolution of High-Throughput Experimentation in Pharmaceutical Development, and Perspectives on the Future

(2019) Steven M Mennen et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

A one-pot electrophilic cyanation–functionalization strategy for the synthesis of disubstituted malononitriles

(2019) L. Reginald Mills et al.   TETRAHEDRON

Ni-Catalyzed Reductive Cyanation of Aryl Halides and Phenol Derivatives via Transnitrilation

(2019) L. Reginald Mills et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Non-toxic Cyanide Sources and Cyanating Agents

(2018) Alexander Matthias Nauth et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Nickel-Catalyzed 1,2-Diarylation of Simple Alkenyl Amides

(2018) Joseph Derosa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Preparation of Quaternary Centers via Nickel-Catalyzed Suzuki–Miyaura Cross-Coupling of Tertiary Sulfones

(2017) Zachary T. Ariki et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Parameterization of phosphine ligands demonstrates enhancement of nickel catalysis via remote steric effects

(2017) Kevin Wu et al.   Nature Chemistry

Oxidative Addition of Aryl Electrophiles to a Prototypical Nickel(0) Complex: Mechanism and Structure/Reactivity Relationships

(2017) Sonia Bajo et al.   ORGANOMETALLICS

High-Throughput Automation in Chemical Process Development

(2017) Joshua A. Selekman et al.   Annual Review of Chemical and Biomolecular Engineering

Cross-Electrophile Coupling of Vinyl Halides with Alkyl Halides

(2016) Keywan A. Johnson et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-Catalyzed Asymmetric α-Arylation of Alkylnitriles

(2016) Zhiwei Jiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Challenging nickel-catalysed amine arylations enabled by tailored ancillary ligand design

(2016) Christopher M. Lavoie et al.   Nature Communications

New strategies and applications using electrophilic cyanide-transfer reagents under transition metal-free conditions

(2016) Johannes Schörgenhumer et al.   Organic Chemistry Frontiers

Nickel-Catalyzed Amination of Aryl Chlorides with Ammonia or Ammonium Salts

(2015) Rebecca A. Green et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Oxidative Addition of Haloheteroarenes to Palladium(0): Concerted versus SNAr-Type Mechanism

(2015) Bert U. W. Maes et al.   CHEMISTRY-A EUROPEAN JOURNAL

Transnitrilation from Dimethylmalononitrile to Aryl Grignard and Lithium Reagents: A Practical Method for Aryl Nitrile Synthesis

(2015) Jonathan T. Reeves et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Electron-Deficient Olefin Ligands Enable Generation of Quaternary Carbons by Ni-Catalyzed Cross-Coupling

(2015) Chung-Yang (Dennis) Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fundamental Studies and Development of Nickel-Catalyzed Trifluoromethylthiolation of Aryl Chlorides: Active Catalytic Species and Key Roles of Ligand and Traceless MeCN Additive Revealed

(2015) Guoyin Yin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Asymmetric Reductive Cross-Coupling between Heteroaryl Iodides and α-Chloronitriles

(2015) Nathaniel T. Kadunce et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel: The “Spirited Horse” of Transition Metal Catalysis

(2015) Valentine P. Ananikov   ACS Catalysis

Controlling First-Row Catalysts: Amination of Aryl and Heteroaryl Chlorides and Bromides with Primary Aliphatic Amines Catalyzed by a BINAP-Ligated Single-Component Ni(0) Complex

(2014) Shaozhong Ge et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent advances in homogeneous nickel catalysis

(2014) Sarah Z. Tasker et al.   NATURE

1,3-Dicyclohexylimidazol-2-ylidene as a Superior Ligand for the Nickel-Catalyzed Cross-Couplings of Aryl and Benzyl Methyl Ethers with Organoboron Reagents

(2014) Mamoru Tobisu et al.   ORGANIC LETTERS

Nanomole-scale high-throughput chemistry for the synthesis of complex molecules

(2014) A. Buitrago Santanilla et al.   SCIENCE

Metalated nitriles: N- and C-coordination preferences of Li, Mg, and Cu cations

(2013) Matthew Purzycki et al.   CHEMICAL COMMUNICATIONS

Phosphines with Tethered Electron-Withdrawing Olefins as Ligands for Efficient Pd-Catalyzed Aryl-Alkyl Coupling

(2013) Estefanía Gioria et al.   ORGANOMETALLICS

Nickel-Catalyzed Negishi Alkylations of Styrenyl Aziridines

(2012) Chung-Yang (Dennis) Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Synthesis of Secondary Nitriles via Stereoconvergent Negishi Arylations and Alkenylations of Racemic α-Bromonitriles

(2012) Junwon Choi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Growing Impact of Catalysis in the Pharmaceutical Industry

(2011) Carl A. Busacca et al.   ADVANCED SYNTHESIS & CATALYSIS

Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals

(2011) Javier Magano et al.   CHEMICAL REVIEWS

The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

(2011) Stephen D. Roughley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nickel-Catalyzed Asymmetric α-Arylation and Heteroarylation of Ketones with Chloroarenes: Effect of Halide on Selectivity, Oxidation State, and Room-Temperature Reactions

(2011) Shaozhong Ge et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore

(2010) Fraser F. Fleming et al.   JOURNAL OF MEDICINAL CHEMISTRY

Acceleration of Reductive Elimination of [Ar-Pd-C sp 3] by a Phosphine/Electron-Deficient Olefin Ligand: A Kinetic Investigation

(2009) Heng Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-Catalyzed Suzuki−Miyaura Cross-Coupling Reactions Employing Dialkylbiaryl Phosphine Ligands

(2008) Ruben Martin et al.   ACCOUNTS OF CHEMICAL RESEARCH

The Development of Versatile Methods for Palladium-Catalyzed Coupling Reactions of Aryl Electrophiles through the Use of P(t-Bu)3and PCy3as Ligands

(2008) Gregory C. Fu   ACCOUNTS OF CHEMICAL RESEARCH

Well-Defined N-Heterocyclic Carbenes−Palladium(II) Precatalysts for Cross-Coupling Reactions

(2008) Nicolas Marion et al.   ACCOUNTS OF CHEMICAL RESEARCH

More than Bystanders: The Effect of Olefins on Transition-Metal-Catalyzed Cross-Coupling Reactions

(2007) Jeffrey B. Johnson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION